Phenotypic Assay

Table P1. Single Targets Enriched Among Active molecules

  • kA:The number of active compounds known to target the gene
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the gene
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )
# Target (Gene) P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology
report
View
Compounds
details
View Target Profile
1 TNFSF10 3.29e-180 99.7 143 1868 65 78212 Polypharmacology Molecules Target Profile
2 TNFRSF10B 0. 55.6 309 1868 278 78212 Polypharmacology Molecules Target Profile
3 MMP14 3.54e-160 30.6 171 1868 257 78212 Polypharmacology Molecules Target Profile
4 MTOR 8.56e-147 21.7 178 1868 378 78212 Polypharmacology Molecules Target Profile
5 THPO 1.88e-40 21.7 48 1868 95 78212 Polypharmacology Molecules Target Profile
6 NCOA2 1.52e-29 17.6 38 1868 92 78212 Polypharmacology Molecules Target Profile
7 HSP90AA1 5.11e-132 17.6 175 1868 457 78212 Polypharmacology Molecules Target Profile
8 MITF 1.73e-81 16.9 109 1868 286 78212 Polypharmacology Molecules Target Profile
9 CASP3 3.44e-172 15.1 248 1868 785 78212 Polypharmacology Molecules Target Profile
10 EPAS1 7.16e-67 14.8 95 1868 283 78212 Polypharmacology Molecules Target Profile
11 SENP6 2.04e-175 13.2 272 1868 998 78212 Polypharmacology Molecules Target Profile
12 SENP7 5.75e-171 12.9 268 1868 1003 78212 Polypharmacology Molecules Target Profile
13 KLF5 6.92e-19 12.8 28 1868 93 78212 Polypharmacology Molecules Target Profile
14 NPC1 1.38e-188 11.4 321 1868 1402 78212 Polypharmacology Molecules Target Profile
15 SENP8 6.27e-156 11.2 264 1868 1130 78212 Polypharmacology Molecules Target Profile
16 APP 1.16e-117 11.1 198 1868 825 78212 Polypharmacology Molecules Target Profile
17 PPARD 2.34e-12 10.6 20 1868 80 78212 Polypharmacology Molecules Target Profile
18 RAB9A 1.89e-187 10.0 346 1868 1735 78212 Polypharmacology Molecules Target Profile
19 NCOA3 5.48e-18 9.8 31 1868 135 78212 Polypharmacology Molecules Target Profile
20 HBB 2.36e-07 9.7 12 1868 52 78212 Polypharmacology Molecules Target Profile
21 NR1H4 1.03e-15 9.1 28 1868 130 78212 Polypharmacology Molecules Target Profile
22 SMN2 1.42e-186 9.0 371 1868 2094 78212 Polypharmacology Molecules Target Profile
23 NCOA1 3.66e-09 9.0 16 1868 75 78212 Polypharmacology Molecules Target Profile
24 STAT3 1.10e-107 8.7 212 1868 1135 78212 Polypharmacology Molecules Target Profile
25 CYP19A1 8.20e-24 8.6 45 1868 224 78212 Polypharmacology Molecules Target Profile
26 PAX8 2.72e-17 8.3 33 1868 169 78212 Polypharmacology Molecules Target Profile
27 NOD2 4.44e-25 8.2 49 1868 256 78212 Polypharmacology Molecules Target Profile
28 NR0B1 1.36e-79 8.1 163 1868 914 78212 Polypharmacology Molecules Target Profile
29 ATXN2 6.89e-59 8.0 120 1868 664 78212 Polypharmacology Molecules Target Profile
30 STK33 7.36e-17 7.7 34 1868 189 78212 Polypharmacology Molecules Target Profile
31 RORC 1.79e-09 6.9 20 1868 123 78212 Polypharmacology Molecules Target Profile
32 TNF 7.36e-17 6.8 37 1868 231 78212 Polypharmacology Molecules Target Profile
33 NOD1 6.14e-30 6.7 68 1868 436 78212 Polypharmacology Molecules Target Profile
34 BLM 8.62e-16 6.7 35 1868 222 78212 Polypharmacology Molecules Target Profile
35 HSPB1 1.21e-09 6.6 21 1868 134 78212 Polypharmacology Molecules Target Profile
36 ALOX12 1.24e-06 6.6 14 1868 90 78212 Polypharmacology Molecules Target Profile
37 NFKB1 1.05e-15 6.2 37 1868 254 78212 Polypharmacology Molecules Target Profile
38 CXCR6 2.17e-08 6.2 19 1868 130 78212 Polypharmacology Molecules Target Profile
39 STAT1 1.39e-86 6.1 222 1868 1679 78212 Polypharmacology Molecules Target Profile
40 SMAD3 7.16e-67 6.1 170 1868 1261 78212 Polypharmacology Molecules Target Profile
41 XBP1 0.00013 5.9 10 1868 71 78212 Polypharmacology Molecules Target Profile
42 IDH1 1.01e-49 5.8 130 1868 991 78212 Polypharmacology Molecules Target Profile
43 ALOX15B 3.12e-11 5.7 28 1868 208 78212 Polypharmacology Molecules Target Profile
44 RORA 5.66e-54 5.7 145 1868 1142 78212 Polypharmacology Molecules Target Profile
45 CFTR 2.64e-22 5.7 58 1868 441 78212 Polypharmacology Molecules Target Profile
46 NLRP3 3.29e-12 5.6 31 1868 234 78212 Polypharmacology Molecules Target Profile
47 CASP1 6.01e-07 5.5 17 1868 130 78212 Polypharmacology Molecules Target Profile
48 MAPK1 6.95e-33 5.4 90 1868 721 78212 Polypharmacology Molecules Target Profile
49 USP1 4.62e-19 5.4 51 1868 402 78212 Polypharmacology Molecules Target Profile
50 NR5A1 2.80e-64 5.4 182 1868 1527 78212 Polypharmacology Molecules Target Profile
51 HNF4A 4.36e-10 5.2 27 1868 219 78212 Polypharmacology Molecules Target Profile
52 SNCA 3.26e-05 5.2 13 1868 105 78212 Polypharmacology Molecules Target Profile
53 NR2F2 7.33e-15 5.2 41 1868 336 78212 Polypharmacology Molecules Target Profile
54 RBBP8 1.37e-09 5.1 26 1868 215 78212 Polypharmacology Molecules Target Profile
55 HKDC1 0.00031 4.8 11 1868 97 78212 Polypharmacology Molecules Target Profile
56 VDR 6.74e-34 4.8 106 1868 977 78212 Polypharmacology Molecules Target Profile
57 TLR9 0.00033 4.7 11 1868 98 78212 Polypharmacology Molecules Target Profile
58 USP2 0.00055 4.4 11 1868 105 78212 Polypharmacology Molecules Target Profile
59 SIX1 1.26e-08 4.4 27 1868 261 78212 Polypharmacology Molecules Target Profile
60 CCR6 1.52e-06 4.4 20 1868 194 78212 Polypharmacology Molecules Target Profile
61 PPARG 3.31e-07 4.2 23 1868 230 78212 Polypharmacology Molecules Target Profile
62 AR 1.84e-11 4.0 41 1868 437 78212 Polypharmacology Molecules Target Profile
63 MLLT3 0.0021 4.0 10 1868 106 78212 Polypharmacology Molecules Target Profile
64 ADRB2 3.08e-07 3.9 25 1868 268 78212 Polypharmacology Molecules Target Profile
65 HIF1A 4.69e-14 3.9 53 1868 587 78212 Polypharmacology Molecules Target Profile
66 PAFAH1B3 0.0014 3.9 11 1868 120 78212 Polypharmacology Molecules Target Profile
67 PKM 3.08e-07 3.5 29 1868 351 78212 Polypharmacology Molecules Target Profile
68 MAPT 2.74e-42 3.4 206 1868 2787 78212 Polypharmacology Molecules Target Profile
69 ATAD5 1.49e-47 3.3 235 1868 3225 78212 Polypharmacology Molecules Target Profile
70 JAK2 5.90e-09 3.2 41 1868 540 78212 Polypharmacology Molecules Target Profile
71 GLP1R 2.40e-20 3.2 100 1868 1354 78212 Polypharmacology Molecules Target Profile
72 PADI4 0.000103 3.2 20 1868 263 78212 Polypharmacology Molecules Target Profile
73 FEN1 0.00018 3.2 19 1868 253 78212 Polypharmacology Molecules Target Profile
74 TDP2 0.0066 3.1 11 1868 150 78212 Polypharmacology Molecules Target Profile
75 GAPDH 6.18e-09 3.1 44 1868 610 78212 Polypharmacology Molecules Target Profile
76 UBE2N 0.0034 3.0 13 1868 181 78212 Polypharmacology Molecules Target Profile
77 SMARCA2 5.59e-09 3.0 46 1868 654 78212 Polypharmacology Molecules Target Profile
78 NR5A2 0.00036 3.0 19 1868 269 78212 Polypharmacology Molecules Target Profile
79 TLR3 0.0019 3.0 15 1868 214 78212 Polypharmacology Molecules Target Profile
80 LHCGR 3.29e-05 83.9 4 1868 2 78212 Polypharmacology Molecules Target Profile
81 AURKC 0.013 41.9 2 1868 2 78212 Polypharmacology Molecules Target Profile
82 CDC25A 0.013 41.9 2 1868 2 78212 Polypharmacology Molecules Target Profile
83 TACR1 0.021 27.9 2 1868 3 78212 Polypharmacology Molecules Target Profile
84 CCR5 0.021 27.9 2 1868 3 78212 Polypharmacology Molecules Target Profile
85 MAP2K1 0.021 27.9 2 1868 3 78212 Polypharmacology Molecules Target Profile
86 SMN1 0.0033 25.2 3 1868 5 78212 Polypharmacology Molecules Target Profile
87 CALM2 0.00053 24.0 4 1868 7 78212 Polypharmacology Molecules Target Profile
88 CALM1 0.00053 24.0 4 1868 7 78212 Polypharmacology Molecules Target Profile
89 YES1 0.00072 21.0 4 1868 8 78212 Polypharmacology Molecules Target Profile
90 EIF2AK2 0.0303 21.0 2 1868 4 78212 Polypharmacology Molecules Target Profile
91 CDK5 0.0303 21.0 2 1868 4 78212 Polypharmacology Molecules Target Profile
92 AURKA 0.0303 21.0 2 1868 4 78212 Polypharmacology Molecules Target Profile
93 MC5R 0.038 16.8 2 1868 5 78212 Polypharmacology Molecules Target Profile
94 AURKB 0.038 16.8 2 1868 5 78212 Polypharmacology Molecules Target Profile
95 CSNK2A1 0.038 16.8 2 1868 5 78212 Polypharmacology Molecules Target Profile
96 MAP3K5 0.0082 15.7 3 1868 8 78212 Polypharmacology Molecules Target Profile
97 CALM3 0.0017 15.3 4 1868 11 78212 Polypharmacology Molecules Target Profile
98 ERBB2 0.0017 15.3 4 1868 11 78212 Polypharmacology Molecules Target Profile
99 GALK1 1.76e-05 14.7 7 1868 20 78212 Polypharmacology Molecules Target Profile
100 ESRRA 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
101 KIF11 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
102 BRAF 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
103 MC3R 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
104 UGT1A4 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
105 TEK 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
106 SIRT1 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
107 ODC1 0.23 14.0 1 1868 3 78212 Polypharmacology Molecules Target Profile
108 TACR2 0.00072 12.3 5 1868 17 78212 Polypharmacology Molecules Target Profile
109 ARSA 0.0051 10.5 4 1868 16 78212 Polypharmacology Molecules Target Profile
110 ADRB3 0.019 10.5 3 1868 12 78212 Polypharmacology Molecules Target Profile
111 CLK3 0.071 10.5 2 1868 8 78212 Polypharmacology Molecules Target Profile
112 SLK 0.071 10.5 2 1868 8 78212 Polypharmacology Molecules Target Profile
113 CDK1 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
114 PLAU 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
115 FMO3 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
116 HPRT1 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
117 GCK 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
118 RIPK2 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
119 CSNK1G1 0.27 10.5 1 1868 4 78212 Polypharmacology Molecules Target Profile
120 FYN 0.0057 9.9 4 1868 17 78212 Polypharmacology Molecules Target Profile
121 STAT6 0.00053 9.7 6 1868 26 78212 Polypharmacology Molecules Target Profile
122 OPRD1 0.0019 9.5 5 1868 22 78212 Polypharmacology Molecules Target Profile
123 RXRA 6.59e-05 9.1 8 1868 37 78212 Polypharmacology Molecules Target Profile
124 PLIN1 0.0307 8.4 3 1868 15 78212 Polypharmacology Molecules Target Profile
125 PARK2 0.099 8.4 2 1868 10 78212 Polypharmacology Molecules Target Profile
126 LCK 0.099 8.4 2 1868 10 78212 Polypharmacology Molecules Target Profile
127 DRD5P1 0.301 8.4 1 1868 5 78212 Polypharmacology Molecules Target Profile
128 CDK2 0.301 8.4 1 1868 5 78212 Polypharmacology Molecules Target Profile
129 NQO2 0.301 8.4 1 1868 5 78212 Polypharmacology Molecules Target Profile
130 TBXAS1 0.11 7.6 2 1868 11 78212 Polypharmacology Molecules Target Profile
131 PIN1 0.11 7.6 2 1868 11 78212 Polypharmacology Molecules Target Profile
132 NFKBIA 0.0017 7.4 6 1868 34 78212 Polypharmacology Molecules Target Profile
133 PIM1 0.042 7.0 3 1868 18 78212 Polypharmacology Molecules Target Profile
134 MAPK14 0.12 7.0 2 1868 12 78212 Polypharmacology Molecules Target Profile
135 KDM4A 0.12 7.0 2 1868 12 78212 Polypharmacology Molecules Target Profile
136 CES1 0.34 7.0 1 1868 6 78212 Polypharmacology Molecules Target Profile
137 HRH2 0.0066 6.8 5 1868 31 78212 Polypharmacology Molecules Target Profile
138 GLA 0.052 6.3 3 1868 20 78212 Polypharmacology Molecules Target Profile
139 AGTR1 0.022 6.2 4 1868 27 78212 Polypharmacology Molecules Target Profile
140 SLC6A4 0.00027 6.1 9 1868 62 78212 Polypharmacology Molecules Target Profile
141 GLO1 0.37 6.0 1 1868 7 78212 Polypharmacology Molecules Target Profile
142 MAPK3 0.37 6.0 1 1868 7 78212 Polypharmacology Molecules Target Profile
143 HTR1B 0.0307 5.6 4 1868 30 78212 Polypharmacology Molecules Target Profile
144 HSPA1A 0.16 5.6 2 1868 15 78212 Polypharmacology Molecules Target Profile
145 RAD52 0.0013 5.3 8 1868 63 78212 Polypharmacology Molecules Target Profile
146 SIGMAR1 0.036 5.2 4 1868 32 78212 Polypharmacology Molecules Target Profile
147 MLL 0.079 5.2 3 1868 24 78212 Polypharmacology Molecules Target Profile
148 S100A4 0.18 5.2 2 1868 16 78212 Polypharmacology Molecules Target Profile
149 ALOX5 0.18 5.2 2 1868 16 78212 Polypharmacology Molecules Target Profile
150 HCRTR2 0.18 5.2 2 1868 16 78212 Polypharmacology Molecules Target Profile
151 PDE5A 0.409 5.2 1 1868 8 78212 Polypharmacology Molecules Target Profile
152 STK16 0.409 5.2 1 1868 8 78212 Polypharmacology Molecules Target Profile
153 EBP 0.409 5.2 1 1868 8 78212 Polypharmacology Molecules Target Profile
154 GRM5 0.409 5.2 1 1868 8 78212 Polypharmacology Molecules Target Profile
155 TNKS 0.409 5.2 1 1868 8 78212 Polypharmacology Molecules Target Profile
156 HTR1D 0.038 5.1 4 1868 33 78212 Polypharmacology Molecules Target Profile
157 CTSS 0.039 4.9 4 1868 34 78212 Polypharmacology Molecules Target Profile
158 CYP1B1 0.095 4.8 3 1868 26 78212 Polypharmacology Molecules Target Profile
159 SLC6A2 0.0029 4.7 8 1868 72 78212 Polypharmacology Molecules Target Profile
160 PTK2B 0.045 4.7 4 1868 36 78212 Polypharmacology Molecules Target Profile
161 SLC22A1 0.21 4.7 2 1868 18 78212 Polypharmacology Molecules Target Profile
162 CDC25B 0.0017 4.6 9 1868 83 78212 Polypharmacology Molecules Target Profile
163 OPRK1 0.0033 4.5 8 1868 74 78212 Polypharmacology Molecules Target Profile
164 ADRA2C 0.0307 4.4 5 1868 48 78212 Polypharmacology Molecules Target Profile
165 MPHOSPH8 0.0022 4.3 9 1868 87 78212 Polypharmacology Molecules Target Profile
166 ERG 0.23 4.2 2 1868 20 78212 Polypharmacology Molecules Target Profile
167 CHRM3 0.036 4.1 5 1868 51 78212 Polypharmacology Molecules Target Profile
168 OPRM1 0.074 4.0 4 1868 42 78212 Polypharmacology Molecules Target Profile
169 MBNL1 0.039 4.0 5 1868 53 78212 Polypharmacology Molecules Target Profile
170 PTPN22 0.077 3.9 4 1868 43 78212 Polypharmacology Molecules Target Profile
171 HTR2A 0.0045 3.9 9 1868 98 78212 Polypharmacology Molecules Target Profile
172 HTR2C 0.0082 3.8 8 1868 88 78212 Polypharmacology Molecules Target Profile
173 DRD4 0.15 3.8 3 1868 33 78212 Polypharmacology Molecules Target Profile
174 XDH 0.49 3.8 1 1868 11 78212 Polypharmacology Molecules Target Profile
175 NOX1 0.49 3.8 1 1868 11 78212 Polypharmacology Molecules Target Profile
176 TNKS2 0.49 3.8 1 1868 11 78212 Polypharmacology Molecules Target Profile
177 ADRA2B 0.045 3.7 5 1868 56 78212 Polypharmacology Molecules Target Profile
178 CHRM2 0.099 3.6 4 1868 47 78212 Polypharmacology Molecules Target Profile
179 ADRA2A 0.035 3.5 6 1868 71 78212 Polypharmacology Molecules Target Profile
180 LYPLA1 0.013 3.5 8 1868 95 78212 Polypharmacology Molecules Target Profile
181 HTR2B 0.013 3.5 8 1868 96 78212 Polypharmacology Molecules Target Profile
182 XIAP 0.52 3.5 1 1868 12 78212 Polypharmacology Molecules Target Profile
183 CNR1 0.52 3.5 1 1868 12 78212 Polypharmacology Molecules Target Profile
184 CA3 0.18 3.4 3 1868 37 78212 Polypharmacology Molecules Target Profile
185 EGFR 0.18 3.4 3 1868 37 78212 Polypharmacology Molecules Target Profile
186 ADORA3 0.068 3.4 5 1868 62 78212 Polypharmacology Molecules Target Profile
187 ADRA1D 0.11 3.4 4 1868 50 78212 Polypharmacology Molecules Target Profile
188 EYA2 0.11 3.4 4 1868 50 78212 Polypharmacology Molecules Target Profile
189 CYP2B6 0.19 3.3 3 1868 38 78212 Polypharmacology Molecules Target Profile
190 CASP7 0.045 3.3 6 1868 77 78212 Polypharmacology Molecules Target Profile
191 HTR7 0.301 3.2 2 1868 26 78212 Polypharmacology Molecules Target Profile
192 LMNA 0.55 3.2 1 1868 13 78212 Polypharmacology Molecules Target Profile
193 CLK1 0.15 3.0 4 1868 56 78212 Polypharmacology Molecules Target Profile
194 ACHE 0.23 3.0 3 1868 42 78212 Polypharmacology Molecules Target Profile
195 BCHE 0.34 3.0 2 1868 28 78212 Polypharmacology Molecules Target Profile
196 TOP2A 0.57 3.0 1 1868 14 78212 Polypharmacology Molecules Target Profile
197 ADRA1A 0.23 2.9 3 1868 43 78212 Polypharmacology Molecules Target Profile
198 HRH1 0.17 2.8 4 1868 59 78212 Polypharmacology Molecules Target Profile
199 S1PR1 0.000107 2.8 24 1868 358 78212 Polypharmacology Molecules Target Profile
200 CA6 0.26 2.8 3 1868 45 78212 Polypharmacology Molecules Target Profile
201 P4HB 0.37 2.8 2 1868 30 78212 Polypharmacology Molecules Target Profile
202 SLC22A2 0.59 2.8 1 1868 15 78212 Polypharmacology Molecules Target Profile
203 BCL2L2 0.59 2.8 1 1868 15 78212 Polypharmacology Molecules Target Profile
204 PIM2 0.59 2.8 1 1868 15 78212 Polypharmacology Molecules Target Profile
205 VCP 0.017 2.7 11 1868 172 78212 Polypharmacology Molecules Target Profile
206 NR3C1 0.0022 2.7 17 1868 267 78212 Polypharmacology Molecules Target Profile
207 CBX1 0.00012 2.7 26 1868 412 78212 Polypharmacology Molecules Target Profile
208 ATM 0.13 2.7 5 1868 79 78212 Polypharmacology Molecules Target Profile
209 ACP1 0.099 2.6 6 1868 95 78212 Polypharmacology Molecules Target Profile
210 NFE2L2 4.96e-23 2.6 159 1868 2671 78212 Polypharmacology Molecules Target Profile
211 CA5A 0.27 2.6 3 1868 48 78212 Polypharmacology Molecules Target Profile
212 KDM4C 0.39 2.6 2 1868 32 78212 Polypharmacology Molecules Target Profile
213 CA13 0.62 2.6 1 1868 16 78212 Polypharmacology Molecules Target Profile
214 KAT2A 0.0043 2.6 16 1868 260 78212 Polypharmacology Molecules Target Profile
215 ALOX15 4.52e-09 2.6 60 1868 995 78212 Polypharmacology Molecules Target Profile
216 CA7 0.28 2.6 3 1868 49 78212 Polypharmacology Molecules Target Profile
217 POLK 2.57e-05 2.6 33 1868 545 78212 Polypharmacology Molecules Target Profile
218 GPR35 0.409 2.5 2 1868 33 78212 Polypharmacology Molecules Target Profile
219 GALR2 0.00026 2.5 26 1868 433 78212 Polypharmacology Molecules Target Profile
220 PPP1CA 0.00016 2.5 28 1868 470 78212 Polypharmacology Molecules Target Profile
221 CA4 0.28 2.5 3 1868 50 78212 Polypharmacology Molecules Target Profile
222 DUSP1 0.12 2.5 6 1868 101 78212 Polypharmacology Molecules Target Profile
223 NTSR1 0.23 2.5 4 1868 68 78212 Polypharmacology Molecules Target Profile
224 PTGS1 0.301 2.5 3 1868 51 78212 Polypharmacology Molecules Target Profile
225 CYP1A1 0.301 2.5 3 1868 51 78212 Polypharmacology Molecules Target Profile
226 THRB 0.00042 2.5 26 1868 448 78212 Polypharmacology Molecules Target Profile
227 APOBEC3F 0.0045 2.4 18 1868 314 78212 Polypharmacology Molecules Target Profile
228 TLR4 0.18 2.4 5 1868 87 78212 Polypharmacology Molecules Target Profile
229 RAD54L 0.13 2.4 6 1868 105 78212 Polypharmacology Molecules Target Profile
230 GLS 0.033 2.4 11 1868 193 78212 Polypharmacology Molecules Target Profile
231 GMNN 2.48e-14 2.4 115 1868 2086 78212 Polypharmacology Molecules Target Profile
232 CYP2E1 0.32 2.4 3 1868 53 78212 Polypharmacology Molecules Target Profile
233 CA14 0.32 2.4 3 1868 53 78212 Polypharmacology Molecules Target Profile
234 TDP1 1.97e-71 2.4 932 1868 23227 78212 Polypharmacology Molecules Target Profile
235 CYP2B7P1 0.46 2.3 2 1868 36 78212 Polypharmacology Molecules Target Profile
236 MAOA 0.46 2.3 2 1868 36 78212 Polypharmacology Molecules Target Profile
237 L3MBTL1 0.0074 2.3 18 1868 332 78212 Polypharmacology Molecules Target Profile
238 MCHR1 0.021 2.3 14 1868 258 78212 Polypharmacology Molecules Target Profile
239 S1PR3 0.017 2.3 15 1868 277 78212 Polypharmacology Molecules Target Profile
240 PPP5C 0.12 2.3 7 1868 129 78212 Polypharmacology Molecules Target Profile
241 PPME1 0.0104 2.3 17 1868 316 78212 Polypharmacology Molecules Target Profile
242 DCLRE1C 0.21 2.3 5 1868 93 78212 Polypharmacology Molecules Target Profile
243 KCNH2 0.00025 2.3 33 1868 619 78212 Polypharmacology Molecules Target Profile
244 HTT 3.90e-09 2.2 81 1868 1557 78212 Polypharmacology Molecules Target Profile
245 NLRP1 0.0062 2.2 20 1868 380 78212 Polypharmacology Molecules Target Profile
246 AHR 6.65e-11 2.2 101 1868 1970 78212 Polypharmacology Molecules Target Profile
247 RGS12 0.69 2.2 1 1868 19 78212 Polypharmacology Molecules Target Profile
248 IL1B 7.08e-11 2.2 105 1868 2087 78212 Polypharmacology Molecules Target Profile
249 ADORA1 0.49 2.1 2 1868 39 78212 Polypharmacology Molecules Target Profile
250 CYP3A7 0.505 2.1 2 1868 40 78212 Polypharmacology Molecules Target Profile
251 PDE4B 0.505 2.1 2 1868 40 78212 Polypharmacology Molecules Target Profile
252 MAOB 0.72 2.1 1 1868 20 78212 Polypharmacology Molecules Target Profile
253 S1PR4 0.031 2.1 15 1868 302 78212 Polypharmacology Molecules Target Profile
254 LYPLA2 0.099 2.0 10 1868 205 78212 Polypharmacology Molecules Target Profile
255 FKBP1A 0.74 2.0 1 1868 21 78212 Polypharmacology Molecules Target Profile
256 PPARA 0.74 2.0 1 1868 21 78212 Polypharmacology Molecules Target Profile
257 POLI 0.00031 2.0 43 1868 914 78212 Polypharmacology Molecules Target Profile
258 HTR1A 0.00101 2.0 36 1868 764 78212 Polypharmacology Molecules Target Profile
259 GPR55 0.34 2.0 4 1868 85 78212 Polypharmacology Molecules Target Profile
260 NR2E3 0.035 2.0 17 1868 366 78212 Polypharmacology Molecules Target Profile
261 PAFAH2 0.0307 1.9 18 1868 389 78212 Polypharmacology Molecules Target Profile
262 AVPR1A 0.28 1.9 5 1868 108 78212 Polypharmacology Molecules Target Profile
263 MC4R 0.0027 1.9 33 1868 722 78212 Polypharmacology Molecules Target Profile
264 CA12 0.44 1.9 3 1868 66 78212 Polypharmacology Molecules Target Profile
265 DAGLB 0.74 1.9 1 1868 22 78212 Polypharmacology Molecules Target Profile
266 CYP3A4 3.23e-11 1.9 157 1868 3614 78212 Polypharmacology Molecules Target Profile
267 POLH 0.00105 1.9 41 1868 916 78212 Polypharmacology Molecules Target Profile
268 IDE 0.11 1.9 11 1868 244 78212 Polypharmacology Molecules Target Profile
269 OXTR 0.16 1.9 9 1868 200 78212 Polypharmacology Molecules Target Profile
270 PTPN7 0.37 1.9 4 1868 89 78212 Polypharmacology Molecules Target Profile
271 CA9 0.46 1.9 3 1868 67 78212 Polypharmacology Molecules Target Profile
272 APAF1 0.0104 1.9 27 1868 607 78212 Polypharmacology Molecules Target Profile
273 CTSL1 0.049 1.9 17 1868 386 78212 Polypharmacology Molecules Target Profile
274 HCRTR1 0.00032 1.8 55 1868 1281 78212 Polypharmacology Molecules Target Profile
275 CA1 0.48 1.8 3 1868 69 78212 Polypharmacology Molecules Target Profile
276 CA5B 0.59 1.8 2 1868 46 78212 Polypharmacology Molecules Target Profile
277 GSTO1 0.018 1.8 26 1868 605 78212 Polypharmacology Molecules Target Profile
278 NR1I2 0.021 1.8 25 1868 584 78212 Polypharmacology Molecules Target Profile
279 APOBEC3G 0.029 1.8 23 1868 538 78212 Polypharmacology Molecules Target Profile
280 MAPK10 0.099 1.8 14 1868 328 78212 Polypharmacology Molecules Target Profile
281 TRPV1 0.409 1.8 4 1868 94 78212 Polypharmacology Molecules Target Profile
282 MDM2 0.59 1.8 2 1868 47 78212 Polypharmacology Molecules Target Profile
283 IL8 0.59 1.8 2 1868 47 78212 Polypharmacology Molecules Target Profile
284 ABCB6 0.21 1.8 9 1868 213 78212 Polypharmacology Molecules Target Profile
285 PTPN5 0.43 1.7 4 1868 96 78212 Polypharmacology Molecules Target Profile
286 ADRB1 0.78 1.7 1 1868 24 78212 Polypharmacology Molecules Target Profile
287 ADRA1B 0.78 1.7 1 1868 24 78212 Polypharmacology Molecules Target Profile
288 DRD1 7.19e-10 1.7 178 1868 4458 78212 Polypharmacology Molecules Target Profile
289 PRNP 0.19 1.7 10 1868 241 78212 Polypharmacology Molecules Target Profile
290 CTSB 0.52 1.7 3 1868 73 78212 Polypharmacology Molecules Target Profile
291 TARDBP 6.91e-05 1.7 81 1868 2013 78212 Polypharmacology Molecules Target Profile
292 RELA 0.62 1.7 2 1868 49 78212 Polypharmacology Molecules Target Profile
293 CYP1A2 1.70e-08 1.7 159 1868 4038 78212 Polypharmacology Molecules Target Profile
294 NPSR1 0.036 1.7 25 1868 616 78212 Polypharmacology Molecules Target Profile
295 DLD 0.13 1.7 14 1868 345 78212 Polypharmacology Molecules Target Profile
296 POLB 0.0033 1.7 51 1868 1300 78212 Polypharmacology Molecules Target Profile
297 CYP3A5 0.66 1.6 2 1868 51 78212 Polypharmacology Molecules Target Profile
298 ABCB1 0.28 1.6 8 1868 205 78212 Polypharmacology Molecules Target Profile
299 KCNJ1 0.055 1.6 25 1868 647 78212 Polypharmacology Molecules Target Profile
300 GPR183 0.12 1.6 17 1868 441 78212 Polypharmacology Molecules Target Profile
301 GBA 0.301 1.6 8 1868 208 78212 Polypharmacology Molecules Target Profile
302 CA2 0.57 1.6 3 1868 78 78212 Polypharmacology Molecules Target Profile
303 HTR1E 0.021 1.6 37 1868 972 78212 Polypharmacology Molecules Target Profile
304 DRD5 0.505 1.6 4 1868 106 78212 Polypharmacology Molecules Target Profile
305 WRN 0.28 1.6 10 1868 270 78212 Polypharmacology Molecules Target Profile
306 RAPGEF3 0.59 1.6 3 1868 81 78212 Polypharmacology Molecules Target Profile
307 BCL2 0.84 1.6 1 1868 27 78212 Polypharmacology Molecules Target Profile
308 APLNR 0.36 1.5 8 1868 218 78212 Polypharmacology Molecules Target Profile
309 WEE1 0.13 1.5 20 1868 549 78212 Polypharmacology Molecules Target Profile
310 S1PR2 0.28 1.5 11 1868 308 78212 Polypharmacology Molecules Target Profile
311 TRA@ 0.505 1.5 5 1868 140 78212 Polypharmacology Molecules Target Profile
312 CTNNB1 0.43 1.5 7 1868 198 78212 Polypharmacology Molecules Target Profile
313 MMP13 0.73 1.5 2 1868 57 78212 Polypharmacology Molecules Target Profile
314 BRCA1 0.079 1.5 34 1868 982 78212 Polypharmacology Molecules Target Profile
315 PTK2 0.27 1.5 14 1868 403 78212 Polypharmacology Molecules Target Profile
316 UCHL5 0.49 1.5 6 1868 173 78212 Polypharmacology Molecules Target Profile
317 DRD3 0.0039 1.4 93 1868 2747 78212 Polypharmacology Molecules Target Profile
318 BAZ2B 0.00105 1.4 121 1868 3602 78212 Polypharmacology Molecules Target Profile
319 CHRM4 0.13 1.4 28 1868 823 78212 Polypharmacology Molecules Target Profile
320 CLK4 0.301 1.4 13 1868 382 78212 Polypharmacology Molecules Target Profile
321 RXFP1 0.28 1.4 15 1868 448 78212 Polypharmacology Molecules Target Profile
322 TRHR 0.19 1.4 25 1868 751 78212 Polypharmacology Molecules Target Profile
323 CASP6 0.61 1.4 4 1868 120 78212 Polypharmacology Molecules Target Profile
324 CDC42 0.67 1.4 3 1868 90 78212 Polypharmacology Molecules Target Profile
325 ID4 0.87 1.4 1 1868 30 78212 Polypharmacology Molecules Target Profile
326 PREPL 0.301 1.4 16 1868 490 78212 Polypharmacology Molecules Target Profile
327 KCNQ1 0.23 1.3 26 1868 813 78212 Polypharmacology Molecules Target Profile
328 ESR1 0.055 1.3 70 1868 2234 78212 Polypharmacology Molecules Target Profile
329 HTR6 0.73 1.3 3 1868 95 78212 Polypharmacology Molecules Target Profile
330 GSK3B 0.69 1.3 4 1868 128 78212 Polypharmacology Molecules Target Profile
331 MCOLN1 0.69 1.3 4 1868 128 78212 Polypharmacology Molecules Target Profile
332 BCL2A1 0.801 1.3 2 1868 64 78212 Polypharmacology Molecules Target Profile
333 C1S 0.74 1.3 3 1868 97 78212 Polypharmacology Molecules Target Profile
334 HRAS 0.81 1.3 2 1868 65 78212 Polypharmacology Molecules Target Profile
335 ROCK2 0.62 1.3 6 1868 196 78212 Polypharmacology Molecules Target Profile
336 SLC12A5 0.27 1.3 31 1868 1023 78212 Polypharmacology Molecules Target Profile
337 COPS5 0.64 1.3 6 1868 199 78212 Polypharmacology Molecules Target Profile
338 CYP2D6 0.64 1.3 6 1868 199 78212 Polypharmacology Molecules Target Profile
339 NPBWR1 0.36 1.3 22 1868 731 78212 Polypharmacology Molecules Target Profile
340 ADAM17 0.49 1.3 13 1868 432 78212 Polypharmacology Molecules Target Profile
341 MAP4K2 0.39 1.2 22 1868 740 78212 Polypharmacology Molecules Target Profile
342 HTR5A 0.505 1.2 13 1868 437 78212 Polypharmacology Molecules Target Profile
343 RGS4 0.37 1.2 23 1868 774 78212 Polypharmacology Molecules Target Profile
344 KLK7 0.44 1.2 23 1868 794 78212 Polypharmacology Molecules Target Profile
345 MBD2 0.74 1.2 5 1868 174 78212 Polypharmacology Molecules Target Profile
346 PTH1R 0.77 1.2 4 1868 140 78212 Polypharmacology Molecules Target Profile
347 LARGE 0.77 1.2 4 1868 140 78212 Polypharmacology Molecules Target Profile
348 CYP2C8 0.87 1.2 2 1868 71 78212 Polypharmacology Molecules Target Profile
349 CHRM5 0.55 1.2 18 1868 642 78212 Polypharmacology Molecules Target Profile
350 MPI 0.57 1.2 17 1868 608 78212 Polypharmacology Molecules Target Profile
351 RACGAP1 0.74 1.1 7 1868 257 78212 Polypharmacology Molecules Target Profile
352 HPGD 0.301 1.1 85 1868 3140 78212 Polypharmacology Molecules Target Profile
353 RBBP9 0.87 1.1 3 1868 112 78212 Polypharmacology Molecules Target Profile
354 PIP4K2A 0.72 1.1 14 1868 530 78212 Polypharmacology Molecules Target Profile
355 EHMT2 0.25 1.1 198 1868 7571 78212 Polypharmacology Molecules Target Profile
356 GNAS 0.87 1.1 4 1868 154 78212 Polypharmacology Molecules Target Profile
357 FGF22 0.89 1.1 3 1868 116 78212 Polypharmacology Molecules Target Profile
358 FPR1 0.87 1.1 4 1868 156 78212 Polypharmacology Molecules Target Profile
359 ALPPL2 0.81 1.1 14 1868 558 78212 Polypharmacology Molecules Target Profile
360 TAAR1 0.75 1.1 29 1868 1157 78212 Polypharmacology Molecules Target Profile
361 GAA 0.81 1.0 18 1868 725 78212 Polypharmacology Molecules Target Profile
362 ITGA4 0.87 1.0 9 1868 366 78212 Polypharmacology Molecules Target Profile
363 ADAM10 0.87 1.0 9 1868 366 78212 Polypharmacology Molecules Target Profile
364 PLA2G7 0.84 1.0 20 1868 815 78212 Polypharmacology Molecules Target Profile
365 RAC1 0.94 1.0 3 1868 123 78212 Polypharmacology Molecules Target Profile
366 ESR2 0.87 1.0 20 1868 832 78212 Polypharmacology Molecules Target Profile
367 PRMT1 0.905 1.0 22 1868 924 78212 Polypharmacology Molecules Target Profile
368 WHSC1 0.94 1.0 6 1868 253 78212 Polypharmacology Molecules Target Profile
369 SLC5A7 0.94 1.0 28 1868 1192 78212 Polypharmacology Molecules Target Profile
370 TSG101 0.99 1.0 1 1868 43 78212 Polypharmacology Molecules Target Profile
371 PRKD1 0.99 1.0 1 1868 43 78212 Polypharmacology Molecules Target Profile
372 PTGS2 0.99 1.0 1 1868 43 78212 Polypharmacology Molecules Target Profile
373 EIF2AK3 0.99 1.0 2 1868 86 78212 Polypharmacology Molecules Target Profile
374 SLC6A3 0.96 1.0 20 1868 860 78212 Polypharmacology Molecules Target Profile
375 GNA15 0.97 1.0 9 1868 391 78212 Polypharmacology Molecules Target Profile
376 GFER 0.99 1.0 58 1868 2536 78212 Polypharmacology Molecules Target Profile
377 INS 0.99 0.9 19 1868 837 78212 Polypharmacology Molecules Target Profile
378 FASN 0.99 0.9 5 1868 227 78212 Polypharmacology Molecules Target Profile
379 ATG4B 0.99 0.9 7 1868 318 78212 Polypharmacology Molecules Target Profile
380 CYP2A6 0.99 0.9 1 1868 46 78212 Polypharmacology Molecules Target Profile
381 TUBB 0.99 0.9 11 1868 511 78212 Polypharmacology Molecules Target Profile
382 CREBBP 0.99 0.9 2 1868 93 78212 Polypharmacology Molecules Target Profile
383 MRGPRX1 0.99 0.9 33 1868 1535 78212 Polypharmacology Molecules Target Profile
384 AKT1 0.99 0.9 15 1868 701 78212 Polypharmacology Molecules Target Profile
385 PAFAH1B2 0.99 0.9 13 1868 609 78212 Polypharmacology Molecules Target Profile
386 PHOSPHO1 0.99 0.9 22 1868 1031 78212 Polypharmacology Molecules Target Profile
387 PTGER2 0.99 0.9 24 1868 1148 78212 Polypharmacology Molecules Target Profile
388 TSHR 0.99 0.9 46 1868 2221 78212 Polypharmacology Molecules Target Profile
389 DNMT1 0.99 0.9 11 1868 538 78212 Polypharmacology Molecules Target Profile
390 CHRM1 0.99 0.8 20 1868 986 78212 Polypharmacology Molecules Target Profile
391 DUSP3 0.99 0.8 6 1868 300 78212 Polypharmacology Molecules Target Profile
392 BCL2L1 0.99 0.8 12 1868 602 78212 Polypharmacology Molecules Target Profile
393 ADORA2A 0.99 0.8 1 1868 51 78212 Polypharmacology Molecules Target Profile
394 MARVELD2 0.99 0.8 4 1868 204 78212 Polypharmacology Molecules Target Profile
395 GSK3A 0.99 0.8 5 1868 255 78212 Polypharmacology Molecules Target Profile
396 ALPL 0.99 0.8 4 1868 208 78212 Polypharmacology Molecules Target Profile
397 PLK1 0.99 0.8 45 1868 2363 78212 Polypharmacology Molecules Target Profile
398 DRD2 0.99 0.8 46 1868 2450 78212 Polypharmacology Molecules Target Profile
399 NR4A1 0.99 0.8 1 1868 54 78212 Polypharmacology Molecules Target Profile
400 RCE1 0.99 0.8 1 1868 54 78212 Polypharmacology Molecules Target Profile
401 KCNK3 0.99 0.8 11 1868 597 78212 Polypharmacology Molecules Target Profile
402 EPHX2 0.99 0.8 3 1868 165 78212 Polypharmacology Molecules Target Profile
403 NCF1 0.99 0.8 6 1868 331 78212 Polypharmacology Molecules Target Profile
404 ALPI 0.99 0.7 3 1868 168 78212 Polypharmacology Molecules Target Profile
405 ADRBK1 0.99 0.7 6 1868 337 78212 Polypharmacology Molecules Target Profile
406 NPY2R 0.99 0.7 16 1868 898 78212 Polypharmacology Molecules Target Profile
407 HDAC3 0.99 0.7 2 1868 115 78212 Polypharmacology Molecules Target Profile
408 YWHAG 0.99 0.7 1 1868 59 78212 Polypharmacology Molecules Target Profile
409 ALDH1A1 0.99 0.7 99 1868 5761 78212 Polypharmacology Molecules Target Profile
410 PSMD14 0.99 0.7 6 1868 357 78212 Polypharmacology Molecules Target Profile
411 MCL1 0.99 0.7 30 1868 1781 78212 Polypharmacology Molecules Target Profile
412 RAPGEF4 0.99 0.7 2 1868 121 78212 Polypharmacology Molecules Target Profile
413 ABCC1 0.99 0.7 6 1868 367 78212 Polypharmacology Molecules Target Profile
414 MAP1LC3A 0.99 0.6 9 1868 582 78212 Polypharmacology Molecules Target Profile
415 BAP1 0.99 0.6 5 1868 324 78212 Polypharmacology Molecules Target Profile
416 SELE 0.99 0.6 6 1868 396 78212 Polypharmacology Molecules Target Profile
417 NPY1R 0.99 0.6 15 1868 991 78212 Polypharmacology Molecules Target Profile
418 MCOLN3 0.99 0.6 2 1868 141 78212 Polypharmacology Molecules Target Profile
419 CYP2C19 0.99 0.6 205 1868 13982 78212 Polypharmacology Molecules Target Profile
420 FPR2 0.99 0.6 1 1868 75 78212 Polypharmacology Molecules Target Profile
421 SIRT5 0.99 0.6 2 1868 152 78212 Polypharmacology Molecules Target Profile
422 PLA2G3 0.99 0.5 3 1868 231 78212 Polypharmacology Molecules Target Profile
423 ABCG2 0.99 0.5 1 1868 78 78212 Polypharmacology Molecules Target Profile
424 GALR3 0.99 0.5 3 1868 238 78212 Polypharmacology Molecules Target Profile
425 PTBP1 0.99 0.5 31 1868 2481 78212 Polypharmacology Molecules Target Profile
426 KLK5 0.99 0.5 7 1868 571 78212 Polypharmacology Molecules Target Profile
427 CYP2C9 0.99 0.5 164 1868 12416 78212 Polypharmacology Molecules Target Profile
428 CACNA1H 0.99 0.5 25 1868 2050 78212 Polypharmacology Molecules Target Profile
429 ASAP1 0.99 0.5 1 1868 84 78212 Polypharmacology Molecules Target Profile
430 EPHB4 0.99 0.5 1 1868 87 78212 Polypharmacology Molecules Target Profile
431 SUMO1 0.99 0.5 2 1868 174 78212 Polypharmacology Molecules Target Profile
432 CTSG 0.99 0.5 1 1868 92 78212 Polypharmacology Molecules Target Profile
433 PRKACA 0.99 0.4 1 1868 93 78212 Polypharmacology Molecules Target Profile
434 UHRF1 0.99 0.4 4 1868 373 78212 Polypharmacology Molecules Target Profile
435 KCNK9 0.99 0.4 8 1868 850 78212 Polypharmacology Molecules Target Profile
436 APOBEC3A 0.99 0.4 2 1868 214 78212 Polypharmacology Molecules Target Profile
437 VCAM1 0.99 0.4 1 1868 114 78212 Polypharmacology Molecules Target Profile
438 GNAO1 0.99 0.3 4 1868 478 78212 Polypharmacology Molecules Target Profile
439 EIF4H 0.99 0.3 6 1868 721 78212 Polypharmacology Molecules Target Profile
440 PABPC1 0.99 0.3 8 1868 962 78212 Polypharmacology Molecules Target Profile
441 PLA2G1B 0.99 0.3 2 1868 244 78212 Polypharmacology Molecules Target Profile
442 PLCG1 0.99 0.3 5 1868 655 78212 Polypharmacology Molecules Target Profile
443 MAP3K3 0.99 0.3 7 1868 1101 78212 Polypharmacology Molecules Target Profile
444 CTDSP1 0.99 0.3 3 1868 488 78212 Polypharmacology Molecules Target Profile
445 F11 0.99 0.2 1 1868 168 78212 Polypharmacology Molecules Target Profile
446 PLCB3 0.99 0.2 1 1868 186 78212 Polypharmacology Molecules Target Profile
447 ARRB1 0.99 0.2 1 1868 190 78212 Polypharmacology Molecules Target Profile
448 F2 0.99 0.2 1 1868 204 78212 Polypharmacology Molecules Target Profile
449 BCL2L10 0.99 0.0 0 1868 28 78212 Polypharmacology Molecules Target Profile
450 HSPA5 0.99 0.0 0 1868 32 78212 Polypharmacology Molecules Target Profile
451 AKR1C3 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
452 GSR 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
453 NR3C2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
454 IDO1 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
455 CHRNA2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
456 GEM 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
457 PIM3 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
458 F12 0.99 0.0 0 1868 336 78212 Polypharmacology Molecules Target Profile
459 SLC1A1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
460 SLC1A2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
461 PKN2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
462 SLC12A3 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
463 PTGES 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
464 TYMS 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
465 AVPR1B 0.99 0.0 0 1868 36 78212 Polypharmacology Molecules Target Profile
466 RGS7 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
467 PLEC 0.99 0.0 0 1868 15 78212 Polypharmacology Molecules Target Profile
468 DCK 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
469 MMP3 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
470 KCNMA1 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
471 MARK3 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
472 HRH3 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
473 GRIA4 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
474 PDE7A 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
475 UGT1A1 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
476 MTNR1A 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
477 MMP2 0.99 0.0 0 1868 31 78212 Polypharmacology Molecules Target Profile
478 MELK 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
479 NQO1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
480 CACNA1G 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
481 SHBG 0.99 0.0 0 1868 15 78212 Polypharmacology Molecules Target Profile
482 DYRK1A 0.99 0.0 0 1868 29 78212 Polypharmacology Molecules Target Profile
483 AMY1C 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
484 GRM1 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
485 GRIK1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
486 CYP11B2 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
487 CYP51A1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
488 RPS6KA1 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
489 GABRR1 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
490 KDR 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
491 RAD51 0.99 0.0 0 1868 50 78212 Polypharmacology Molecules Target Profile
492 CYP2C18 0.99 0.0 0 1868 16 78212 Polypharmacology Molecules Target Profile
493 NOS3 0.99 0.0 0 1868 21 78212 Polypharmacology Molecules Target Profile
494 BACE1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
495 ABAT 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
496 SCN10A 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
497 CCT2 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
498 CES2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
499 GRM4 0.99 0.0 0 1868 22 78212 Polypharmacology Molecules Target Profile
500 ATP1A1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
501 ADH1B 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
502 GSTA2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
503 CGA 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
504 STK3 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
505 GRIA1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
506 KEAP1 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
507 ESRRG 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
508 UGT1A3 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
509 AKR1C2 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
510 PDE4D 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
511 CYSLTR1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
512 TTK 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
513 AKR1C1 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
514 TGFBR2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
515 PARP1 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
516 GRM2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
517 CCR2 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
518 HTR3A 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
519 ALB 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
520 RGS19 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
521 INSR 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
522 AKR1B1 0.99 0.0 0 1868 17 78212 Polypharmacology Molecules Target Profile
523 PDE4A 0.99 0.0 0 1868 11 78212 Polypharmacology Molecules Target Profile
524 CSNK1G2 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
525 MTHFR 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
526 CYP11B1 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
527 HSD17B1 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
528 PDE4C 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
529 ERAP1 0.99 0.0 0 1868 30 78212 Polypharmacology Molecules Target Profile
530 CHRNA7 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
531 TP53 0. 0.0 1868 1868 815 78212 Polypharmacology Molecules Target Profile
532 PDE2A 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
533 MMP9 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
534 CNR2 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
535 RPS6KA3 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
536 DHODH 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
537 TYR 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
538 MMP12 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
539 CBR1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
540 GPER 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
541 GABRA3 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
542 CYP11A1 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
543 PTPN1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
544 ITPKC 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
545 NISCH 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
546 GABRA2 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
547 DYRK1B 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
548 TOP1 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
549 CHRNA4 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
550 GRIK5 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
551 TMPRSS15 0.99 0.0 0 1868 17 78212 Polypharmacology Molecules Target Profile
552 ERAP2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
553 EZH2 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
554 HDAC8 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
555 SRC 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
556 CDK6 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
557 UGT1A9 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
558 DYRK3 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
559 HDAC6 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
560 MTNR1B 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
561 NOS2 0.99 0.0 0 1868 19 78212 Polypharmacology Molecules Target Profile
562 GPBAR1 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
563 GABRA5 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
564 DHFRP1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
565 HRH4 0.99 0.0 0 1868 16 78212 Polypharmacology Molecules Target Profile
566 KPNA2 0.99 0.0 0 1868 106 78212 Polypharmacology Molecules Target Profile
567 CCR4 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
568 CYP17A1 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
569 ABCC8 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
570 RGS16 0.99 0.0 0 1868 13 78212 Polypharmacology Molecules Target Profile
571 F3 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
572 UGT2B7 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
573 GSTP1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
574 CSNK1E 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
575 SCN4A 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
576 GRIA2 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
577 SCN2A 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
578 DAO 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
579 GRIN3A 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
580 SCN5A 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
581 GSTM1 0.99 0.0 0 1868 23 78212 Polypharmacology Molecules Target Profile
582 HDAC2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
583 KARS 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
584 SMPD1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
585 GPR32 0.99 0.0 0 1868 11 78212 Polypharmacology Molecules Target Profile
586 APEX1 0.99 0.0 0 1868 7 78212 Polypharmacology Molecules Target Profile
587 ATIC 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
588 HSD17B2 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
589 MAPK15 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
590 MPO 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
591 CSNK1D 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
592 BRSK2 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
593 RARB 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
594 RXFP2 0.99 0.0 0 1868 33 78212 Polypharmacology Molecules Target Profile
595 AGXT 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
596 HTR1F 0.99 0.0 0 1868 17 78212 Polypharmacology Molecules Target Profile
597 DHFR 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
598 FLT3 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
599 METAP1 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
600 METAP2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
601 MYC 0.99 0.0 0 1868 18 78212 Polypharmacology Molecules Target Profile
602 SLC7A11 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
603 PMM2 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
604 AOX1 0.99 0.0 0 1868 16 78212 Polypharmacology Molecules Target Profile
605 HTR4 0.99 0.0 0 1868 14 78212 Polypharmacology Molecules Target Profile
606 PDE10A 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
607 RGS8 0.99 0.0 0 1868 12 78212 Polypharmacology Molecules Target Profile
608 SLC47A2 0.99 0.0 0 1868 11 78212 Polypharmacology Molecules Target Profile
609 SCN9A 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
610 GRIN2A 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
611 TRPA1 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
612 GRIK2 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
613 FAAH 0.99 0.0 0 1868 6 78212 Polypharmacology Molecules Target Profile
614 PDE3A 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
615 PIK3CA 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
616 SLC47A1 0.99 0.0 0 1868 21 78212 Polypharmacology Molecules Target Profile
617 PTPN11 0.99 0.0 0 1868 18 78212 Polypharmacology Molecules Target Profile
618 PTGDR2 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
619 GABRA1 0.99 0.0 0 1868 10 78212 Polypharmacology Molecules Target Profile
620 RNASEH1 0.99 0.0 0 1868 23 78212 Polypharmacology Molecules Target Profile
621 HSD11B1 0.99 0.0 0 1868 9 78212 Polypharmacology Molecules Target Profile
622 NOS1 0.99 0.0 0 1868 11 78212 Polypharmacology Molecules Target Profile
623 SIRT2 0.99 0.0 0 1868 4 78212 Polypharmacology Molecules Target Profile
624 SLC12A1 0.99 0.0 0 1868 8 78212 Polypharmacology Molecules Target Profile
625 ADORA2B 0.99 0.0 0 1868 20 78212 Polypharmacology Molecules Target Profile
626 MGLL 0.99 0.0 0 1868 5 78212 Polypharmacology Molecules Target Profile
627 CTBP1 0.99 0.0 0 1868 49 78212 Polypharmacology Molecules Target Profile