Polypharmacology report

Abreviations used here:

  • kA:The number of active compounds known to target the pattern
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the pattern
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )

Individual statistics for (MDM2 and TAAR1) in the assay 686971:

  • kA: 5
  • KA: 7342
  • kB: 5
  • KB: 227332
  • Odds Ratio: 31.0

Table 1. Poly-pharmacological protein patterns (with (MDM2 and TAAR1)) enriched among Active molecules

# Target triplet P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology View
Compounds
details
View Pattern Profile
1 (MDM2 and TAAR1) and TDP1 0.0018 77.5 5 7342 2 227332 Polypharmacology (4) Molecules Target Profile
2 (MDM2 and TAAR1) and TDP1 0.0018 77.5 5 7342 2 227332 Polypharmacology (4) Molecules Target Profile