Phenotypic Assay

Table P1. Single Targets Enriched Among Active molecules

  • kA:The number of active compounds known to target the gene
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the gene
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )
# Target (Gene) P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology
report
View
Compounds
details
View Target Profile
1 IDH1 0. 118.2 4099 7342 2406 227332 Polypharmacology Molecules Target Profile
2 LHCGR 3.70e-25 81.5 21 7342 8 227332 Polypharmacology Molecules Target Profile
3 CTNNB1 0. 59.8 371 7342 202 227332 Polypharmacology Molecules Target Profile
4 KLF5 0. 37.1 340 7342 297 227332 Polypharmacology Molecules Target Profile
5 HSPA1A 1.64e-43 37.0 44 7342 37 227332 Polypharmacology Molecules Target Profile
6 TACR2 2.03e-10 34.4 10 7342 9 227332 Polypharmacology Molecules Target Profile
7 MITF 0. 31.7 1321 7342 1563 227332 Polypharmacology Molecules Target Profile
8 NCOA3 0. 26.2 516 7342 655 227332 Polypharmacology Molecules Target Profile
9 JAK2 0. 25.4 970 7342 1353 227332 Polypharmacology Molecules Target Profile
10 NCOA1 3.76e-267 25.1 313 7342 402 227332 Polypharmacology Molecules Target Profile
11 EPAS1 0. 24.2 1033 7342 1529 227332 Polypharmacology Molecules Target Profile
12 PAX8 0. 23.2 1005 7342 1543 227332 Polypharmacology Molecules Target Profile
13 TUBB 0. 23.0 643 7342 946 227332 Polypharmacology Molecules Target Profile
14 CFTR 0. 22.5 1486 7342 2532 227332 Polypharmacology Molecules Target Profile
15 ATXN2 0. 21.6 1236 7342 2114 227332 Polypharmacology Molecules Target Profile
16 HIF1A 0. 21.2 580 7342 915 227332 Polypharmacology Molecules Target Profile
17 NCOA2 1.04e-248 19.6 320 7342 526 227332 Polypharmacology Molecules Target Profile
18 MTOR 8.47e-24 18.3 30 7342 51 227332 Polypharmacology Molecules Target Profile
19 SMAD3 0. 17.6 1322 7342 2805 227332 Polypharmacology Molecules Target Profile
20 RORC 1.45e-19 17.3 25 7342 45 227332 Polypharmacology Molecules Target Profile
21 THPO 2.98e-11 16.7 14 7342 26 227332 Polypharmacology Molecules Target Profile
22 OPRD1 1.65e-09 15.5 12 7342 24 227332 Polypharmacology Molecules Target Profile
23 NR5A2 0. 15.1 622 7342 1387 227332 Polypharmacology Molecules Target Profile
24 RXRA 1.21e-08 14.8 11 7342 23 227332 Polypharmacology Molecules Target Profile
25 TDP1 0. 14.3 5955 7342 52597 227332 Polypharmacology Molecules Target Profile
26 GMNN 0. 14.1 2947 7342 10320 227332 Polypharmacology Molecules Target Profile
27 APOBEC3F 2.83e-254 13.2 393 7342 968 227332 Polypharmacology Molecules Target Profile
28 TNFRSF10B 0. 13.0 999 7342 2714 227332 Polypharmacology Molecules Target Profile
29 HNF4A 2.41e-304 12.7 483 7342 1258 227332 Polypharmacology Molecules Target Profile
30 TNF 1.53e-266 12.5 425 7342 1113 227332 Polypharmacology Molecules Target Profile
31 XBP1 2.49e-61 12.3 96 7342 244 227332 Polypharmacology Molecules Target Profile
32 CXCR6 1.30e-218 12.2 351 7342 928 227332 Polypharmacology Molecules Target Profile
33 NOD2 1.76e-303 12.1 494 7342 1350 227332 Polypharmacology Molecules Target Profile
34 S1PR1 6.52e-101 11.8 163 7342 435 227332 Polypharmacology Molecules Target Profile
35 CCR6 5.15e-260 11.6 432 7342 1221 227332 Polypharmacology Molecules Target Profile
36 PPARD 1.11e-13 11.2 21 7342 58 227332 Polypharmacology Molecules Target Profile
37 NOD1 0. 10.8 710 7342 2226 227332 Polypharmacology Molecules Target Profile
38 TLR9 9.48e-107 10.8 182 7342 535 227332 Polypharmacology Molecules Target Profile
39 HSPB1 8.20e-17 10.6 27 7342 79 227332 Polypharmacology Molecules Target Profile
40 CYP19A1 6.33e-37 10.6 62 7342 183 227332 Polypharmacology Molecules Target Profile
41 APP 0. 10.6 820 7342 2675 227332 Polypharmacology Molecules Target Profile
42 NR2F2 0. 10.4 581 7342 1856 227332 Polypharmacology Molecules Target Profile
43 ADRB2 1.39e-227 10.4 401 7342 1254 227332 Polypharmacology Molecules Target Profile
44 STK33 9.34e-70 10.3 121 7342 369 227332 Polypharmacology Molecules Target Profile
45 AGTR1 2.33e-32 10.3 55 7342 167 227332 Polypharmacology Molecules Target Profile
46 PLIN1 2.25e-28 10.2 48 7342 146 227332 Polypharmacology Molecules Target Profile
47 GALK1 3.81e-14 10.2 23 7342 70 227332 Polypharmacology Molecules Target Profile
48 NR1H4 3.13e-19 10.2 32 7342 98 227332 Polypharmacology Molecules Target Profile
49 MPHOSPH8 1.05e-10 10.1 17 7342 52 227332 Polypharmacology Molecules Target Profile
50 MMP14 5.54e-102 10.1 180 7342 562 227332 Polypharmacology Molecules Target Profile
51 IL1B 0. 9.8 2912 7342 14265 227332 Polypharmacology Molecules Target Profile
52 HKDC1 7.09e-97 9.7 176 7342 577 227332 Polypharmacology Molecules Target Profile
53 NR2E3 1.88e-242 9.5 452 7342 1555 227332 Polypharmacology Molecules Target Profile
54 OPRK1 6.75e-44 9.5 79 7342 260 227332 Polypharmacology Molecules Target Profile
55 RAD52 1.03e-124 9.3 233 7342 798 227332 Polypharmacology Molecules Target Profile
56 PRNP 6.74e-170 9.0 327 7342 1176 227332 Polypharmacology Molecules Target Profile
57 RELA 5.93e-09 8.9 15 7342 52 227332 Polypharmacology Molecules Target Profile
58 NR5A1 0. 8.9 704 7342 2686 227332 Polypharmacology Molecules Target Profile
59 IL8 2.71e-10 8.6 18 7342 65 227332 Polypharmacology Molecules Target Profile
60 SLC6A4 1.04e-07 8.6 13 7342 47 227332 Polypharmacology Molecules Target Profile
61 NTSR1 1.80e-59 8.5 116 7342 429 227332 Polypharmacology Molecules Target Profile
62 TNFSF10 2.14e-91 8.4 181 7342 680 227332 Polypharmacology Molecules Target Profile
63 ADRA2C 5.44e-06 8.2 10 7342 38 227332 Polypharmacology Molecules Target Profile
64 RAD54L 1.19e-54 8.0 111 7342 437 227332 Polypharmacology Molecules Target Profile
65 S1PR4 9.26e-124 7.9 258 7342 1044 227332 Polypharmacology Molecules Target Profile
66 PAFAH1B3 2.58e-86 7.7 181 7342 740 227332 Polypharmacology Molecules Target Profile
67 TLR3 2.67e-25 7.7 51 7342 206 227332 Polypharmacology Molecules Target Profile
68 USP1 9.45e-82 7.7 172 7342 707 227332 Polypharmacology Molecules Target Profile
69 GALR2 1.14e-106 7.7 226 7342 936 227332 Polypharmacology Molecules Target Profile
70 NFKB1 6.05e-56 7.6 118 7342 490 227332 Polypharmacology Molecules Target Profile
71 ADRA2A 1.14e-05 7.4 10 7342 42 227332 Polypharmacology Molecules Target Profile
72 APOBEC3G 1.50e-206 7.3 461 7342 2066 227332 Polypharmacology Molecules Target Profile
73 MCHR1 6.75e-120 7.2 267 7342 1185 227332 Polypharmacology Molecules Target Profile
74 SLC6A2 5.79e-07 7.2 13 7342 56 227332 Polypharmacology Molecules Target Profile
75 DAGLB 1.47e-17 7.0 37 7342 164 227332 Polypharmacology Molecules Target Profile
76 ADORA3 6.36e-06 7.0 11 7342 49 227332 Polypharmacology Molecules Target Profile
77 VDR 6.42e-218 6.9 511 7342 2450 227332 Polypharmacology Molecules Target Profile
78 HTR1E 3.60e-81 6.8 187 7342 870 227332 Polypharmacology Molecules Target Profile
79 TLR4 7.51e-27 6.7 60 7342 278 227332 Polypharmacology Molecules Target Profile
80 ERG 4.61e-10 6.7 21 7342 98 227332 Polypharmacology Molecules Target Profile
81 CASP1 1.72e-44 6.6 103 7342 488 227332 Polypharmacology Molecules Target Profile
82 NPSR1 4.48e-147 6.4 363 7342 1844 227332 Polypharmacology Molecules Target Profile
83 FEN1 1.89e-92 6.3 227 7342 1144 227332 Polypharmacology Molecules Target Profile
84 AR 5.49e-32 6.3 76 7342 377 227332 Polypharmacology Molecules Target Profile
85 OPRM1 2.40e-12 6.2 28 7342 141 227332 Polypharmacology Molecules Target Profile
86 GALR3 3.57e-98 6.1 248 7342 1294 227332 Polypharmacology Molecules Target Profile
87 GPR35 3.20e-12 6.1 28 7342 143 227332 Polypharmacology Molecules Target Profile
88 HTR1A 1.93e-50 6.1 126 7342 654 227332 Polypharmacology Molecules Target Profile
89 WRN 2.52e-108 6.0 278 7342 1478 227332 Polypharmacology Molecules Target Profile
90 KCNJ1 6.15e-169 6.0 440 7342 2392 227332 Polypharmacology Molecules Target Profile
91 RBBP8 5.76e-100 5.9 259 7342 1393 227332 Polypharmacology Molecules Target Profile
92 S100A4 1.66e-11 5.9 27 7342 143 227332 Polypharmacology Molecules Target Profile
93 MAP1LC3A 8.37e-105 5.8 277 7342 1525 227332 Polypharmacology Molecules Target Profile
94 NPBWR1 1.52e-172 5.8 463 7342 2608 227332 Polypharmacology Molecules Target Profile
95 P4HB 1.59e-14 5.7 36 7342 198 227332 Polypharmacology Molecules Target Profile
96 TP53 1.71e-86 5.6 233 7342 1312 227332 Polypharmacology Molecules Target Profile
97 NR3C1 6.39e-16 5.6 40 7342 223 227332 Polypharmacology Molecules Target Profile
98 S1PR3 9.78e-30 5.6 78 7342 437 227332 Polypharmacology Molecules Target Profile
99 SIX1 1.79e-103 5.4 292 7342 1732 227332 Polypharmacology Molecules Target Profile
100 BLM 4.83e-42 5.4 116 7342 679 227332 Polypharmacology Molecules Target Profile
101 BCL2A1 1.36e-14 5.3 38 7342 221 227332 Polypharmacology Molecules Target Profile
102 HTR2A 5.58e-05 5.3 11 7342 64 227332 Polypharmacology Molecules Target Profile
103 MDM2 5.05e-12 5.3 31 7342 182 227332 Polypharmacology Molecules Target Profile
104 APLNR 1.13e-67 5.2 194 7342 1173 227332 Polypharmacology Molecules Target Profile
105 HSP90AA1 2.25e-160 5.2 474 7342 2971 227332 Polypharmacology Molecules Target Profile
106 GPR55 3.84e-25 5.2 70 7342 423 227332 Polypharmacology Molecules Target Profile
107 NFE2L2 0. 5.2 1084 7342 7388 227332 Polypharmacology Molecules Target Profile
108 MLLT3 1.21e-60 5.1 179 7342 1118 227332 Polypharmacology Molecules Target Profile
109 HTR2C 0.00022 4.9 10 7342 63 227332 Polypharmacology Molecules Target Profile
110 GLP1R 1.60e-229 4.9 736 7342 5077 227332 Polypharmacology Molecules Target Profile
111 S1PR2 3.89e-28 4.8 84 7342 543 227332 Polypharmacology Molecules Target Profile
112 MAPK1 4.26e-42 4.7 133 7342 897 227332 Polypharmacology Molecules Target Profile
113 MAP4K2 6.37e-132 4.6 435 7342 3041 227332 Polypharmacology Molecules Target Profile
114 MLL 0.00017 4.6 11 7342 74 227332 Polypharmacology Molecules Target Profile
115 VCP 2.18e-35 4.6 113 7342 774 227332 Polypharmacology Molecules Target Profile
116 MC4R 3.29e-179 4.5 613 7342 4471 227332 Polypharmacology Molecules Target Profile
117 GSTO1 2.42e-111 4.5 375 7342 2671 227332 Polypharmacology Molecules Target Profile
118 CYP2D6 1.22e-07 4.4 22 7342 154 227332 Polypharmacology Molecules Target Profile
119 BCL2 1.85e-05 4.3 15 7342 107 227332 Polypharmacology Molecules Target Profile
120 UCHL5 1.45e-34 4.3 117 7342 848 227332 Polypharmacology Molecules Target Profile
121 LARGE 7.33e-29 4.3 97 7342 703 227332 Polypharmacology Molecules Target Profile
122 ACP1 1.07e-28 4.3 97 7342 707 227332 Polypharmacology Molecules Target Profile
123 PADI4 2.59e-44 4.3 153 7342 1122 227332 Polypharmacology Molecules Target Profile
124 HTR5A 5.72e-78 4.2 278 7342 2087 227332 Polypharmacology Molecules Target Profile
125 CTSB 0.00034 4.2 11 7342 81 227332 Polypharmacology Molecules Target Profile
126 MMP2 2.73e-12 4.2 40 7342 296 227332 Polypharmacology Molecules Target Profile
127 STAT3 7.28e-122 4.2 452 7342 3526 227332 Polypharmacology Molecules Target Profile
128 NPY2R 1.07e-88 4.2 325 7342 2501 227332 Polypharmacology Molecules Target Profile
129 RGS4 2.68e-129 4.1 483 7342 3795 227332 Polypharmacology Molecules Target Profile
130 MCOLN3 7.36e-21 4.1 73 7342 558 227332 Polypharmacology Molecules Target Profile
131 UBE2N 4.16e-45 4.1 166 7342 1289 227332 Polypharmacology Molecules Target Profile
132 CHRM4 3.74e-124 4.0 477 7342 3840 227332 Polypharmacology Molecules Target Profile
133 OXTR 1.69e-37 4.0 139 7342 1091 227332 Polypharmacology Molecules Target Profile
134 NPY1R 3.87e-88 4.0 341 7342 2753 227332 Polypharmacology Molecules Target Profile
135 KCNQ1 4.51e-144 3.9 577 7342 4829 227332 Polypharmacology Molecules Target Profile
136 SNCA 4.70e-15 3.9 54 7342 428 227332 Polypharmacology Molecules Target Profile
137 GAPDH 6.14e-50 3.9 193 7342 1561 227332 Polypharmacology Molecules Target Profile
138 PPARG 7.68e-09 3.9 30 7342 239 227332 Polypharmacology Molecules Target Profile
139 DCLRE1C 9.08e-08 3.9 26 7342 208 227332 Polypharmacology Molecules Target Profile
140 KDM4C 3.40e-05 3.9 16 7342 128 227332 Polypharmacology Molecules Target Profile
141 ASAP1 1.00e-19 3.9 73 7342 588 227332 Polypharmacology Molecules Target Profile
142 ALOX15B 8.72e-15 3.9 54 7342 435 227332 Polypharmacology Molecules Target Profile
143 NLRP3 4.88e-36 3.9 139 7342 1130 227332 Polypharmacology Molecules Target Profile
144 DRD3 2.22e-260 3.8 1116 7342 10124 227332 Polypharmacology Molecules Target Profile
145 CHRM5 5.74e-92 3.8 381 7342 3259 227332 Polypharmacology Molecules Target Profile
146 NLRP1 1.81e-48 3.7 198 7342 1678 227332 Polypharmacology Molecules Target Profile
147 MAPT 4.47e-142 3.7 609 7342 5392 227332 Polypharmacology Molecules Target Profile
148 PPP1CA 4.43e-68 3.7 283 7342 2426 227332 Polypharmacology Molecules Target Profile
149 CTSL1 1.18e-38 3.6 161 7342 1392 227332 Polypharmacology Molecules Target Profile
150 ALOX12 5.13e-07 3.6 25 7342 214 227332 Polypharmacology Molecules Target Profile
151 AVPR1A 2.03e-21 3.6 87 7342 753 227332 Polypharmacology Molecules Target Profile
152 RAPGEF3 3.29e-19 3.5 79 7342 695 227332 Polypharmacology Molecules Target Profile
153 TDP2 4.19e-29 3.5 124 7342 1100 227332 Polypharmacology Molecules Target Profile
154 HTT 1.34e-147 3.5 688 7342 6515 227332 Polypharmacology Molecules Target Profile
155 RORA 1.95e-31 3.5 136 7342 1218 227332 Polypharmacology Molecules Target Profile
156 CYP1A2 5.36e-14 3.5 58 7342 520 227332 Polypharmacology Molecules Target Profile
157 THRB 2.92e-10 3.5 41 7342 367 227332 Polypharmacology Molecules Target Profile
158 RCE1 1.55e-05 3.4 20 7342 180 227332 Polypharmacology Molecules Target Profile
159 TSHR 6.94e-55 3.4 253 7342 2354 227332 Polypharmacology Molecules Target Profile
160 APAF1 7.56e-67 3.4 312 7342 2928 227332 Polypharmacology Molecules Target Profile
161 GPR183 2.44e-59 3.4 280 7342 2650 227332 Polypharmacology Molecules Target Profile
162 PKM 3.97e-22 3.3 100 7342 938 227332 Polypharmacology Molecules Target Profile
163 CBX1 1.75e-42 3.3 202 7342 1929 227332 Polypharmacology Molecules Target Profile
164 POLI 1.58e-70 3.2 360 7342 3605 227332 Polypharmacology Molecules Target Profile
165 GNAS 4.19e-13 3.1 62 7342 615 227332 Polypharmacology Molecules Target Profile
166 NCF1 8.82e-20 3.1 98 7342 987 227332 Polypharmacology Molecules Target Profile
167 SUMO1 4.94e-21 3.1 106 7342 1077 227332 Polypharmacology Molecules Target Profile
168 ABCB1 1.09e-07 3.1 35 7342 355 227332 Polypharmacology Molecules Target Profile
169 PPP5C 2.18e-10 3.0 50 7342 511 227332 Polypharmacology Molecules Target Profile
170 WHSC1 1.19e-26 3.0 143 7342 1502 227332 Polypharmacology Molecules Target Profile
171 ERAP1 4.62e-09 3.0 44 7342 458 227332 Polypharmacology Molecules Target Profile
172 CYP3A4 6.69e-13 3.0 66 7342 691 227332 Polypharmacology Molecules Target Profile
173 TSG101 0.00085 3.0 15 7342 157 227332 Polypharmacology Molecules Target Profile
174 HPRT1 0.00027 92.9 3 7342 1 227332 Polypharmacology Molecules Target Profile
175 HMGCR 0.00027 92.9 3 7342 1 227332 Polypharmacology Molecules Target Profile
176 CCNB1 3.56e-05 62.0 4 7342 2 227332 Polypharmacology Molecules Target Profile
177 KIT 0.00069 46.5 3 7342 2 227332 Polypharmacology Molecules Target Profile
178 TOP2A 6.96e-09 41.3 8 7342 6 227332 Polypharmacology Molecules Target Profile
179 MC5R 7.98e-05 41.3 4 7342 3 227332 Polypharmacology Molecules Target Profile
180 ATP1A1 0.0013 31.0 3 7342 3 227332 Polypharmacology Molecules Target Profile
181 SLC47A2 0.0013 31.0 3 7342 3 227332 Polypharmacology Molecules Target Profile
182 ESRRG 0.011 31.0 2 7342 2 227332 Polypharmacology Molecules Target Profile
183 DHFRP1 0.011 31.0 2 7342 2 227332 Polypharmacology Molecules Target Profile
184 CACNA2D1 0.0022 23.2 3 7342 4 227332 Polypharmacology Molecules Target Profile
185 CACNB2 0.0022 23.2 3 7342 4 227332 Polypharmacology Molecules Target Profile
186 ERBB2 9.93e-06 20.7 6 7342 9 227332 Polypharmacology Molecules Target Profile
187 HDAC6 0.018 20.6 2 7342 3 227332 Polypharmacology Molecules Target Profile
188 PAK4 0.018 20.6 2 7342 3 227332 Polypharmacology Molecules Target Profile
189 TERT 0.018 20.6 2 7342 3 227332 Polypharmacology Molecules Target Profile
190 GSR 0.018 20.6 2 7342 3 227332 Polypharmacology Molecules Target Profile
191 MYLK 0.018 20.6 2 7342 3 227332 Polypharmacology Molecules Target Profile
192 TBXAS1 8.00e-05 19.4 5 7342 8 227332 Polypharmacology Molecules Target Profile
193 NFKBIA 3.71e-07 19.1 8 7342 13 227332 Polypharmacology Molecules Target Profile
194 TYMS 0.0033 18.6 3 7342 5 227332 Polypharmacology Molecules Target Profile
195 CACNA1S 0.0033 18.6 3 7342 5 227332 Polypharmacology Molecules Target Profile
196 CACNA1D 0.0033 18.6 3 7342 5 227332 Polypharmacology Molecules Target Profile
197 CACNA1C 0.0033 18.6 3 7342 5 227332 Polypharmacology Molecules Target Profile
198 LCK 0.00089 15.5 4 7342 8 227332 Polypharmacology Molecules Target Profile
199 SLC22A2 0.0047 15.5 3 7342 6 227332 Polypharmacology Molecules Target Profile
200 CCR1 0.025 15.5 2 7342 4 227332 Polypharmacology Molecules Target Profile
201 HTR4 0.025 15.5 2 7342 4 227332 Polypharmacology Molecules Target Profile
202 MAP2K1 0.025 15.5 2 7342 4 227332 Polypharmacology Molecules Target Profile
203 CCR8 0.025 15.5 2 7342 4 227332 Polypharmacology Molecules Target Profile
204 YES1 0.025 15.5 2 7342 4 227332 Polypharmacology Molecules Target Profile
205 SLC47A1 0.0012 13.8 4 7342 9 227332 Polypharmacology Molecules Target Profile
206 SLC22A1 0.0066 13.3 3 7342 7 227332 Polypharmacology Molecules Target Profile
207 RNASEH1 0.0066 13.3 3 7342 7 227332 Polypharmacology Molecules Target Profile
208 FYN 4.54e-06 12.4 8 7342 20 227332 Polypharmacology Molecules Target Profile
209 AOX1 0.0017 12.4 4 7342 10 227332 Polypharmacology Molecules Target Profile
210 SMN1 0.034 12.4 2 7342 5 227332 Polypharmacology Molecules Target Profile
211 HPSE 0.034 12.4 2 7342 5 227332 Polypharmacology Molecules Target Profile
212 CCR5 0.034 12.4 2 7342 5 227332 Polypharmacology Molecules Target Profile
213 CLK3 0.034 12.4 2 7342 5 227332 Polypharmacology Molecules Target Profile
214 HBB 6.00e-06 11.8 8 7342 21 227332 Polypharmacology Molecules Target Profile
215 CALM1 0.0086 11.6 3 7342 8 227332 Polypharmacology Molecules Target Profile
216 CALM2 0.0086 11.6 3 7342 8 227332 Polypharmacology Molecules Target Profile
217 LMNA 0.0022 11.3 4 7342 11 227332 Polypharmacology Molecules Target Profile
218 NQO1 0.044 10.3 2 7342 6 227332 Polypharmacology Molecules Target Profile
219 KDR 0.044 10.3 2 7342 6 227332 Polypharmacology Molecules Target Profile
220 MAPK3 0.044 10.3 2 7342 6 227332 Polypharmacology Molecules Target Profile
221 METAP2 0.044 10.3 2 7342 6 227332 Polypharmacology Molecules Target Profile
222 MTHFR 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
223 RPS6KA1 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
224 CYTH2 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
225 PRKDC 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
226 CACNA2D2 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
227 GSTA2 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
228 TRPM8 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
229 TRPA1 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
230 TEK 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
231 MC3R 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
232 PTGER3 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
233 CBR3 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
234 DYRK3 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
235 PLA2G4A 0.17 10.3 1 7342 3 227332 Polypharmacology Molecules Target Profile
236 HK1 0.0044 8.9 4 7342 14 227332 Polypharmacology Molecules Target Profile
237 PLAU 0.0044 8.9 4 7342 14 227332 Polypharmacology Molecules Target Profile
238 PIM1 0.0044 8.9 4 7342 14 227332 Polypharmacology Molecules Target Profile
239 MGLL 0.056 8.8 2 7342 7 227332 Polypharmacology Molecules Target Profile
240 MAPK14 0.0053 8.3 4 7342 15 227332 Polypharmacology Molecules Target Profile
241 ACHE 0.00018 8.0 7 7342 27 227332 Polypharmacology Molecules Target Profile
242 RGS8 1.98e-05 8.0 9 7342 35 227332 Polypharmacology Molecules Target Profile
243 CHRM2 7.39e-05 7.7 8 7342 32 227332 Polypharmacology Molecules Target Profile
244 PIM2 0.021 7.7 3 7342 12 227332 Polypharmacology Molecules Target Profile
245 XDH 0.067 7.7 2 7342 8 227332 Polypharmacology Molecules Target Profile
246 SRC 0.067 7.7 2 7342 8 227332 Polypharmacology Molecules Target Profile
247 HRH4 0.067 7.7 2 7342 8 227332 Polypharmacology Molecules Target Profile
248 TOP1 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
249 PECR 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
250 CHEK2 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
251 PTPRK 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
252 BRSK2 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
253 MAPK15 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
254 PIK3CA 0.21 7.7 1 7342 4 227332 Polypharmacology Molecules Target Profile
255 RGS7 0.0024 7.4 5 7342 21 227332 Polypharmacology Molecules Target Profile
256 RGS16 3.47e-05 7.3 9 7342 38 227332 Polypharmacology Molecules Target Profile
257 RGS19 4.12e-05 7.2 9 7342 39 227332 Polypharmacology Molecules Target Profile
258 CALM3 0.023 7.1 3 7342 13 227332 Polypharmacology Molecules Target Profile
259 METAP1 0.078 6.9 2 7342 9 227332 Polypharmacology Molecules Target Profile
260 ADRA2B 0.00027 6.2 8 7342 40 227332 Polypharmacology Molecules Target Profile
261 CDK2 0.091 6.2 2 7342 10 227332 Polypharmacology Molecules Target Profile
262 CES2 0.091 6.2 2 7342 10 227332 Polypharmacology Molecules Target Profile
263 PDGFRB 0.26 6.2 1 7342 5 227332 Polypharmacology Molecules Target Profile
264 TACR1 0.26 6.2 1 7342 5 227332 Polypharmacology Molecules Target Profile
265 PIM3 0.26 6.2 1 7342 5 227332 Polypharmacology Molecules Target Profile
266 GEM 0.26 6.2 1 7342 5 227332 Polypharmacology Molecules Target Profile
267 STK3 0.26 6.2 1 7342 5 227332 Polypharmacology Molecules Target Profile
268 CYP3A7 0.00083 6.0 7 7342 36 227332 Polypharmacology Molecules Target Profile
269 CYP3A5 0.00048 5.6 8 7342 44 227332 Polypharmacology Molecules Target Profile
270 BCL2L2 0.00062 5.4 8 7342 46 227332 Polypharmacology Molecules Target Profile
271 DRD4 0.021 5.2 4 7342 24 227332 Polypharmacology Molecules Target Profile
272 SIGMAR1 0.048 5.2 3 7342 18 227332 Polypharmacology Molecules Target Profile
273 BRAF 0.28 5.2 1 7342 6 227332 Polypharmacology Molecules Target Profile
274 CYP11A1 0.28 5.2 1 7342 6 227332 Polypharmacology Molecules Target Profile
275 DYRK1A 0.28 5.2 1 7342 6 227332 Polypharmacology Molecules Target Profile
276 SLK 0.28 5.2 1 7342 6 227332 Polypharmacology Molecules Target Profile
277 HTR2B 0.00039 5.1 9 7342 55 227332 Polypharmacology Molecules Target Profile
278 HSPA5 0.00089 5.1 8 7342 49 227332 Polypharmacology Molecules Target Profile
279 KDM4A 0.0045 5.0 6 7342 37 227332 Polypharmacology Molecules Target Profile
280 HTR6 0.0049 4.9 6 7342 38 227332 Polypharmacology Molecules Target Profile
281 AURKB 0.13 4.8 2 7342 13 227332 Polypharmacology Molecules Target Profile
282 ADRA1D 0.013 4.7 5 7342 33 227332 Polypharmacology Molecules Target Profile
283 EGFR 0.013 4.7 5 7342 33 227332 Polypharmacology Molecules Target Profile
284 CASP9 0.0605 4.6 3 7342 20 227332 Polypharmacology Molecules Target Profile
285 STAT6 0.0605 4.6 3 7342 20 227332 Polypharmacology Molecules Target Profile
286 CHRM3 0.0037 4.4 7 7342 49 227332 Polypharmacology Molecules Target Profile
287 CNR2 0.15 4.4 2 7342 14 227332 Polypharmacology Molecules Target Profile
288 G6PD 0.017 4.3 5 7342 36 227332 Polypharmacology Molecules Target Profile
289 HRH2 0.075 4.2 3 7342 22 227332 Polypharmacology Molecules Target Profile
290 CASP8 0.039 4.1 4 7342 30 227332 Polypharmacology Molecules Target Profile
291 HTR1D 0.17 3.9 2 7342 16 227332 Polypharmacology Molecules Target Profile
292 CES1 0.17 3.9 2 7342 16 227332 Polypharmacology Molecules Target Profile
293 UGT1A1 0.35 3.9 1 7342 8 227332 Polypharmacology Molecules Target Profile
294 NQO2 0.35 3.9 1 7342 8 227332 Polypharmacology Molecules Target Profile
295 ADORA2A 0.017 3.6 6 7342 51 227332 Polypharmacology Molecules Target Profile
296 MAP3K5 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
297 IDO1 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
298 ALB 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
299 PTGER4 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
300 ARSA 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
301 SLC12A1 0.39 3.4 1 7342 9 227332 Polypharmacology Molecules Target Profile
302 CYP2A6 0.074 3.3 4 7342 38 227332 Polypharmacology Molecules Target Profile
303 CNR1 0.078 3.2 4 7342 39 227332 Polypharmacology Molecules Target Profile
304 CYP2C8 0.019 3.1 7 7342 69 227332 Polypharmacology Molecules Target Profile
305 CYP2E1 0.085 3.1 4 7342 40 227332 Polypharmacology Molecules Target Profile
306 HTR1F 0.42 3.1 1 7342 10 227332 Polypharmacology Molecules Target Profile
307 ADRB3 0.42 3.1 1 7342 10 227332 Polypharmacology Molecules Target Profile
308 IDE 1.57e-23 2.9 129 7342 1380 227332 Polypharmacology Molecules Target Profile
309 PPME1 2.43e-25 2.9 140 7342 1501 227332 Polypharmacology Molecules Target Profile
310 PLEC 0.018 2.9 8 7342 85 227332 Polypharmacology Molecules Target Profile
311 RBBP9 1.50e-07 2.9 37 7342 395 227332 Polypharmacology Molecules Target Profile
312 SELE 1.68e-13 2.9 72 7342 772 227332 Polypharmacology Molecules Target Profile
313 TMPRSS15 0.0053 2.9 11 7342 118 227332 Polypharmacology Molecules Target Profile
314 SLC5A7 4.55e-69 2.9 416 7342 4651 227332 Polypharmacology Molecules Target Profile
315 TRA@ 1.37e-19 2.9 110 7342 1204 227332 Polypharmacology Molecules Target Profile
316 ATM 5.70e-10 2.8 53 7342 580 227332 Polypharmacology Molecules Target Profile
317 L3MBTL1 4.04e-20 2.8 115 7342 1271 227332 Polypharmacology Molecules Target Profile
318 PARK2 0.44 2.8 1 7342 11 227332 Polypharmacology Molecules Target Profile
319 HCRTR1 9.23e-82 2.8 522 7342 6060 227332 Polypharmacology Molecules Target Profile
320 MCOLN1 4.67e-07 2.8 37 7342 415 227332 Polypharmacology Molecules Target Profile
321 ABCB6 2.32e-10 2.8 58 7342 653 227332 Polypharmacology Molecules Target Profile
322 CHRM1 6.69e-70 2.8 452 7342 5279 227332 Polypharmacology Molecules Target Profile
323 ATAD5 3.06e-125 2.7 880 7342 10918 227332 Polypharmacology Molecules Target Profile
324 ADAM10 4.81e-33 2.7 213 7342 2493 227332 Polypharmacology Molecules Target Profile
325 TAAR1 2.24e-84 2.7 580 7342 7039 227332 Polypharmacology Molecules Target Profile
326 COPS5 1.43e-17 2.7 109 7342 1274 227332 Polypharmacology Molecules Target Profile
327 ADORA1 0.17 2.7 3 7342 35 227332 Polypharmacology Molecules Target Profile
328 PRMT1 1.64e-51 2.7 351 7342 4224 227332 Polypharmacology Molecules Target Profile
329 PTGER2 5.67e-28 2.6 188 7342 2263 227332 Polypharmacology Molecules Target Profile
330 ADRB1 0.28 2.6 2 7342 24 227332 Polypharmacology Molecules Target Profile
331 GNA15 8.48e-32 2.6 224 7342 2760 227332 Polypharmacology Molecules Target Profile
332 PLA2G3 7.12e-22 2.6 150 7342 1839 227332 Polypharmacology Molecules Target Profile
333 MBD2 1.78e-12 2.6 82 7342 1000 227332 Polypharmacology Molecules Target Profile
334 KCNK3 8.03e-31 2.5 220 7342 2732 227332 Polypharmacology Molecules Target Profile
335 POLH 1.34e-46 2.5 343 7342 4311 227332 Polypharmacology Molecules Target Profile
336 ITGA4 1.51e-09 2.5 62 7342 765 227332 Polypharmacology Molecules Target Profile
337 RAPGEF4 1.79e-10 2.5 70 7342 871 227332 Polypharmacology Molecules Target Profile
338 PTBP1 3.00e-41 2.5 311 7342 3963 227332 Polypharmacology Molecules Target Profile
339 MPI 1.36e-24 2.5 181 7342 2298 227332 Polypharmacology Molecules Target Profile
340 GBA 1.87e-05 2.5 33 7342 415 227332 Polypharmacology Molecules Target Profile
341 CASP6 6.27e-18 2.5 129 7342 1636 227332 Polypharmacology Molecules Target Profile
342 RACGAP1 2.22e-20 2.5 149 7342 1896 227332 Polypharmacology Molecules Target Profile
343 CYP2B7P1 0.208 2.4 3 7342 38 227332 Polypharmacology Molecules Target Profile
344 PIN1 0.208 2.4 3 7342 38 227332 Polypharmacology Molecules Target Profile
345 USP2 0.0022 2.4 18 7342 231 227332 Polypharmacology Molecules Target Profile
346 DNMT1 1.29e-26 2.4 209 7342 2739 227332 Polypharmacology Molecules Target Profile
347 SENP8 6.62e-59 2.4 493 7342 6631 227332 Polypharmacology Molecules Target Profile
348 PDE4B 0.49 2.4 1 7342 13 227332 Polypharmacology Molecules Target Profile
349 MMP9 0.49 2.4 1 7342 13 227332 Polypharmacology Molecules Target Profile
350 FASN 3.22e-21 2.4 169 7342 2244 227332 Polypharmacology Molecules Target Profile
351 PDIA6 0.17 2.3 4 7342 53 227332 Polypharmacology Molecules Target Profile
352 HRH1 0.17 2.3 4 7342 53 227332 Polypharmacology Molecules Target Profile
353 SMARCA2 3.71e-30 2.3 255 7342 3458 227332 Polypharmacology Molecules Target Profile
354 CYP2B6 0.23 2.3 3 7342 40 227332 Polypharmacology Molecules Target Profile
355 STAT1 4.70e-47 2.3 418 7342 5785 227332 Polypharmacology Molecules Target Profile
356 PIP4K2A 4.20e-32 2.3 278 7342 3810 227332 Polypharmacology Molecules Target Profile
357 POLK 1.51e-15 2.3 131 7342 1790 227332 Polypharmacology Molecules Target Profile
358 PREPL 6.50e-17 2.3 143 7342 1972 227332 Polypharmacology Molecules Target Profile
359 KCNK9 1.95e-27 2.2 256 7342 3644 227332 Polypharmacology Molecules Target Profile
360 PRKD1 0.083 2.2 7 7342 98 227332 Polypharmacology Molecules Target Profile
361 PTGS1 0.24 2.2 3 7342 42 227332 Polypharmacology Molecules Target Profile
362 HTR1B 0.52 2.2 1 7342 14 227332 Polypharmacology Molecules Target Profile
363 DLD 9.29e-10 2.2 84 7342 1190 227332 Polypharmacology Molecules Target Profile
364 KCNH2 2.48e-14 2.2 131 7342 1870 227332 Polypharmacology Molecules Target Profile
365 MMP13 0.19 2.2 4 7342 57 227332 Polypharmacology Molecules Target Profile
366 PTK2B 0.11 2.2 6 7342 86 227332 Polypharmacology Molecules Target Profile
367 ADAM17 4.12e-19 2.1 185 7342 2702 227332 Polypharmacology Molecules Target Profile
368 PTK2 5.13e-06 2.1 50 7342 724 227332 Polypharmacology Molecules Target Profile
369 CTSG 0.12 2.1 6 7342 87 227332 Polypharmacology Molecules Target Profile
370 CA3 0.37 2.1 2 7342 29 227332 Polypharmacology Molecules Target Profile
371 MRGPRX1 1.64e-40 2.1 432 7342 6499 227332 Polypharmacology Molecules Target Profile
372 ATG4B 1.77e-11 2.1 110 7342 1619 227332 Polypharmacology Molecules Target Profile
373 RAD51 0.038 2.1 11 7342 161 227332 Polypharmacology Molecules Target Profile
374 LYPLA1 0.00062 2.1 30 7342 444 227332 Polypharmacology Molecules Target Profile
375 PSMD14 5.42e-13 2.1 132 7342 1980 227332 Polypharmacology Molecules Target Profile
376 GSTM1 0.032 2.1 12 7342 179 227332 Polypharmacology Molecules Target Profile
377 GLS 9.70e-06 2.1 51 7342 764 227332 Polypharmacology Molecules Target Profile
378 HDAC3 0.00091 2.1 29 7342 434 227332 Polypharmacology Molecules Target Profile
379 CYP1B1 0.38 2.1 2 7342 30 227332 Polypharmacology Molecules Target Profile
380 ADRA1B 0.54 2.1 1 7342 15 227332 Polypharmacology Molecules Target Profile
381 BCL2L10 0.073 2.0 9 7342 137 227332 Polypharmacology Molecules Target Profile
382 ALPPL2 9.61e-09 2.0 90 7342 1385 227332 Polypharmacology Molecules Target Profile
383 POLB 1.12e-20 2.0 234 7342 3640 227332 Polypharmacology Molecules Target Profile
384 BAZ2B 1.19e-61 2.0 804 7342 13175 227332 Polypharmacology Molecules Target Profile
385 SENP6 1.45e-28 2.0 351 7342 5607 227332 Polypharmacology Molecules Target Profile
386 ABCG2 0.029 2.0 14 7342 219 227332 Polypharmacology Molecules Target Profile
387 CYP1A1 0.308 2.0 3 7342 47 227332 Polypharmacology Molecules Target Profile
388 TARDBP 1.09e-28 2.0 357 7342 5730 227332 Polypharmacology Molecules Target Profile
389 CDC42 0.0039 1.9 26 7342 416 227332 Polypharmacology Molecules Target Profile
390 CDC25B 0.19 1.9 5 7342 80 227332 Polypharmacology Molecules Target Profile
391 BCHE 0.408 1.9 2 7342 32 227332 Polypharmacology Molecules Target Profile
392 ARNT 0.57 1.9 1 7342 16 227332 Polypharmacology Molecules Target Profile
393 LYPLA2 6.08e-06 1.9 67 7342 1097 227332 Polypharmacology Molecules Target Profile
394 DRD1 3.09e-45 1.9 688 7342 11881 227332 Polypharmacology Molecules Target Profile
395 YWHAG 0.21 1.9 5 7342 83 227332 Polypharmacology Molecules Target Profile
396 ALPL 0.00011 1.9 52 7342 868 227332 Polypharmacology Molecules Target Profile
397 PLK1 1.79e-38 1.9 590 7342 10208 227332 Polypharmacology Molecules Target Profile
398 PLA2G1B 4.08e-06 1.8 76 7342 1284 227332 Polypharmacology Molecules Target Profile
399 APEX1 0.59 1.8 1 7342 17 227332 Polypharmacology Molecules Target Profile
400 ALOX5 0.59 1.8 1 7342 17 227332 Polypharmacology Molecules Target Profile
401 RAC1 0.0029 1.8 34 7342 585 227332 Polypharmacology Molecules Target Profile
402 PLA2G7 1.58e-16 1.8 257 7342 4512 227332 Polypharmacology Molecules Target Profile
403 ALPI 0.00021 1.8 55 7342 962 227332 Polypharmacology Molecules Target Profile
404 EYA2 0.0203 1.8 22 7342 385 227332 Polypharmacology Molecules Target Profile
405 CASP3 2.26e-15 1.8 252 7342 4475 227332 Polypharmacology Molecules Target Profile
406 SUMO2 0.46 1.8 2 7342 35 227332 Polypharmacology Molecules Target Profile
407 PTPN22 0.1003 1.8 11 7342 193 227332 Polypharmacology Molecules Target Profile
408 MBNL1 0.208 1.8 6 7342 106 227332 Polypharmacology Molecules Target Profile
409 CTBP1 0.034 1.7 19 7342 339 227332 Polypharmacology Molecules Target Profile
410 BCL2L1 1.48e-07 1.7 118 7342 2118 227332 Polypharmacology Molecules Target Profile
411 SENP7 4.54e-17 1.7 304 7342 5564 227332 Polypharmacology Molecules Target Profile
412 ADORA2B 0.61 1.7 1 7342 18 227332 Polypharmacology Molecules Target Profile
413 GSK3B 0.0078 1.7 32 7342 579 227332 Polypharmacology Molecules Target Profile
414 SLC12A5 5.45e-12 1.7 217 7342 3995 227332 Polypharmacology Molecules Target Profile
415 CASP7 0.043 1.7 19 7342 347 227332 Polypharmacology Molecules Target Profile
416 MCL1 5.81e-17 1.7 326 7342 6103 227332 Polypharmacology Molecules Target Profile
417 NR4A1 0.27 1.7 5 7342 92 227332 Polypharmacology Molecules Target Profile
418 CTSS 0.48 1.7 2 7342 37 227332 Polypharmacology Molecules Target Profile
419 SLC6A3 0.00017 1.7 72 7342 1352 227332 Polypharmacology Molecules Target Profile
420 PMM2 0.63 1.6 1 7342 19 227332 Polypharmacology Molecules Target Profile
421 AKR1B1 0.63 1.6 1 7342 19 227332 Polypharmacology Molecules Target Profile
422 KAT2A 0.025 1.6 27 7342 516 227332 Polypharmacology Molecules Target Profile
423 CA6 0.51 1.6 2 7342 39 227332 Polypharmacology Molecules Target Profile
424 ESR1 8.32e-06 1.6 127 7342 2535 227332 Polypharmacology Molecules Target Profile
425 AHR 4.44e-13 1.5 374 7342 7731 227332 Polypharmacology Molecules Target Profile
426 MYC 0.54 1.5 2 7342 41 227332 Polypharmacology Molecules Target Profile
427 ALOX15 0.031 1.5 35 7342 726 227332 Polypharmacology Molecules Target Profile
428 PTPN7 0.208 1.5 11 7342 228 227332 Polypharmacology Molecules Target Profile
429 GCK 0.67 1.5 1 7342 21 227332 Polypharmacology Molecules Target Profile
430 HTR7 0.67 1.5 1 7342 21 227332 Polypharmacology Molecules Target Profile
431 CA13 0.67 1.5 1 7342 21 227332 Polypharmacology Molecules Target Profile
432 CACNA1H 2.14e-06 1.5 188 7342 3989 227332 Polypharmacology Molecules Target Profile
433 GSK3A 0.021 1.5 45 7342 953 227332 Polypharmacology Molecules Target Profile
434 WEE1 0.00025 1.5 115 7342 2446 227332 Polypharmacology Molecules Target Profile
435 PTPN5 0.036 1.4 39 7342 838 227332 Polypharmacology Molecules Target Profile
436 DRD2 3.17e-11 1.4 445 7342 9864 227332 Polypharmacology Molecules Target Profile
437 PAFAH2 0.00018 1.4 144 7342 3174 227332 Polypharmacology Molecules Target Profile
438 CA5A 0.58 1.4 2 7342 44 227332 Polypharmacology Molecules Target Profile
439 UHRF1 0.0014 1.4 116 7342 2601 227332 Polypharmacology Molecules Target Profile
440 CA4 0.59 1.4 2 7342 45 227332 Polypharmacology Molecules Target Profile
441 ROCK2 0.33 1.4 9 7342 203 227332 Polypharmacology Molecules Target Profile
442 PRKACA 0.48 1.4 4 7342 91 227332 Polypharmacology Molecules Target Profile
443 ALDH1A1 1.77e-11 1.4 617 7342 14414 227332 Polypharmacology Molecules Target Profile
444 MAOB 0.607 1.3 2 7342 46 227332 Polypharmacology Molecules Target Profile
445 ADRA1A 0.704 1.3 1 7342 23 227332 Polypharmacology Molecules Target Profile
446 EZH2 0.704 1.3 1 7342 23 227332 Polypharmacology Molecules Target Profile
447 EHMT2 1.17e-17 1.3 1127 7342 27182 227332 Polypharmacology Molecules Target Profile
448 NR1I2 0.014 1.3 86 7342 2003 227332 Polypharmacology Molecules Target Profile
449 ESR2 0.085 1.3 44 7342 1035 227332 Polypharmacology Molecules Target Profile
450 CA14 0.62 1.3 2 7342 48 227332 Polypharmacology Molecules Target Profile
451 HRAS 0.42 1.2 10 7342 250 227332 Polypharmacology Molecules Target Profile
452 RGS12 0.64 1.2 2 7342 50 227332 Polypharmacology Molecules Target Profile
453 GPER 0.73 1.2 1 7342 25 227332 Polypharmacology Molecules Target Profile
454 APOBEC3A 0.15 1.2 52 7342 1317 227332 Polypharmacology Molecules Target Profile
455 KPNA2 0.38 1.2 15 7342 383 227332 Polypharmacology Molecules Target Profile
456 GFER 0.00062 1.2 398 7342 10309 227332 Polypharmacology Molecules Target Profile
457 CA9 0.61 1.2 3 7342 77 227332 Polypharmacology Molecules Target Profile
458 CA12 0.61 1.2 3 7342 77 227332 Polypharmacology Molecules Target Profile
459 DRD5 0.59 1.2 4 7342 103 227332 Polypharmacology Molecules Target Profile
460 CTDSP1 0.067 1.2 111 7342 2874 227332 Polypharmacology Molecules Target Profile
461 DUSP3 0.15 1.2 68 7342 1767 227332 Polypharmacology Molecules Target Profile
462 GPR32 0.74 1.2 1 7342 26 227332 Polypharmacology Molecules Target Profile
463 TRPV1 0.33 1.2 25 7342 652 227332 Polypharmacology Molecules Target Profile
464 PABPC1 0.048 1.2 150 7342 3934 227332 Polypharmacology Molecules Target Profile
465 PTH1R 0.52 1.2 9 7342 239 227332 Polypharmacology Molecules Target Profile
466 ARRB1 0.28 1.2 40 7342 1063 227332 Polypharmacology Molecules Target Profile
467 GAA 0.208 1.2 65 7342 1733 227332 Polypharmacology Molecules Target Profile
468 MAPK10 0.47 1.2 13 7342 347 227332 Polypharmacology Molecules Target Profile
469 CA7 0.69 1.1 2 7342 54 227332 Polypharmacology Molecules Target Profile
470 ADRBK1 0.23 1.1 67 7342 1815 227332 Polypharmacology Molecules Target Profile
471 PLCG1 0.17 1.1 107 7342 2906 227332 Polypharmacology Molecules Target Profile
472 PAFAH1B2 0.11 1.1 147 7342 4002 227332 Polypharmacology Molecules Target Profile
473 INS 0.21 1.1 76 7342 2070 227332 Polypharmacology Molecules Target Profile
474 EPHB4 0.61 1.1 5 7342 137 227332 Polypharmacology Molecules Target Profile
475 CLK1 0.63 1.1 4 7342 110 227332 Polypharmacology Molecules Target Profile
476 CA1 0.68 1.1 3 7342 84 227332 Polypharmacology Molecules Target Profile
477 SMN2 0.17 1.1 186 7342 5235 227332 Polypharmacology Molecules Target Profile
478 HPGD 0.21 1.1 201 7342 5751 227332 Polypharmacology Molecules Target Profile
479 KLK7 0.48 1.0 106 7342 3146 227332 Polypharmacology Molecules Target Profile
480 TRHR 0.52 1.0 87 7342 2589 227332 Polypharmacology Molecules Target Profile
481 PHOSPHO1 0.53 1.0 100 7342 2996 227332 Polypharmacology Molecules Target Profile
482 VCAM1 0.72 1.0 5 7342 153 227332 Polypharmacology Molecules Target Profile
483 BAP1 0.704 1.0 10 7342 307 227332 Polypharmacology Molecules Target Profile
484 GNAO1 0.66 1.0 50 7342 1537 227332 Polypharmacology Molecules Target Profile
485 KEAP1 0.81 1.0 1 7342 31 227332 Polypharmacology Molecules Target Profile
486 CCT2 0.75 1.0 3 7342 93 227332 Polypharmacology Molecules Target Profile
487 EIF2AK3 0.71 1.0 11 7342 342 227332 Polypharmacology Molecules Target Profile
488 PTPN11 0.73 1.0 5 7342 156 227332 Polypharmacology Molecules Target Profile
489 DUSP1 0.77 1.0 3 7342 95 227332 Polypharmacology Molecules Target Profile
490 MARVELD2 0.75 1.0 33 7342 1052 227332 Polypharmacology Molecules Target Profile
491 GLA 0.82 1.0 1 7342 32 227332 Polypharmacology Molecules Target Profile
492 SHBG 0.82 1.0 1 7342 32 227332 Polypharmacology Molecules Target Profile
493 HCRTR2 0.79 1.0 2 7342 64 227332 Polypharmacology Molecules Target Profile
494 CYP2C9 0.99 1.0 610 7342 19561 227332 Polypharmacology Molecules Target Profile
495 MAP3K3 0.96 0.9 121 7342 3975 227332 Polypharmacology Molecules Target Profile
496 F11 0.86 0.9 13 7342 446 227332 Polypharmacology Molecules Target Profile
497 SIRT5 0.99 0.9 62 7342 2129 227332 Polypharmacology Molecules Target Profile
498 NR0B1 0.99 0.9 198 7342 6963 227332 Polypharmacology Molecules Target Profile
499 MAOA 0.88 0.9 1 7342 36 227332 Polypharmacology Molecules Target Profile
500 PLCB3 0.99 0.8 17 7342 627 227332 Polypharmacology Molecules Target Profile
501 FPR2 0.88 0.8 2 7342 74 227332 Polypharmacology Molecules Target Profile
502 EIF4H 0.99 0.8 67 7342 2570 227332 Polypharmacology Molecules Target Profile
503 BRCA1 0.99 0.8 118 7342 4603 227332 Polypharmacology Molecules Target Profile
504 CYP2C19 0.99 0.8 510 7342 19887 227332 Polypharmacology Molecules Target Profile
505 PTGS2 0.92 0.8 1 7342 40 227332 Polypharmacology Molecules Target Profile
506 KLK5 0.99 0.7 29 7342 1214 227332 Polypharmacology Molecules Target Profile
507 CA5B 0.94 0.7 1 7342 42 227332 Polypharmacology Molecules Target Profile
508 CREBBP 0.99 0.7 2 7342 89 227332 Polypharmacology Molecules Target Profile
509 FPR1 0.99 0.7 4 7342 178 227332 Polypharmacology Molecules Target Profile
510 F2 0.99 0.7 12 7342 536 227332 Polypharmacology Molecules Target Profile
511 FGF22 0.99 0.7 98 7342 4457 227332 Polypharmacology Molecules Target Profile
512 F12 0.99 0.7 16 7342 739 227332 Polypharmacology Molecules Target Profile
513 CA2 0.99 0.7 2 7342 94 227332 Polypharmacology Molecules Target Profile
514 C1S 0.99 0.7 2 7342 95 227332 Polypharmacology Molecules Target Profile
515 RAB9A 0.99 0.7 188 7342 8814 227332 Polypharmacology Molecules Target Profile
516 NPC1 0.99 0.6 155 7342 7308 227332 Polypharmacology Molecules Target Profile
517 AKT1 0.99 0.6 21 7342 1123 227332 Polypharmacology Molecules Target Profile
518 ID4 0.99 0.5 1 7342 59 227332 Polypharmacology Molecules Target Profile
519 RXFP1 0.99 0.5 12 7342 719 227332 Polypharmacology Molecules Target Profile
520 ABCC1 0.99 0.5 13 7342 830 227332 Polypharmacology Molecules Target Profile
521 EPHX2 0.99 0.3 4 7342 360 227332 Polypharmacology Molecules Target Profile
522 AKR1C2 0.99 0.0 0 7342 10 227332 Polypharmacology Molecules Target Profile
523 DHODH 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
524 CYP11B2 0.99 0.0 0 7342 12 227332 Polypharmacology Molecules Target Profile
525 AKR1C1 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
526 CAMKK2 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
527 CACNA1G 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
528 PLA2G2E 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
529 HSD11B1 0.99 0.0 0 7342 29 227332 Polypharmacology Molecules Target Profile
530 CGA 0.99 0.0 0 7342 222 227332 Polypharmacology Molecules Target Profile
531 RXFP2 0.99 0.0 0 7342 170 227332 Polypharmacology Molecules Target Profile
532 TNKS2 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
533 QPCT 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
534 SMPD1 0.99 0.0 0 7342 20 227332 Polypharmacology Molecules Target Profile
535 HCAR2 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
536 SCN10A 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
537 PTPRB 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
538 AKR1B10 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
539 PTGES 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
540 KCNMA1 0.99 0.0 0 7342 10 227332 Polypharmacology Molecules Target Profile
541 GABRA2 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
542 PDE5A 0.99 0.0 0 7342 11 227332 Polypharmacology Molecules Target Profile
543 EIF2AK2 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
544 PDE11A 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
545 UGT1A3 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
546 PDE4A 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
547 PDE10A 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
548 SCN1A 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
549 TNKS 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
550 PTPN12 0.99 0.0 0 7342 32 227332 Polypharmacology Molecules Target Profile
551 GAK 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
552 NR1H3 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
553 NR3C2 0.99 0.0 0 7342 11 227332 Polypharmacology Molecules Target Profile
554 CBR1 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
555 CYP2A13 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
556 PDE3A 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
557 SCN4A 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
558 SLC12A3 0.99 0.0 0 7342 13 227332 Polypharmacology Molecules Target Profile
559 EBP 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
560 PPARA 0.99 0.0 0 7342 17 227332 Polypharmacology Molecules Target Profile
561 MMP1 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
562 LAP3 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
563 MARK3 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
564 ELANE 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
565 AVPR1B 0.99 0.0 0 7342 193 227332 Polypharmacology Molecules Target Profile
566 SLC29A1 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
567 PDE4D 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
568 STK16 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
569 PTGDR2 0.99 0.0 0 7342 12 227332 Polypharmacology Molecules Target Profile
570 CLK4 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
571 GLO1 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
572 FLT3 0.99 0.0 0 7342 10 227332 Polypharmacology Molecules Target Profile
573 UGT1A4 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
574 MMP12 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
575 TSPO 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
576 NISCH 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
577 GRM1 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
578 FKBP1A 0.99 0.0 0 7342 27 227332 Polypharmacology Molecules Target Profile
579 F3 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
580 CYP51A1 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
581 MPO 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
582 DCK 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
583 UGT1A9 0.99 0.0 0 7342 12 227332 Polypharmacology Molecules Target Profile
584 GRM4 0.99 0.0 0 7342 24 227332 Polypharmacology Molecules Target Profile
585 HRH3 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
586 PARP1 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
587 ABCC8 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
588 PTPN6 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
589 NTSR2 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
590 PTPRF 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
591 NOX1 0.99 0.0 0 7342 40 227332 Polypharmacology Molecules Target Profile
592 PTP4A3 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
593 HSD17B3 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
594 GPBAR1 0.99 0.0 0 7342 16 227332 Polypharmacology Molecules Target Profile
595 AKR1C3 0.99 0.0 0 7342 18 227332 Polypharmacology Molecules Target Profile
596 NOS2 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
597 CYP11B1 0.99 0.0 0 7342 18 227332 Polypharmacology Molecules Target Profile
598 HSD17B2 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
599 FMO3 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
600 CSNK2A1 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
601 PGR 0.99 0.0 0 7342 17 227332 Polypharmacology Molecules Target Profile
602 GRIK2 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
603 TYR 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
604 HSD17B1 0.99 0.0 0 7342 12 227332 Polypharmacology Molecules Target Profile
605 NOS3 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
606 RET 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
607 HTR3A 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
608 SMO 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
609 MIF 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
610 CYP2C18 0.99 0.0 0 7342 14 227332 Polypharmacology Molecules Target Profile
611 BACE1 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
612 CSF1R 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
613 ACE 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
614 MMP3 0.99 0.0 0 7342 6 227332 Polypharmacology Molecules Target Profile
615 CHRNA4 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
616 FAAH 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
617 GRIA2 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
618 GRM5 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
619 NOTCH1 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
620 CYP17A1 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
621 UGT2B7 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
622 GABRA5 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
623 GABRA3 0.99 0.0 0 7342 5 227332 Polypharmacology Molecules Target Profile
624 CDC25A 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
625 MEN1 0.99 0.0 0 7342 13 227332 Polypharmacology Molecules Target Profile
626 ESRRA 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
627 ERAP2 0.99 0.0 0 7342 45 227332 Polypharmacology Molecules Target Profile
628 SCN5A 0.99 0.0 0 7342 18 227332 Polypharmacology Molecules Target Profile
629 CHRNA7 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
630 SIRT1 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
631 PLA2G2A 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
632 GABRA1 0.99 0.0 0 7342 8 227332 Polypharmacology Molecules Target Profile
633 PTGIR 0.99 0.0 0 7342 10 227332 Polypharmacology Molecules Target Profile
634 SCN9A 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
635 XIAP 0.99 0.0 0 7342 19 227332 Polypharmacology Molecules Target Profile
636 PTGDR 0.99 0.0 0 7342 7 227332 Polypharmacology Molecules Target Profile
637 PTPN1 0.99 0.0 0 7342 9 227332 Polypharmacology Molecules Target Profile
638 SIRT2 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile
639 CSNK1D 0.99 0.0 0 7342 4 227332 Polypharmacology Molecules Target Profile