Polypharmacology report

Abreviations used here:

  • kA:The number of active compounds known to target the pattern
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the pattern
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )

Individual statistics for ABCG2 in the assay 686971:

  • kA: 14
  • KA: 7342
  • kB: 219
  • KB: 227332
  • Odds Ratio: 2.0

Table 1. Poly-pharmacological protein patterns (with ABCG2) enriched among Active molecules

# Target Duplet P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology triplets View
Compounds
details
View Pattern Profile
1 ABCG2 and IDH1 8.71e-12 279.0 9 7342 1 227332 Polypharmacology Molecules Target Profile
2 ABCG2 and NOD1 1.63e-07 185.9 6 7342 1 227332 Polypharmacology Molecules Target Profile
3 ABCG2 and UCHL5 4.12e-06 154.9 5 7342 1 227332 Polypharmacology Molecules Target Profile
4 ABCG2 and NFKB1 1.10e-09 124.0 8 7342 2 227332 Polypharmacology Molecules Target Profile
5 ABCG2 and MITF 1.10e-09 124.0 8 7342 2 227332 Polypharmacology Molecules Target Profile
6 ABCG2 and ADRBK1 0.000101 123.9 4 7342 1 227332 Polypharmacology Molecules Target Profile
7 ABCG2 and JAK2 1.71e-10 93.0 9 7342 3 227332 Polypharmacology Molecules Target Profile
8 ABCG2 and NLRP1 6.17e-07 93.0 6 7342 2 227332 Polypharmacology Molecules Target Profile
9 ABCG2 and NR2F2 6.17e-07 93.0 6 7342 2 227332 Polypharmacology Molecules Target Profile
10 ABCG2 and PKM 1.37e-05 77.5 5 7342 2 227332 Polypharmacology Molecules Target Profile
11 ABCG2 and NOD2 1.37e-05 77.5 5 7342 2 227332 Polypharmacology Molecules Target Profile
12 ABCG2 and NPSR1 1.37e-05 77.5 5 7342 2 227332 Polypharmacology Molecules Target Profile
13 ABCG2 and NR2E3 1.75e-06 62.0 6 7342 3 227332 Polypharmacology Molecules Target Profile
14 ABCG2 and ATXN2 1.75e-06 62.0 6 7342 3 227332 Polypharmacology Molecules Target Profile
15 ABCG2 and RACGAP1 0.006004 46.5 3 7342 2 227332 Polypharmacology Molecules Target Profile
16 ABCG2 and ALPI 0.0022 24.8 4 7342 5 227332 Polypharmacology Molecules Target Profile
17 ABCG2 and STAT3 1.53e-07 23.2 9 7342 12 227332 Polypharmacology Molecules Target Profile
18 ABCG2 and POLB 1.57e-05 19.7 7 7342 11 227332 Polypharmacology Molecules Target Profile
19 ABCG2 and PTGER2 0.00099 17.2 5 7342 9 227332 Polypharmacology Molecules Target Profile
20 ABCG2 and STAT1 6.90e-06 16.5 8 7342 15 227332 Polypharmacology Molecules Target Profile
21 ABCG2 and HTT 3.63e-05 12.4 8 7342 20 227332 Polypharmacology Molecules Target Profile
22 ABCG2 and MAPT 0.00024 11.4 7 7342 19 227332 Polypharmacology Molecules Target Profile
23 ABCG2 and CHRM5 0.00021 9.2 8 7342 27 227332 Polypharmacology Molecules Target Profile
24 ABCG2 and EHMT2 0.00103 8.7 7 7342 25 227332 Polypharmacology Molecules Target Profile
25 ABCG2 and CHRM1 0.00087 7.3 8 7342 34 227332 Polypharmacology Molecules Target Profile