TOP 100 genes for breast_cancer

DRUGSURV is based on 17 clinical breast_cancer expression datasets. Table T1 reports top 100 genes consistently associated with breast_cancer accross available datasets.

Table T1. TOP Genes associated with breast_cancer (the overall number of breast_cancer datasets is 17)

# Gene The Number of
Significant (p-val < 0.01)
datasets
Positive Effect Negative Effect Direct drugs
(aproved)
Direct drugs
(experemental)
Indirect drugs
(aproved)
Indirect drugs
(experemental)
View Gene DRUGSURV Profile
1 MKI67 13 0 13 0 0 82 137 view details
2 CENPA 12 0 12 0 0 32 19 view details
3 UBE2C 12 0 12 0 0 6 4 view details
4 CENPN 11 0 11 0 0 0 0 view details
5 KIF20A 11 0 11 0 0 0 0 view details
6 FOXM1 11 0 11 0 0 1 11 view details
7 ASPM 11 0 11 0 0 2 9 view details
8 NUSAP1 10 0 10 0 0 0 0 view details
9 KPNA2 10 0 10 0 0 17 10 view details
10 HJURP 10 0 10 0 0 0 0 view details
11 PTTG1 10 0 10 0 0 0 4 view details
12 GTSE1 10 0 10 0 0 0 0 view details
13 CENPF 10 0 10 0 0 0 0 view details
14 AURKA 10 0 10 3 18 3 22 view details
15 ALG3 10 0 10 0 0 0 0 view details
16 BIRC5 10 0 10 0 0 3 31 view details
17 CCNB2 9 0 9 0 0 1 145 view details
18 KIF18B 9 0 9 0 0 0 0 view details
19 TPX2 9 0 9 0 0 5 26 view details
20 NCAPG 9 0 9 0 0 0 4 view details
21 MELK 9 0 9 2 7 2 17 view details
22 SPAG5 9 0 9 0 0 0 1 view details
23 CDC20 9 0 9 0 0 4 21 view details
24 CCNE2 9 0 9 0 0 1 141 view details
25 ORC6 9 0 9 0 0 0 1 view details
26 GPSM2 9 0 9 0 0 0 2 view details
27 TTK 9 0 9 3 4 3 4 view details
28 FAM64A 9 0 9 0 0 1 0 view details
29 DLGAP5 9 0 9 0 0 0 0 view details
30 RACGAP1 9 0 9 0 0 2 4 view details
31 KIF2C 9 0 9 0 2 1 1 view details
32 TRIP13 9 0 9 0 0 3 6 view details
33 CCNA2 9 0 9 0 34 1 145 view details
34 NEK2 9 0 9 2 10 10 7 view details
35 BUB1 9 0 9 0 0 2 0 view details
36 PRC1 9 0 9 0 0 0 0 view details
37 ITM2A 9 9 0 0 0 0 0 view details
38 IL6ST 9 9 0 0 0 1 0 view details
39 PTP4A2 8 8 0 0 0 3 15 view details
40 CEP55 8 0 8 0 0 2 0 view details
41 RFC4 8 0 8 0 0 18 31 view details
42 RRM2 8 0 8 2 0 1 0 view details
43 CXCL12 8 8 0 0 1 0 0 view details
44 GAPDH 8 0 8 13 12 107 135 view details
45 TOP2A 8 0 8 23 3 53 80 view details
46 SLC7A5 8 0 8 0 0 0 0 view details
47 LRIG1 8 8 0 0 0 0 0 view details
48 PTGER3 8 8 0 3 0 0 0 view details
49 EBP 8 0 8 6 0 12 12 view details
50 DKC1 8 0 8 0 0 49 84 view details
51 KCMF1 8 0 8 0 0 0 0 view details
52 STMN1 8 0 8 0 0 19 28 view details
53 KIFC1 8 0 8 0 1 0 0 view details
54 THUMPD1 8 8 0 0 0 0 0 view details
55 EXO1 8 0 8 0 0 25 17 view details
56 ESPL1 8 0 8 0 0 0 0 view details
57 PDSS1 8 0 8 0 0 0 0 view details
58 RGS5 8 6 2 0 0 0 0 view details
59 CENPM 8 0 8 0 0 0 0 view details
60 CCNB1 8 0 8 0 0 2 20 view details
61 BCL2 8 8 0 4 0 53 20 view details
62 CREBL2 8 8 0 0 0 0 0 view details
63 IGHA1 8 6 2 0 0 0 0 view details
64 SENP5 7 0 7 0 0 46 59 view details
65 N4BP2L1 7 7 0 0 0 0 0 view details
66 ABAT 7 7 0 6 4 0 0 view details
67 CCNE1 7 0 7 0 0 2 145 view details
68 CENPI 7 0 7 0 0 0 0 view details
69 DONSON 7 0 7 0 0 0 0 view details
70 SMARCA2 7 7 0 0 0 62 61 view details
71 KCTD12 7 7 0 0 0 6 5 view details
72 MCM2 7 0 7 0 0 1 46 view details
73 EIF4E2 7 0 7 0 0 0 0 view details
74 EZH2 7 0 7 2 2 34 23 view details
75 CDKN3 7 0 7 0 0 1 141 view details
76 SRSF5 7 7 0 0 0 104 131 view details
77 ITPR1 7 7 0 0 2 0 0 view details
78 TUBA1C 7 0 7 0 3 6 3 view details
79 SRPK1 7 0 7 1 2 73 81 view details
80 FMO5 7 7 0 0 0 0 0 view details
81 MCM4 7 0 7 0 0 2 1 view details
82 TBC1D9 7 7 0 0 0 0 0 view details
83 EIF4EBP1 7 0 7 0 0 24 16 view details
84 CENPE 7 0 7 0 0 8 4 view details
85 CHEK1 7 0 7 2 39 2 19 view details
86 PPFIA1 7 0 7 0 0 1 2 view details
87 CIAPIN1 7 0 7 0 0 0 0 view details
88 ESR1 7 7 0 46 59 139 221 view details
89 PKMYT1 7 0 7 1 1 8 21 view details
90 ACADSB 7 7 0 2 0 0 0 view details
91 C16ORF61 7 0 7 0 0 0 0 view details
92 BTG2 7 7 0 0 0 0 0 view details
93 RTN1 7 7 0 0 0 0 0 view details
94 GLUL 7 7 0 8 0 25 18 view details
95 FANCI 7 0 7 0 0 5 9 view details
96 HRASLS 7 0 7 0 0 0 0 view details
97 ICA1 7 4 3 0 0 3 17 view details
98 C20ORF24 7 0 7 0 0 2 4 view details
99 CDK1 7 0 7 0 17 44 73 view details
100 HMMR 7 0 7 0 0 0 0 view details


Feel free to use our tools at bioprofiling.de: