Phenotypic Assay

Table P1. Single Targets Enriched Among Active molecules

  • kA:The number of active compounds known to target the gene
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the gene
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )
# Target (Gene) P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology
report
View
Compounds
details
View Target Profile
1 TNFSF10 6.98e-199 185.2 133 1143 55 77401 Polypharmacology Molecules Target Profile
2 TNFRSF10B 0. 108.3 296 1143 249 77401 Polypharmacology Molecules Target Profile
3 MMP14 9.5e-219 61.3 183 1143 240 77401 Polypharmacology Molecules Target Profile
4 CASP3 3.07e-256 31.9 266 1143 728 77401 Polypharmacology Molecules Target Profile
5 HSP90AA1 7.66e-156 29.2 164 1143 442 77401 Polypharmacology Molecules Target Profile
6 SENP7 2.06e-270 28.7 294 1143 922 77401 Polypharmacology Molecules Target Profile
7 SENP6 1.08e-265 28.4 290 1143 917 77401 Polypharmacology Molecules Target Profile
8 MITF 3.28e-87 26.4 94 1143 262 77401 Polypharmacology Molecules Target Profile
9 EPAS1 1.16e-82 26.4 89 1143 247 77401 Polypharmacology Molecules Target Profile
10 NCOA2 5.40e-29 25.7 31 1143 84 77401 Polypharmacology Molecules Target Profile
11 NPC1 1.36e-299 25.4 347 1143 1308 77401 Polypharmacology Molecules Target Profile
12 SENP8 5.07e-251 24.8 289 1143 1042 77401 Polypharmacology Molecules Target Profile
13 APP 1.84e-175 22.6 206 1143 745 77401 Polypharmacology Molecules Target Profile
14 RAB9A 7.16e-302 22.6 370 1143 1606 77401 Polypharmacology Molecules Target Profile
15 THPO 3.77e-27 20.1 32 1143 111 77401 Polypharmacology Molecules Target Profile
16 SMN2 4.75e-288 19.3 381 1143 1957 77401 Polypharmacology Molecules Target Profile
17 KLF5 3.28e-18 16.7 23 1143 95 77401 Polypharmacology Molecules Target Profile
18 STAT3 5.19e-159 16.5 216 1143 1076 77401 Polypharmacology Molecules Target Profile
19 NR0B1 3.43e-130 16.3 176 1143 853 77401 Polypharmacology Molecules Target Profile
20 PAX8 1.27e-20 14.6 28 1143 133 77401 Polypharmacology Molecules Target Profile
21 NCOA3 2.37e-17 13.8 24 1143 120 77401 Polypharmacology Molecules Target Profile
22 STAT1 2.52e-156 13.1 242 1143 1558 77401 Polypharmacology Molecules Target Profile
23 RORA 6.77e-91 10.6 155 1143 1130 77401 Polypharmacology Molecules Target Profile
24 NR5A1 4.44e-112 10.5 195 1143 1492 77401 Polypharmacology Molecules Target Profile
25 XBP1 1.57e-06 10.3 10 1143 66 77401 Polypharmacology Molecules Target Profile
26 BLM 1.30e-18 10.0 31 1143 215 77401 Polypharmacology Molecules Target Profile
27 NOD2 3.05e-19 9.6 33 1143 239 77401 Polypharmacology Molecules Target Profile
28 MTOR 4.80e-38 9.6 67 1143 500 77401 Polypharmacology Molecules Target Profile
29 NLRP3 3.99e-18 9.6 31 1143 225 77401 Polypharmacology Molecules Target Profile
30 NFKB1 4.66e-19 9.4 33 1143 243 77401 Polypharmacology Molecules Target Profile
31 CDC25B 1.08e-06 9.3 11 1143 81 77401 Polypharmacology Molecules Target Profile
32 NOD1 1.05e-27 8.8 51 1143 409 77401 Polypharmacology Molecules Target Profile
33 STK33 3.58e-12 8.0 23 1143 197 77401 Polypharmacology Molecules Target Profile
34 MAPK1 1.22e-37 7.7 77 1143 718 77401 Polypharmacology Molecules Target Profile
35 NR2F2 8.68e-17 7.4 34 1143 318 77401 Polypharmacology Molecules Target Profile
36 CFTR 1.14e-20 7.3 43 1143 412 77401 Polypharmacology Molecules Target Profile
37 ATXN2 2.04e-30 6.9 67 1143 690 77401 Polypharmacology Molecules Target Profile
38 CASP1 1.56e-05 6.8 11 1143 110 77401 Polypharmacology Molecules Target Profile
39 PKM 2.74e-14 6.5 32 1143 342 77401 Polypharmacology Molecules Target Profile
40 HNF4A 1.09e-08 6.4 19 1143 204 77401 Polypharmacology Molecules Target Profile
41 ALOX15B 4.60e-09 6.4 20 1143 216 77401 Polypharmacology Molecules Target Profile
42 USP1 4.37e-16 6.3 37 1143 409 77401 Polypharmacology Molecules Target Profile
43 IDH1 8.07e-35 6.3 84 1143 970 77401 Polypharmacology Molecules Target Profile
44 ATAD5 1.58e-89 6.2 232 1143 3050 77401 Polypharmacology Molecules Target Profile
45 CXCR6 3.57e-05 6.2 11 1143 121 77401 Polypharmacology Molecules Target Profile
46 TNF 2.99e-08 6.0 19 1143 218 77401 Polypharmacology Molecules Target Profile
47 PAFAH1B3 0.00011 6.0 10 1143 114 77401 Polypharmacology Molecules Target Profile
48 HIF1A 1.62e-19 5.9 48 1143 569 77401 Polypharmacology Molecules Target Profile
49 VDR 9.06e-31 5.9 78 1143 954 77401 Polypharmacology Molecules Target Profile
50 PADI4 1.13e-06 4.9 18 1143 251 77401 Polypharmacology Molecules Target Profile
51 S1PR1 6.79e-09 4.9 25 1143 355 77401 Polypharmacology Molecules Target Profile
52 CYP19A1 5.41e-06 4.6 17 1143 252 77401 Polypharmacology Molecules Target Profile
53 S1PR4 4.31e-06 4.5 18 1143 277 77401 Polypharmacology Molecules Target Profile
54 GAPDH 5.01e-12 4.4 38 1143 594 77401 Polypharmacology Molecules Target Profile
55 CCR6 0.00062 4.3 11 1143 174 77401 Polypharmacology Molecules Target Profile
56 GALR2 1.96e-07 4.2 24 1143 394 77401 Polypharmacology Molecules Target Profile
57 JAK2 2.36e-09 4.2 31 1143 513 77401 Polypharmacology Molecules Target Profile
58 SMARCA2 1.20e-10 4.1 36 1143 603 77401 Polypharmacology Molecules Target Profile
59 NR5A2 7.38e-05 4.1 15 1143 248 77401 Polypharmacology Molecules Target Profile
60 TLR3 0.00026 4.1 13 1143 216 77401 Polypharmacology Molecules Target Profile
61 MAPT 2.81e-37 4.0 146 1143 2763 77401 Polypharmacology Molecules Target Profile
62 SMAD3 1.06e-18 3.8 72 1143 1334 77401 Polypharmacology Molecules Target Profile
63 APLNR 0.002002 3.7 11 1143 203 77401 Polypharmacology Molecules Target Profile
64 ADRB2 0.00039 3.7 14 1143 259 77401 Polypharmacology Molecules Target Profile
65 PAFAH2 0.0001003 3.5 18 1143 357 77401 Polypharmacology Molecules Target Profile
66 NR2E3 0.00021 3.4 17 1143 345 77401 Polypharmacology Molecules Target Profile
67 S1PR3 0.0018 3.3 13 1143 269 77401 Polypharmacology Molecules Target Profile
68 HCRTR1 3.32e-11 3.2 54 1143 1193 77401 Polypharmacology Molecules Target Profile
69 ALOX15 3.13e-09 3.1 45 1143 1009 77401 Polypharmacology Molecules Target Profile
70 CTSL1 0.0012 3.0 16 1143 367 77401 Polypharmacology Molecules Target Profile
71 NPSR1 3.91e-05 3.0 25 1143 582 77401 Polypharmacology Molecules Target Profile
72 AURKC 0.0065 67.8 2 1143 2 77401 Polypharmacology Molecules Target Profile
73 CDC25A 0.0065 67.8 2 1143 2 77401 Polypharmacology Molecules Target Profile
74 LHCGR 0.0103 45.2 2 1143 3 77401 Polypharmacology Molecules Target Profile
75 MAP2K1 0.0103 45.2 2 1143 3 77401 Polypharmacology Molecules Target Profile
76 YES1 0.00014 34.0 4 1143 8 77401 Polypharmacology Molecules Target Profile
77 DRD5P1 0.014 33.9 2 1143 4 77401 Polypharmacology Molecules Target Profile
78 NQO2 0.014 33.9 2 1143 4 77401 Polypharmacology Molecules Target Profile
79 CDK5 0.014 33.9 2 1143 4 77401 Polypharmacology Molecules Target Profile
80 EIF2AK2 0.014 33.9 2 1143 4 77401 Polypharmacology Molecules Target Profile
81 AURKA 0.014 33.9 2 1143 4 77401 Polypharmacology Molecules Target Profile
82 AURKB 0.018 27.1 2 1143 5 77401 Polypharmacology Molecules Target Profile
83 GALK1 9.56e-07 23.8 7 1143 20 77401 Polypharmacology Molecules Target Profile
84 PARK2 0.0034 22.6 3 1143 9 77401 Polypharmacology Molecules Target Profile
85 SMN1 0.023 22.6 2 1143 6 77401 Polypharmacology Molecules Target Profile
86 ODC1 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
87 BRAF 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
88 UGT1A4 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
89 ESRRA 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
90 MC3R 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
91 CES2 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
92 KIF11 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
93 NQO1 0.15 22.6 1 1143 3 77401 Polypharmacology Molecules Target Profile
94 GRM5 0.028 19.4 2 1143 7 77401 Polypharmacology Molecules Target Profile
95 SLK 0.034 17.0 2 1143 8 77401 Polypharmacology Molecules Target Profile
96 FMO3 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
97 RIPK2 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
98 MTHFR 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
99 MTNR1B 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
100 MTNR1A 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
101 CDK1 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
102 TACR1 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
103 CSNK1G1 0.18 16.9 1 1143 4 77401 Polypharmacology Molecules Target Profile
104 STAT6 5.04e-05 15.7 6 1143 26 77401 Polypharmacology Molecules Target Profile
105 HSPA1A 0.0074 15.7 3 1143 13 77401 Polypharmacology Molecules Target Profile
106 MAP3K5 0.0403 15.1 2 1143 9 77401 Polypharmacology Molecules Target Profile
107 HCRTR2 0.0088 14.5 3 1143 14 77401 Polypharmacology Molecules Target Profile
108 AGTR1 0.00039 14.2 5 1143 24 77401 Polypharmacology Molecules Target Profile
109 PIN1 0.044 13.6 2 1143 10 77401 Polypharmacology Molecules Target Profile
110 CDK2 0.21 13.6 1 1143 5 77401 Polypharmacology Molecules Target Profile
111 KEAP1 0.21 13.6 1 1143 5 77401 Polypharmacology Molecules Target Profile
112 GSR 0.21 13.6 1 1143 5 77401 Polypharmacology Molecules Target Profile
113 KDM4A 0.0508 12.3 2 1143 11 77401 Polypharmacology Molecules Target Profile
114 ARSA 0.014 12.0 3 1143 17 77401 Polypharmacology Molecules Target Profile
115 MAOB 0.015 11.3 3 1143 18 77401 Polypharmacology Molecules Target Profile
116 CES1 0.23 11.3 1 1143 6 77401 Polypharmacology Molecules Target Profile
117 CSNK2A1 0.23 11.3 1 1143 6 77401 Polypharmacology Molecules Target Profile
118 MC5R 0.23 11.3 1 1143 6 77401 Polypharmacology Molecules Target Profile
119 IDO1 0.23 11.3 1 1143 6 77401 Polypharmacology Molecules Target Profile
120 NTSR1 5.95e-06 10.4 9 1143 59 77401 Polypharmacology Molecules Target Profile
121 MLL 0.026 8.9 3 1143 23 77401 Polypharmacology Molecules Target Profile
122 NCOA1 2.29e-05 8.6 9 1143 71 77401 Polypharmacology Molecules Target Profile
123 PTPN22 0.0028 8.5 5 1143 40 77401 Polypharmacology Molecules Target Profile
124 S100A4 0.087 8.5 2 1143 16 77401 Polypharmacology Molecules Target Profile
125 RGS12 0.087 8.5 2 1143 16 77401 Polypharmacology Molecules Target Profile
126 EBP 0.28 8.5 1 1143 8 77401 Polypharmacology Molecules Target Profile
127 GRM1 0.28 8.5 1 1143 8 77401 Polypharmacology Molecules Target Profile
128 STK16 0.28 8.5 1 1143 8 77401 Polypharmacology Molecules Target Profile
129 HBB 0.00028 8.4 7 1143 57 77401 Polypharmacology Molecules Target Profile
130 MAOA 0.0109 8.0 4 1143 34 77401 Polypharmacology Molecules Target Profile
131 NFKBIA 0.012 7.5 4 1143 36 77401 Polypharmacology Molecules Target Profile
132 ERG 0.104 7.5 2 1143 18 77401 Polypharmacology Molecules Target Profile
133 CLK3 0.302 7.5 1 1143 9 77401 Polypharmacology Molecules Target Profile
134 P4HB 0.039 7.3 3 1143 28 77401 Polypharmacology Molecules Target Profile
135 HKDC1 7.89e-05 7.2 9 1143 85 77401 Polypharmacology Molecules Target Profile
136 TLR9 9.21e-05 7.1 9 1143 87 77401 Polypharmacology Molecules Target Profile
137 CALM1 0.31 6.8 1 1143 10 77401 Polypharmacology Molecules Target Profile
138 CALM2 0.31 6.8 1 1143 10 77401 Polypharmacology Molecules Target Profile
139 MBNL1 0.0069 6.7 5 1143 51 77401 Polypharmacology Molecules Target Profile
140 RXRA 0.018 6.6 4 1143 41 77401 Polypharmacology Molecules Target Profile
141 HTR1B 0.047 6.6 3 1143 31 77401 Polypharmacology Molecules Target Profile
142 GLA 0.13 6.5 2 1143 21 77401 Polypharmacology Molecules Target Profile
143 LYPLA1 0.00051 6.3 8 1143 87 77401 Polypharmacology Molecules Target Profile
144 DRD4 0.053 6.2 3 1143 33 77401 Polypharmacology Molecules Target Profile
145 XDH 0.35 6.2 1 1143 11 77401 Polypharmacology Molecules Target Profile
146 NOX1 0.35 6.2 1 1143 11 77401 Polypharmacology Molecules Target Profile
147 LCK 0.35 6.2 1 1143 11 77401 Polypharmacology Molecules Target Profile
148 TLR4 0.0015 6.1 7 1143 78 77401 Polypharmacology Molecules Target Profile
149 HTR1D 0.056 6.0 3 1143 34 77401 Polypharmacology Molecules Target Profile
150 PPARD 0.00071 5.9 8 1143 92 77401 Polypharmacology Molecules Target Profile
151 CTSS 0.058 5.8 3 1143 35 77401 Polypharmacology Molecules Target Profile
152 EYA2 0.028 5.7 4 1143 48 77401 Polypharmacology Molecules Target Profile
153 TBXAS1 0.36 5.6 1 1143 12 77401 Polypharmacology Molecules Target Profile
154 XIAP 0.36 5.6 1 1143 12 77401 Polypharmacology Molecules Target Profile
155 CA3 0.068 5.5 3 1143 37 77401 Polypharmacology Molecules Target Profile
156 OPRD1 0.16 5.4 2 1143 25 77401 Polypharmacology Molecules Target Profile
157 MPHOSPH8 0.00303 5.4 7 1143 89 77401 Polypharmacology Molecules Target Profile
158 MAPK14 0.38 5.2 1 1143 13 77401 Polypharmacology Molecules Target Profile
159 AVPR1A 0.0038 5.1 7 1143 93 77401 Polypharmacology Molecules Target Profile
160 SNCA 0.0018 5.1 8 1143 107 77401 Polypharmacology Molecules Target Profile
161 CYP1B1 0.18 5.0 2 1143 27 77401 Polypharmacology Molecules Target Profile
162 OPRM1 0.087 4.8 3 1143 42 77401 Polypharmacology Molecules Target Profile
163 BCL2L2 0.39 4.8 1 1143 14 77401 Polypharmacology Molecules Target Profile
164 ERBB2 0.39 4.8 1 1143 14 77401 Polypharmacology Molecules Target Profile
165 ADRB3 0.39 4.8 1 1143 14 77401 Polypharmacology Molecules Target Profile
166 CALM3 0.39 4.8 1 1143 14 77401 Polypharmacology Molecules Target Profile
167 DUSP1 0.0055 4.8 7 1143 100 77401 Polypharmacology Molecules Target Profile
168 CASP7 0.022 4.7 5 1143 72 77401 Polypharmacology Molecules Target Profile
169 ALOX12 0.013 4.6 6 1143 89 77401 Polypharmacology Molecules Target Profile
170 CA5B 0.101 4.5 3 1143 45 77401 Polypharmacology Molecules Target Profile
171 CA6 0.101 4.5 3 1143 45 77401 Polypharmacology Molecules Target Profile
172 GPR35 0.203 4.5 2 1143 30 77401 Polypharmacology Molecules Target Profile
173 SLC22A2 0.42 4.5 1 1143 15 77401 Polypharmacology Molecules Target Profile
174 PLIN1 0.42 4.5 1 1143 15 77401 Polypharmacology Molecules Target Profile
175 AOX1 0.42 4.5 1 1143 15 77401 Polypharmacology Molecules Target Profile
176 DCLRE1C 0.014 4.4 6 1143 92 77401 Polypharmacology Molecules Target Profile
177 ATM 0.028 4.4 5 1143 77 77401 Polypharmacology Molecules Target Profile
178 KDM4C 0.21 4.4 2 1143 31 77401 Polypharmacology Molecules Target Profile
179 ADORA3 0.056 4.3 4 1143 63 77401 Polypharmacology Molecules Target Profile
180 RAPGEF3 0.058 4.2 4 1143 64 77401 Polypharmacology Molecules Target Profile
181 CA5A 0.11 4.2 3 1143 48 77401 Polypharmacology Molecules Target Profile
182 CA13 0.44 4.2 1 1143 16 77401 Polypharmacology Molecules Target Profile
183 CA7 0.12 4.2 3 1143 49 77401 Polypharmacology Molecules Target Profile
184 NR1H4 0.0031 4.1 9 1143 149 77401 Polypharmacology Molecules Target Profile
185 CA4 0.12 4.1 3 1143 50 77401 Polypharmacology Molecules Target Profile
186 CYP1A1 0.13 4.0 3 1143 51 77401 Polypharmacology Molecules Target Profile
187 DAGLB 0.45 4.0 1 1143 17 77401 Polypharmacology Molecules Target Profile
188 PTPN5 0.0405 3.9 5 1143 86 77401 Polypharmacology Molecules Target Profile
189 CA14 0.14 3.8 3 1143 53 77401 Polypharmacology Molecules Target Profile
190 CYP2E1 0.14 3.8 3 1143 53 77401 Polypharmacology Molecules Target Profile
191 ACP1 0.044 3.8 5 1143 89 77401 Polypharmacology Molecules Target Profile
192 CTSB 0.082 3.8 4 1143 72 77401 Polypharmacology Molecules Target Profile
193 USP2 0.028 3.7 6 1143 109 77401 Polypharmacology Molecules Target Profile
194 TDP2 0.0109 3.7 8 1143 149 77401 Polypharmacology Molecules Target Profile
195 SLC6A2 0.093 3.6 4 1143 76 77401 Polypharmacology Molecules Target Profile
196 ADORA2B 0.49 3.6 1 1143 19 77401 Polypharmacology Molecules Target Profile
197 SLC22A1 0.49 3.6 1 1143 19 77401 Polypharmacology Molecules Target Profile
198 CYP3A7 0.28 3.4 2 1143 40 77401 Polypharmacology Molecules Target Profile
199 FKBP1A 0.506 3.4 1 1143 20 77401 Polypharmacology Molecules Target Profile
200 FYN 0.506 3.4 1 1143 20 77401 Polypharmacology Molecules Target Profile
201 UCHL5 0.015 3.4 8 1143 161 77401 Polypharmacology Molecules Target Profile
202 HTR2A 0.068 3.3 5 1143 102 77401 Polypharmacology Molecules Target Profile
203 PPP5C 0.047 3.2 6 1143 126 77401 Polypharmacology Molecules Target Profile
204 TACR2 0.51 3.2 1 1143 21 77401 Polypharmacology Molecules Target Profile
205 HSPB1 0.0308 3.2 7 1143 148 77401 Polypharmacology Molecules Target Profile
206 GLS 0.014 3.2 9 1143 193 77401 Polypharmacology Molecules Target Profile
207 PTPN7 0.13 3.1 4 1143 88 77401 Polypharmacology Molecules Target Profile
208 CA12 0.205 3.1 3 1143 66 77401 Polypharmacology Molecules Target Profile
209 CA9 0.21 3.0 3 1143 67 77401 Polypharmacology Molecules Target Profile
210 CYP2A6 0.31 3.0 2 1143 45 77401 Polypharmacology Molecules Target Profile
211 OXTR 0.028 3.0 8 1143 181 77401 Polypharmacology Molecules Target Profile
212 HTR2C 0.15 3.0 4 1143 92 77401 Polypharmacology Molecules Target Profile
213 CA1 0.21 2.9 3 1143 69 77401 Polypharmacology Molecules Target Profile
214 MDM2 0.33 2.9 2 1143 46 77401 Polypharmacology Molecules Target Profile
215 GSTO1 4.20e-05 2.9 25 1143 585 77401 Polypharmacology Molecules Target Profile
216 WEE1 0.00013 2.9 22 1143 514 77401 Polypharmacology Molecules Target Profile
217 GLP1R 2.24e-10 2.9 56 1143 1338 77401 Polypharmacology Molecules Target Profile
218 KAT2A 0.0103 2.9 11 1143 256 77401 Polypharmacology Molecules Target Profile
219 AHR 8.25e-14 2.9 77 1143 1865 77401 Polypharmacology Molecules Target Profile
220 VCP 0.0508 2.8 7 1143 167 77401 Polypharmacology Molecules Target Profile
221 IL1B 4.25e-13 2.8 76 1143 1889 77401 Polypharmacology Molecules Target Profile
222 NR1I2 0.00014 2.8 23 1143 556 77401 Polypharmacology Molecules Target Profile
223 ADRB1 0.58 2.8 1 1143 24 77401 Polypharmacology Molecules Target Profile
224 ADRA1B 0.58 2.8 1 1143 24 77401 Polypharmacology Molecules Target Profile
225 LYPLA2 0.038 2.8 8 1143 194 77401 Polypharmacology Molecules Target Profile
226 IDE 0.028 2.8 9 1143 221 77401 Polypharmacology Molecules Target Profile
227 WRN 0.019 2.8 10 1143 246 77401 Polypharmacology Molecules Target Profile
228 FEN1 0.019 2.8 10 1143 246 77401 Polypharmacology Molecules Target Profile
229 HTR2B 0.18 2.7 4 1143 100 77401 Polypharmacology Molecules Target Profile
230 MLLT3 0.18 2.7 4 1143 100 77401 Polypharmacology Molecules Target Profile
231 OPRK1 0.25 2.7 3 1143 75 77401 Polypharmacology Molecules Target Profile
232 GPR183 0.00303 2.7 16 1143 404 77401 Polypharmacology Molecules Target Profile
233 MAPK10 0.0088 2.7 13 1143 329 77401 Polypharmacology Molecules Target Profile
234 ASAP1 0.26 2.7 3 1143 76 77401 Polypharmacology Molecules Target Profile
235 GMNN 1.64e-11 2.7 74 1143 1959 77401 Polypharmacology Molecules Target Profile
236 CYP3A5 0.38 2.7 2 1143 51 77401 Polypharmacology Molecules Target Profile
237 PPME1 0.019 2.6 11 1143 287 77401 Polypharmacology Molecules Target Profile
238 CA2 0.26 2.6 3 1143 78 77401 Polypharmacology Molecules Target Profile
239 PTGS1 0.38 2.6 2 1143 52 77401 Polypharmacology Molecules Target Profile
240 ADRA1D 0.38 2.6 2 1143 52 77401 Polypharmacology Molecules Target Profile
241 BCL2 0.59 2.6 1 1143 26 77401 Polypharmacology Molecules Target Profile
242 HTR1A 7.67e-05 2.6 29 1143 771 77401 Polypharmacology Molecules Target Profile
243 RAD54L 0.19 2.6 4 1143 105 77401 Polypharmacology Molecules Target Profile
244 RBBP8 0.053 2.6 8 1143 211 77401 Polypharmacology Molecules Target Profile
245 CBX1 0.0065 2.6 15 1143 399 77401 Polypharmacology Molecules Target Profile
246 ATG4B 0.033 2.5 10 1143 271 77401 Polypharmacology Molecules Target Profile
247 PPARG 0.044 2.5 9 1143 244 77401 Polypharmacology Molecules Target Profile
248 BRCA1 4.67e-05 2.4 34 1143 958 77401 Polypharmacology Molecules Target Profile
249 APAF1 0.0019 2.4 21 1143 590 77401 Polypharmacology Molecules Target Profile
250 S1PR2 0.0302 2.4 11 1143 308 77401 Polypharmacology Molecules Target Profile
251 ABCB1 0.101 2.4 7 1143 199 77401 Polypharmacology Molecules Target Profile
252 MMP13 0.42 2.4 2 1143 57 77401 Polypharmacology Molecules Target Profile
253 NFE2L2 3.50e-11 2.4 90 1143 2691 77401 Polypharmacology Molecules Target Profile
254 POLK 0.0044 2.4 19 1143 548 77401 Polypharmacology Molecules Target Profile
255 MC4R 0.002002 2.4 22 1143 637 77401 Polypharmacology Molecules Target Profile
256 AR 0.0103 2.4 16 1143 462 77401 Polypharmacology Molecules Target Profile
257 CLK1 0.42 2.3 2 1143 58 77401 Polypharmacology Molecules Target Profile
258 BCHE 0.64 2.3 1 1143 29 77401 Polypharmacology Molecules Target Profile
259 PRNP 0.082 2.3 8 1143 233 77401 Polypharmacology Molecules Target Profile
260 TRPV1 0.31 2.3 3 1143 88 77401 Polypharmacology Molecules Target Profile
261 BCL2A1 0.44 2.3 2 1143 59 77401 Polypharmacology Molecules Target Profile
262 ADRA2B 0.44 2.3 2 1143 59 77401 Polypharmacology Molecules Target Profile
263 GNAS 0.202 2.3 5 1143 150 77401 Polypharmacology Molecules Target Profile
264 APOBEC3F 0.058 2.3 10 1143 302 77401 Polypharmacology Molecules Target Profile
265 GSK3B 0.26 2.2 4 1143 125 77401 Polypharmacology Molecules Target Profile
266 SIX1 0.11 2.2 8 1143 252 77401 Polypharmacology Molecules Target Profile
267 TRA@ 0.28 2.1 4 1143 128 77401 Polypharmacology Molecules Target Profile
268 APOBEC3G 0.024 2.1 16 1143 518 77401 Polypharmacology Molecules Target Profile
269 L3MBTL1 0.082 2.1 10 1143 323 77401 Polypharmacology Molecules Target Profile
270 RAD52 0.506 2.1 2 1143 66 77401 Polypharmacology Molecules Target Profile
271 RXFP2 0.706 2.1 1 1143 33 77401 Polypharmacology Molecules Target Profile
272 DLD 0.093 2.0 10 1143 332 77401 Polypharmacology Molecules Target Profile
273 HTR1E 0.0029 2.0 29 1143 977 77401 Polypharmacology Molecules Target Profile
274 RACGAP1 0.18 2.0 7 1143 236 77401 Polypharmacology Molecules Target Profile
275 WHSC1 0.19 2.0 7 1143 242 77401 Polypharmacology Molecules Target Profile
276 SLC6A4 0.51 2.0 2 1143 69 77401 Polypharmacology Molecules Target Profile
277 HTT 0.00047 2.0 43 1143 1518 77401 Polypharmacology Molecules Target Profile
278 HRH2 0.73 1.9 1 1143 35 77401 Polypharmacology Molecules Target Profile
279 SIGMAR1 0.73 1.9 1 1143 35 77401 Polypharmacology Molecules Target Profile
280 RGS4 0.019 1.9 21 1143 742 77401 Polypharmacology Molecules Target Profile
281 HPGD 1.08e-06 1.9 83 1143 3015 77401 Polypharmacology Molecules Target Profile
282 THRB 0.053 1.9 15 1143 533 77401 Polypharmacology Molecules Target Profile
283 DRD5 0.42 1.9 3 1143 107 77401 Polypharmacology Molecules Target Profile
284 FASN 0.302 1.9 5 1143 179 77401 Polypharmacology Molecules Target Profile
285 TARDBP 0.00015 1.9 55 1143 2023 77401 Polypharmacology Molecules Target Profile
286 AVPR1B 0.73 1.9 1 1143 36 77401 Polypharmacology Molecules Target Profile
287 UBE2N 0.31 1.9 5 1143 183 77401 Polypharmacology Molecules Target Profile
288 CTNNB1 0.31 1.8 5 1143 185 77401 Polypharmacology Molecules Target Profile
289 CYP2B7P1 0.74 1.8 1 1143 37 77401 Polypharmacology Molecules Target Profile
290 COPS5 0.31 1.8 5 1143 187 77401 Polypharmacology Molecules Target Profile
291 ADRA2A 0.58 1.8 2 1143 75 77401 Polypharmacology Molecules Target Profile
292 CASP6 0.45 1.8 3 1143 113 77401 Polypharmacology Molecules Target Profile
293 PRMT1 0.028 1.8 23 1143 874 77401 Polypharmacology Molecules Target Profile
294 EGFR 0.75 1.8 1 1143 38 77401 Polypharmacology Molecules Target Profile
295 HTR5A 0.15 1.8 11 1143 421 77401 Polypharmacology Molecules Target Profile
296 CYP3A4 6.47e-06 1.8 93 1143 3678 77401 Polypharmacology Molecules Target Profile
297 TAAR1 0.019 1.8 28 1143 1088 77401 Polypharmacology Molecules Target Profile
298 GPR55 0.59 1.7 2 1143 78 77401 Polypharmacology Molecules Target Profile
299 PTK2B 0.77 1.7 1 1143 39 77401 Polypharmacology Molecules Target Profile
300 ROCK2 0.36 1.7 5 1143 197 77401 Polypharmacology Molecules Target Profile
301 KCNQ1 0.0709 1.7 19 1143 758 77401 Polypharmacology Molecules Target Profile
302 CHRM4 0.065 1.7 20 1143 801 77401 Polypharmacology Molecules Target Profile
303 DUSP3 0.33 1.7 6 1143 240 77401 Polypharmacology Molecules Target Profile
304 ADORA1 0.78 1.7 1 1143 40 77401 Polypharmacology Molecules Target Profile
305 CYP2B6 0.78 1.7 1 1143 40 77401 Polypharmacology Molecules Target Profile
306 NLRP1 0.23 1.7 9 1143 362 77401 Polypharmacology Molecules Target Profile
307 MCOLN1 0.51 1.7 3 1143 121 77401 Polypharmacology Molecules Target Profile
308 GNA15 0.24 1.7 9 1143 365 77401 Polypharmacology Molecules Target Profile
309 POLH 0.058 1.7 22 1143 897 77401 Polypharmacology Molecules Target Profile
310 PTK2 0.21 1.7 10 1143 407 77401 Polypharmacology Molecules Target Profile
311 EPHX2 0.44 1.7 4 1143 164 77401 Polypharmacology Molecules Target Profile
312 PDE4B 0.78 1.7 1 1143 41 77401 Polypharmacology Molecules Target Profile
313 MBD2 0.47 1.6 4 1143 168 77401 Polypharmacology Molecules Target Profile
314 ABCB6 0.42 1.6 5 1143 212 77401 Polypharmacology Molecules Target Profile
315 MRGPRX1 0.031 1.6 34 1143 1460 77401 Polypharmacology Molecules Target Profile
316 EIF2AK3 0.65 1.6 2 1143 85 77401 Polypharmacology Molecules Target Profile
317 KLK7 0.13 1.6 18 1143 778 77401 Polypharmacology Molecules Target Profile
318 PTGS2 0.809 1.6 1 1143 43 77401 Polypharmacology Molecules Target Profile
319 GFER 0.0069 1.6 56 1143 2460 77401 Polypharmacology Molecules Target Profile
320 CYP1A2 0.000507 1.6 92 1143 4105 77401 Polypharmacology Molecules Target Profile
321 PREPL 0.25 1.6 11 1143 479 77401 Polypharmacology Molecules Target Profile
322 ESR2 0.13 1.6 19 1143 832 77401 Polypharmacology Molecules Target Profile
323 ACHE 0.82 1.5 1 1143 44 77401 Polypharmacology Molecules Target Profile
324 TDP1 2.47e-11 1.5 459 1143 23500 77401 Polypharmacology Molecules Target Profile
325 MCOLN3 0.58 1.5 3 1143 133 77401 Polypharmacology Molecules Target Profile
326 DNMT1 0.28 1.5 11 1143 492 77401 Polypharmacology Molecules Target Profile
327 POLI 0.15 1.5 20 1143 900 77401 Polypharmacology Molecules Target Profile
328 ADRA1A 0.83 1.5 1 1143 45 77401 Polypharmacology Molecules Target Profile
329 PPP1CA 0.31 1.5 10 1143 452 77401 Polypharmacology Molecules Target Profile
330 CTSG 0.706 1.5 2 1143 91 77401 Polypharmacology Molecules Target Profile
331 LARGE 0.62 1.5 3 1143 139 77401 Polypharmacology Molecules Target Profile
332 PHOSPHO1 0.17 1.5 22 1143 1031 77401 Polypharmacology Molecules Target Profile
333 F2 0.58 1.4 4 1143 192 77401 Polypharmacology Molecules Target Profile
334 CLK4 0.44 1.4 8 1143 387 77401 Polypharmacology Molecules Target Profile
335 TUBB 0.39 1.4 10 1143 488 77401 Polypharmacology Molecules Target Profile
336 PTGER2 0.21 1.4 23 1143 1129 77401 Polypharmacology Molecules Target Profile
337 INS 0.28 1.4 17 1143 835 77401 Polypharmacology Molecules Target Profile
338 C1S 0.74 1.4 2 1143 98 77401 Polypharmacology Molecules Target Profile
339 RELA 0.85 1.4 1 1143 49 77401 Polypharmacology Molecules Target Profile
340 AKT1 0.35 1.4 14 1143 702 77401 Polypharmacology Molecules Target Profile
341 CHRM2 0.86 1.4 1 1143 50 77401 Polypharmacology Molecules Target Profile
342 TRHR 0.33 1.4 15 1143 754 77401 Polypharmacology Molecules Target Profile
343 CHRM5 0.42 1.3 12 1143 611 77401 Polypharmacology Molecules Target Profile
344 ADORA2A 0.88 1.3 1 1143 51 77401 Polypharmacology Molecules Target Profile
345 ADRA2C 0.89 1.3 1 1143 52 77401 Polypharmacology Molecules Target Profile
346 SELE 0.58 1.3 7 1143 368 77401 Polypharmacology Molecules Target Profile
347 PAFAH1B2 0.47 1.3 11 1143 579 77401 Polypharmacology Molecules Target Profile
348 ADAM10 0.62 1.3 6 1143 321 77401 Polypharmacology Molecules Target Profile
349 DRD3 0.18 1.3 50 1143 2715 77401 Polypharmacology Molecules Target Profile
350 PLK1 0.22 1.3 42 1143 2279 77401 Polypharmacology Molecules Target Profile
351 RBBP9 0.809 1.3 2 1143 108 77401 Polypharmacology Molecules Target Profile
352 ADAM17 0.61 1.2 7 1143 382 77401 Polypharmacology Molecules Target Profile
353 ALPI 0.75 1.2 3 1143 164 77401 Polypharmacology Molecules Target Profile
354 CHRM3 0.92 1.2 1 1143 55 77401 Polypharmacology Molecules Target Profile
355 EHMT2 0.077 1.2 130 1143 7395 77401 Polypharmacology Molecules Target Profile
356 NR3C1 0.706 1.2 5 1143 279 77401 Polypharmacology Molecules Target Profile
357 ESR1 0.31 1.2 40 1143 2263 77401 Polypharmacology Molecules Target Profile
358 KCNJ1 0.59 1.2 11 1143 628 77401 Polypharmacology Molecules Target Profile
359 RAPGEF4 0.85 1.2 2 1143 115 77401 Polypharmacology Molecules Target Profile
360 BCL2L1 0.64 1.2 10 1143 580 77401 Polypharmacology Molecules Target Profile
361 SLC5A7 0.51 1.2 20 1143 1162 77401 Polypharmacology Molecules Target Profile
362 POLB 0.51 1.2 22 1143 1289 77401 Polypharmacology Molecules Target Profile
363 MCL1 0.506 1.2 27 1143 1594 77401 Polypharmacology Molecules Target Profile
364 YWHAG 0.94 1.1 1 1143 59 77401 Polypharmacology Molecules Target Profile
365 CHRM1 0.62 1.1 16 1143 955 77401 Polypharmacology Molecules Target Profile
366 DRD1 0.36 1.1 74 1143 4478 77401 Polypharmacology Molecules Target Profile
367 ITGA4 0.77 1.1 6 1143 361 77401 Polypharmacology Molecules Target Profile
368 MAP1LC3A 0.74 1.1 9 1143 549 77401 Polypharmacology Molecules Target Profile
369 PIP4K2A 0.75 1.1 8 1143 488 77401 Polypharmacology Molecules Target Profile
370 HRH1 0.97 1.1 1 1143 62 77401 Polypharmacology Molecules Target Profile
371 MCHR1 0.85 1.1 4 1143 250 77401 Polypharmacology Molecules Target Profile
372 ADRBK1 0.85 1.1 5 1143 319 77401 Polypharmacology Molecules Target Profile
373 NPBWR1 0.79 1.1 11 1143 704 77401 Polypharmacology Molecules Target Profile
374 MPI 0.82 1.1 9 1143 578 77401 Polypharmacology Molecules Target Profile
375 BAP1 0.86 1.0 5 1143 324 77401 Polypharmacology Molecules Target Profile
376 ALDH1A1 0.73 1.0 84 1143 5527 77401 Polypharmacology Molecules Target Profile
377 MARVELD2 0.92 1.0 3 1143 200 77401 Polypharmacology Molecules Target Profile
378 ALPL 0.92 1.0 3 1143 200 77401 Polypharmacology Molecules Target Profile
379 SLC6A3 0.85 1.0 13 1143 867 77401 Polypharmacology Molecules Target Profile
380 CYP2D6 0.93 1.0 3 1143 202 77401 Polypharmacology Molecules Target Profile
381 TSHR 0.85 1.0 33 1143 2226 77401 Polypharmacology Molecules Target Profile
382 UHRF1 0.94 1.0 5 1143 348 77401 Polypharmacology Molecules Target Profile
383 MAP4K2 0.93 1.0 10 1143 696 77401 Polypharmacology Molecules Target Profile
384 SLC12A5 0.94 1.0 14 1143 979 77401 Polypharmacology Molecules Target Profile
385 GBA 0.97 1.0 3 1143 211 77401 Polypharmacology Molecules Target Profile
386 ALPPL2 0.95 1.0 8 1143 563 77401 Polypharmacology Molecules Target Profile
387 CYP2C8 0.99 0.9 1 1143 72 77401 Polypharmacology Molecules Target Profile
388 PLA2G1B 0.98 0.9 3 1143 216 77401 Polypharmacology Molecules Target Profile
389 PTBP1 0.99 0.9 31 1143 2387 77401 Polypharmacology Molecules Target Profile
390 GALR3 0.99 0.9 3 1143 233 77401 Polypharmacology Molecules Target Profile
391 KLK5 0.99 0.9 7 1143 544 77401 Polypharmacology Molecules Target Profile
392 KCNH2 0.99 0.9 8 1143 626 77401 Polypharmacology Molecules Target Profile
393 ABCC1 0.99 0.9 4 1143 317 77401 Polypharmacology Molecules Target Profile
394 DRD2 0.99 0.8 30 1143 2382 77401 Polypharmacology Molecules Target Profile
395 GAA 0.99 0.8 9 1143 719 77401 Polypharmacology Molecules Target Profile
396 CYP2C19 0.99 0.8 178 1143 14009 77401 Polypharmacology Molecules Target Profile
397 PABPC1 0.99 0.8 11 1143 891 77401 Polypharmacology Molecules Target Profile
398 BAZ2B 0.99 0.8 44 1143 3570 77401 Polypharmacology Molecules Target Profile
399 GSK3A 0.99 0.8 3 1143 256 77401 Polypharmacology Molecules Target Profile
400 ARRB1 0.99 0.8 2 1143 175 77401 Polypharmacology Molecules Target Profile
401 CDC42 0.99 0.8 1 1143 89 77401 Polypharmacology Molecules Target Profile
402 PLA2G3 0.99 0.8 2 1143 178 77401 Polypharmacology Molecules Target Profile
403 RXFP1 0.99 0.7 5 1143 462 77401 Polypharmacology Molecules Target Profile
404 CYP2C9 0.99 0.7 139 1143 12441 77401 Polypharmacology Molecules Target Profile
405 NPY2R 0.99 0.7 9 1143 860 77401 Polypharmacology Molecules Target Profile
406 NPY1R 0.99 0.7 10 1143 957 77401 Polypharmacology Molecules Target Profile
407 HTR6 0.99 0.7 1 1143 97 77401 Polypharmacology Molecules Target Profile
408 PLA2G7 0.99 0.7 8 1143 781 77401 Polypharmacology Molecules Target Profile
409 CACNA1H 0.99 0.7 21 1143 2054 77401 Polypharmacology Molecules Target Profile
410 FGF22 0.99 0.7 1 1143 103 77401 Polypharmacology Molecules Target Profile
411 APOBEC3A 0.99 0.7 2 1143 206 77401 Polypharmacology Molecules Target Profile
412 HDAC3 0.99 0.6 1 1143 112 77401 Polypharmacology Molecules Target Profile
413 KCNK9 0.99 0.6 7 1143 784 77401 Polypharmacology Molecules Target Profile
414 VCAM1 0.99 0.6 1 1143 114 77401 Polypharmacology Molecules Target Profile
415 KCNK3 0.99 0.6 5 1143 600 77401 Polypharmacology Molecules Target Profile
416 RAC1 0.99 0.6 1 1143 121 77401 Polypharmacology Molecules Target Profile
417 SIRT5 0.99 0.5 1 1143 138 77401 Polypharmacology Molecules Target Profile
418 RORC 0.99 0.5 1 1143 142 77401 Polypharmacology Molecules Target Profile
419 PTH1R 0.99 0.5 1 1143 149 77401 Polypharmacology Molecules Target Profile
420 NCF1 0.99 0.5 2 1143 298 77401 Polypharmacology Molecules Target Profile
421 CTDSP1 0.99 0.4 3 1143 459 77401 Polypharmacology Molecules Target Profile
422 GNAO1 0.99 0.4 3 1143 462 77401 Polypharmacology Molecules Target Profile
423 PLCG1 0.99 0.4 4 1143 640 77401 Polypharmacology Molecules Target Profile
424 SUMO1 0.99 0.4 1 1143 164 77401 Polypharmacology Molecules Target Profile
425 F11 0.99 0.4 1 1143 167 77401 Polypharmacology Molecules Target Profile
426 EIF4H 0.99 0.4 4 1143 675 77401 Polypharmacology Molecules Target Profile
427 MAP3K3 0.99 0.4 5 1143 898 77401 Polypharmacology Molecules Target Profile
428 PLCB3 0.99 0.4 1 1143 181 77401 Polypharmacology Molecules Target Profile
429 F12 0.99 0.2 1 1143 330 77401 Polypharmacology Molecules Target Profile
430 PSMD14 0.99 0.2 1 1143 339 77401 Polypharmacology Molecules Target Profile
431 MARK3 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
432 PKN2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
433 CYP11B2 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
434 TNKS2 0.99 0.0 0 1143 12 77401 Polypharmacology Molecules Target Profile
435 AKR1C2 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
436 PDE4C 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
437 IL8 0.99 0.0 0 1143 48 77401 Polypharmacology Molecules Target Profile
438 GABRA5 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
439 CSNK1E 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
440 SMPD1 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
441 MGLL 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
442 PIM2 0.99 0.0 0 1143 16 77401 Polypharmacology Molecules Target Profile
443 SCN5A 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
444 HTR7 0.99 0.0 0 1143 28 77401 Polypharmacology Molecules Target Profile
445 GRIN3A 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
446 MELK 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
447 ABAT 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
448 TYMS 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
449 RGS7 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
450 INSR 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
451 DYRK1A 0.99 0.0 0 1143 29 77401 Polypharmacology Molecules Target Profile
452 TGFBR2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
453 HSPA5 0.99 0.0 0 1143 32 77401 Polypharmacology Molecules Target Profile
454 CBR1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
455 GRIA2 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
456 PLEC 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
457 GABRA1 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
458 BACE1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
459 NR4A1 0.99 0.0 0 1143 55 77401 Polypharmacology Molecules Target Profile
460 CACNA1G 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
461 HRH3 0.99 0.0 0 1143 12 77401 Polypharmacology Molecules Target Profile
462 PDE10A 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
463 PTGDR2 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
464 GCK 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
465 KCNMA1 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
466 GABRA3 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
467 METAP2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
468 EPHB4 0.99 0.0 0 1143 88 77401 Polypharmacology Molecules Target Profile
469 RGS16 0.99 0.0 0 1143 12 77401 Polypharmacology Molecules Target Profile
470 PRKD1 0.99 0.0 0 1143 43 77401 Polypharmacology Molecules Target Profile
471 KDR 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
472 HDAC8 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
473 SCN9A 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
474 CYP51A1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
475 UGT1A1 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
476 NOS3 0.99 0.0 0 1143 21 77401 Polypharmacology Molecules Target Profile
477 DHFR 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
478 TOP2A 0.99 0.0 0 1143 15 77401 Polypharmacology Molecules Target Profile
479 PTPN11 0.99 0.0 0 1143 17 77401 Polypharmacology Molecules Target Profile
480 RGS8 0.99 0.0 0 1143 12 77401 Polypharmacology Molecules Target Profile
481 AKR1C3 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
482 MAPK3 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
483 MMP2 0.99 0.0 0 1143 26 77401 Polypharmacology Molecules Target Profile
484 CDK6 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
485 SLC12A1 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
486 GPR32 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
487 RCE1 0.99 0.0 0 1143 53 77401 Polypharmacology Molecules Target Profile
488 PPARA 0.99 0.0 0 1143 22 77401 Polypharmacology Molecules Target Profile
489 DYRK1B 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
490 KPNA2 0.99 0.0 0 1143 106 77401 Polypharmacology Molecules Target Profile
491 ABCC8 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
492 SLC1A1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
493 RAD51 0.99 0.0 0 1143 50 77401 Polypharmacology Molecules Target Profile
494 CGA 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
495 ATIC 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
496 GRIA1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
497 SLC7A11 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
498 TEK 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
499 MAPK15 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
500 CREBBP 0.99 0.0 0 1143 95 77401 Polypharmacology Molecules Target Profile
501 MPO 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
502 UGT2B7 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
503 GSTA2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
504 SHBG 0.99 0.0 0 1143 15 77401 Polypharmacology Molecules Target Profile
505 PTGES 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
506 ABCG2 0.99 0.0 0 1143 51 77401 Polypharmacology Molecules Target Profile
507 CCR2 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
508 BCL2L10 0.99 0.0 0 1143 23 77401 Polypharmacology Molecules Target Profile
509 APEX1 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
510 NR3C2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
511 GRM2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
512 PDE3A 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
513 DCK 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
514 BRSK2 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
515 ATP1A1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
516 RGS19 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
517 HTR1F 0.99 0.0 0 1143 17 77401 Polypharmacology Molecules Target Profile
518 AKR1C1 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
519 TRPA1 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
520 KARS 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
521 ITPKC 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
522 TOP1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
523 TNKS 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
524 GRIN2A 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
525 HDAC6 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
526 CNR1 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
527 RPS6KA3 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
528 ALOX5 0.99 0.0 0 1143 18 77401 Polypharmacology Molecules Target Profile
529 SLC47A1 0.99 0.0 0 1143 21 77401 Polypharmacology Molecules Target Profile
530 PMM2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
531 DAO 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
532 CCT2 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
533 ALB 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
534 GPER 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
535 GSTM1 0.99 0.0 0 1143 22 77401 Polypharmacology Molecules Target Profile
536 AGXT 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
537 PLAU 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
538 RPS6KA1 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
539 GRM4 0.99 0.0 0 1143 22 77401 Polypharmacology Molecules Target Profile
540 CCR4 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
541 GRIA4 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
542 CTBP1 0.99 0.0 0 1143 48 77401 Polypharmacology Molecules Target Profile
543 TMPRSS15 0.99 0.0 0 1143 17 77401 Polypharmacology Molecules Target Profile
544 CSNK1G2 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
545 TYR 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
546 TSG101 0.99 0.0 0 1143 39 77401 Polypharmacology Molecules Target Profile
547 HPRT1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
548 FPR2 0.99 0.0 0 1143 75 77401 Polypharmacology Molecules Target Profile
549 CYP11B1 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
550 AMY1C 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
551 CSNK1D 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
552 PDE4D 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
553 HRAS 0.99 0.0 0 1143 64 77401 Polypharmacology Molecules Target Profile
554 GABRR1 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
555 AKR1B1 0.99 0.0 0 1143 17 77401 Polypharmacology Molecules Target Profile
556 PIK3CA 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
557 RNASEH1 0.99 0.0 0 1143 23 77401 Polypharmacology Molecules Target Profile
558 GRIK5 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
559 NOS2 0.99 0.0 0 1143 19 77401 Polypharmacology Molecules Target Profile
560 PDE4A 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
561 TP53 0. 0.0 1143 1143 1463 77401 Polypharmacology Molecules Target Profile
562 GRIK2 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
563 PTPN1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
564 SLC47A2 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
565 MYC 0.99 0.0 0 1143 18 77401 Polypharmacology Molecules Target Profile
566 PIM1 0.99 0.0 0 1143 21 77401 Polypharmacology Molecules Target Profile
567 UGT1A9 0.99 0.0 0 1143 12 77401 Polypharmacology Molecules Target Profile
568 GSTP1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
569 ERAP1 0.99 0.0 0 1143 29 77401 Polypharmacology Molecules Target Profile
570 FLT3 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
571 SRC 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
572 EZH2 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
573 GEM 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
574 NOS1 0.99 0.0 0 1143 11 77401 Polypharmacology Molecules Target Profile
575 PIM3 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
576 SCN4A 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
577 MMP3 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
578 ERAP2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
579 ESRRG 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
580 UGT1A3 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
581 GABRA2 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
582 SCN2A 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
583 SLC12A3 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
584 HTR3A 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
585 HRH4 0.99 0.0 0 1143 16 77401 Polypharmacology Molecules Target Profile
586 HTR4 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
587 HSD17B2 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
588 ID4 0.99 0.0 0 1143 30 77401 Polypharmacology Molecules Target Profile
589 HSD11B1 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
590 FPR1 0.99 0.0 0 1143 159 77401 Polypharmacology Molecules Target Profile
591 PDE5A 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
592 NISCH 0.99 0.0 0 1143 10 77401 Polypharmacology Molecules Target Profile
593 ADH1B 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
594 DYRK3 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
595 GLO1 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
596 METAP1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
597 PDE2A 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
598 CHRNA4 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
599 CHRNA7 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
600 PDE7A 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
601 CNR2 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
602 DHODH 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
603 MMP12 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
604 SLC1A2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
605 CYP17A1 0.99 0.0 0 1143 8 77401 Polypharmacology Molecules Target Profile
606 FAAH 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
607 CYP2C18 0.99 0.0 0 1143 16 77401 Polypharmacology Molecules Target Profile
608 STK3 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
609 PRKACA 0.99 0.0 0 1143 94 77401 Polypharmacology Molecules Target Profile
610 GPBAR1 0.99 0.0 0 1143 6 77401 Polypharmacology Molecules Target Profile
611 MMP9 0.99 0.0 0 1143 14 77401 Polypharmacology Molecules Target Profile
612 CYSLTR1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
613 GRIK1 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
614 F3 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
615 RARB 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
616 HDAC2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
617 LMNA 0.99 0.0 0 1143 13 77401 Polypharmacology Molecules Target Profile
618 TTK 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
619 CHRNA2 0.99 0.0 0 1143 4 77401 Polypharmacology Molecules Target Profile
620 HSD17B1 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
621 CYP11A1 0.99 0.0 0 1143 7 77401 Polypharmacology Molecules Target Profile
622 PARP1 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile
623 DHFRP1 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
624 CCR5 0.99 0.0 0 1143 5 77401 Polypharmacology Molecules Target Profile
625 SCN10A 0.99 0.0 0 1143 9 77401 Polypharmacology Molecules Target Profile