Phenotypic Assay

Table P1. Single Targets Enriched Among Active molecules

  • kA:The number of active compounds known to target the gene
  • KA:The total number of active compounds(IC50 < 10-6)
  • kB:The number of inactive compounds known to target the gene
  • KB:The total number of inactive compounds(IC50 >10-6)
  • Odds Ratio: (kA/kB) / ( (KA-kA) / (KB - kB) )
# Target (Gene) P-value
FDR adjusted
Odds Ratio kA KA kB KB Polypharmacology
report
View
Compounds
details
View Target Profile
1 RXRA 8.17e-13 41.1 11 3110 17 196658 Polypharmacology Molecules Target Profile
2 LHCGR 1.26e-11 39.6 10 3110 16 196658 Polypharmacology Molecules Target Profile
3 MITF 0. 27.5 569 3110 1586 196658 Polypharmacology Molecules Target Profile
4 ATXN2 0. 26.4 525 3110 1500 196658 Polypharmacology Molecules Target Profile
5 NTSR1 6.85e-132 25.4 144 3110 375 196658 Polypharmacology Molecules Target Profile
6 THPO 3.59e-10 25.4 10 3110 25 196658 Polypharmacology Molecules Target Profile
7 PLIN1 2.41e-24 24.0 26 3110 69 196658 Polypharmacology Molecules Target Profile
8 HSPA1A 3.32e-13 22.2 14 3110 40 196658 Polypharmacology Molecules Target Profile
9 EPAS1 0. 21.7 440 3110 1480 196658 Polypharmacology Molecules Target Profile
10 HIF1A 2.44e-219 20.5 264 3110 885 196658 Polypharmacology Molecules Target Profile
11 NCOA3 1.76e-151 19.8 184 3110 624 196658 Polypharmacology Molecules Target Profile
12 MTOR 4.18e-15 19.6 17 3110 55 196658 Polypharmacology Molecules Target Profile
13 NCOA1 3.21e-87 19.2 106 3110 360 196658 Polypharmacology Molecules Target Profile
14 AGTR1 3.69e-39 19.0 47 3110 159 196658 Polypharmacology Molecules Target Profile
15 CFTR 0. 18.9 549 3110 2200 196658 Polypharmacology Molecules Target Profile
16 XBP1 1.82e-56 18.6 69 3110 239 196658 Polypharmacology Molecules Target Profile
17 KLF5 3.19e-103 18.2 129 3110 466 196658 Polypharmacology Molecules Target Profile
18 PAX8 6.89e-270 17.9 348 3110 1378 196658 Polypharmacology Molecules Target Profile
19 HSPB1 1.87e-18 17.7 22 3110 79 196658 Polypharmacology Molecules Target Profile
20 MPHOSPH8 2.85e-11 17.6 13 3110 47 196658 Polypharmacology Molecules Target Profile
21 IDH1 0. 17.4 803 3110 3865 196658 Polypharmacology Molecules Target Profile
22 RORC 6.34e-12 17.1 14 3110 52 196658 Polypharmacology Molecules Target Profile
23 SMAD3 0. 17.0 527 3110 2327 196658 Polypharmacology Molecules Target Profile
24 TNF 1.36e-204 16.7 270 3110 1110 196658 Polypharmacology Molecules Target Profile
25 OPRK1 5.84e-47 16.7 60 3110 231 196658 Polypharmacology Molecules Target Profile
26 ADORA3 3.11e-10 16.6 12 3110 46 196658 Polypharmacology Molecules Target Profile
27 GALK1 3.07e-13 16.4 16 3110 62 196658 Polypharmacology Molecules Target Profile
28 TLR9 1.31e-88 16.4 116 3110 464 196658 Polypharmacology Molecules Target Profile
29 DAGLB 2.31e-23 15.6 30 3110 123 196658 Polypharmacology Molecules Target Profile
30 NOD2 1.10e-209 15.0 293 3110 1357 196658 Polypharmacology Molecules Target Profile
31 CYP19A1 1.59e-31 14.9 42 3110 181 196658 Polypharmacology Molecules Target Profile
32 HTR2B 3.29e-08 14.4 10 3110 44 196658 Polypharmacology Molecules Target Profile
33 CCR6 1.09e-146 13.5 214 3110 1067 196658 Polypharmacology Molecules Target Profile
34 NR1H4 6.39e-15 13.5 20 3110 94 196658 Polypharmacology Molecules Target Profile
35 CXCR6 1.06e-107 13.4 157 3110 779 196658 Polypharmacology Molecules Target Profile
36 PPARD 4.15e-09 12.7 12 3110 60 196658 Polypharmacology Molecules Target Profile
37 NOD1 3.42e-249 12.3 390 3110 2262 196658 Polypharmacology Molecules Target Profile
38 ADRB2 1.59e-129 11.7 204 3110 1169 196658 Polypharmacology Molecules Target Profile
39 TMPRSS15 2.57e-11 11.7 16 3110 87 196658 Polypharmacology Molecules Target Profile
40 NCOA2 7.41e-56 10.9 90 3110 537 196658 Polypharmacology Molecules Target Profile
41 TNFRSF10B 1.47e-224 10.7 382 3110 2546 196658 Polypharmacology Molecules Target Profile
42 UBE2N 9.87e-115 10.5 192 3110 1219 196658 Polypharmacology Molecules Target Profile
43 GMNN 0. 10.5 1120 3110 9998 196658 Polypharmacology Molecules Target Profile
44 STK33 1.85e-37 10.4 61 3110 376 196658 Polypharmacology Molecules Target Profile
45 PAFAH1B3 2.97e-57 10.4 95 3110 595 196658 Polypharmacology Molecules Target Profile
46 HNF4A 1.41e-93 10.3 158 3110 1016 196658 Polypharmacology Molecules Target Profile
47 PPP1CA 9.75e-196 10.2 340 3110 2330 196658 Polypharmacology Molecules Target Profile
48 APLNR 2.67e-100 10.2 171 3110 1118 196658 Polypharmacology Molecules Target Profile
49 JAK2 7.61e-152 10.1 263 3110 1776 196658 Polypharmacology Molecules Target Profile
50 PRNP 6.27e-89 10.1 152 3110 997 196658 Polypharmacology Molecules Target Profile
51 NPSR1 2.08e-147 10.0 257 3110 1753 196658 Polypharmacology Molecules Target Profile
52 GALR2 8.46e-83 10.0 142 3110 937 196658 Polypharmacology Molecules Target Profile
53 USP2 2.46e-17 9.9 28 3110 181 196658 Polypharmacology Molecules Target Profile
54 GPR55 5.25e-36 9.8 61 3110 402 196658 Polypharmacology Molecules Target Profile
55 S1PR1 7.45e-38 9.4 66 3110 454 196658 Polypharmacology Molecules Target Profile
56 HKDC1 8.38e-39 9.3 68 3110 471 196658 Polypharmacology Molecules Target Profile
57 TLR4 9.21e-22 9.3 37 3110 254 196658 Polypharmacology Molecules Target Profile
58 SIX1 1.13e-102 9.0 190 3110 1414 196658 Polypharmacology Molecules Target Profile
59 TNFSF10 1.87e-52 8.9 96 3110 704 196658 Polypharmacology Molecules Target Profile
60 CASP1 5.60e-35 8.7 64 3110 476 196658 Polypharmacology Molecules Target Profile
61 IL1B 0. 8.6 1141 3110 12396 196658 Polypharmacology Molecules Target Profile
62 NR5A2 4.83e-87 8.6 165 3110 1272 196658 Polypharmacology Molecules Target Profile
63 NR2E3 9.61e-89 8.3 173 3110 1389 196658 Polypharmacology Molecules Target Profile
64 RBBP8 3.20e-75 8.2 147 3110 1184 196658 Polypharmacology Molecules Target Profile
65 MDM2 8.85e-12 8.1 21 3110 165 196658 Polypharmacology Molecules Target Profile
66 OPRM1 1.13e-08 8.0 15 3110 119 196658 Polypharmacology Molecules Target Profile
67 GPR35 1.35e-09 7.9 17 3110 137 196658 Polypharmacology Molecules Target Profile
68 AR 2.17e-23 7.8 45 3110 369 196658 Polypharmacology Molecules Target Profile
69 RAPGEF3 5.66e-32 7.7 63 3110 524 196658 Polypharmacology Molecules Target Profile
70 RAD52 2.43e-37 7.6 75 3110 636 196658 Polypharmacology Molecules Target Profile
71 USP1 1.46e-34 7.5 70 3110 603 196658 Polypharmacology Molecules Target Profile
72 VDR 1.63e-114 7.5 243 3110 2206 196658 Polypharmacology Molecules Target Profile
73 TDP1 0. 7.4 2082 3110 42109 196658 Polypharmacology Molecules Target Profile
74 TP53 3.28e-66 7.3 140 3110 1258 196658 Polypharmacology Molecules Target Profile
75 MMP2 9.59e-13 7.2 25 3110 222 196658 Polypharmacology Molecules Target Profile
76 HSP90AA1 1.15e-129 7.1 288 3110 2787 196658 Polypharmacology Molecules Target Profile
77 PPARG 3.96e-12 7.0 24 3110 217 196658 Polypharmacology Molecules Target Profile
78 APAF1 9.20e-118 6.8 271 3110 2738 196658 Polypharmacology Molecules Target Profile
79 SNCA 2.61e-15 6.8 32 3110 302 196658 Polypharmacology Molecules Target Profile
80 S1PR4 1.99e-46 6.7 104 3110 1012 196658 Polypharmacology Molecules Target Profile
81 APP 7.54e-117 6.7 272 3110 2788 196658 Polypharmacology Molecules Target Profile
82 MAP4K2 1.81e-123 6.6 290 3110 3011 196658 Polypharmacology Molecules Target Profile
83 DCLRE1C 2.21e-09 6.6 19 3110 184 196658 Polypharmacology Molecules Target Profile
84 PPP5C 1.30e-23 6.5 52 3110 510 196658 Polypharmacology Molecules Target Profile
85 GBA 6.89e-16 6.5 34 3110 332 196658 Polypharmacology Molecules Target Profile
86 ADAM10 3.40e-80 6.5 187 3110 1909 196658 Polypharmacology Molecules Target Profile
87 NLRP3 1.36e-47 6.5 109 3110 1090 196658 Polypharmacology Molecules Target Profile
88 KCNQ1 1.97e-169 6.4 416 3110 4620 196658 Polypharmacology Molecules Target Profile
89 MC4R 1.47e-143 6.4 350 3110 3825 196658 Polypharmacology Molecules Target Profile
90 CTNNB1 5.08e-21 6.4 47 3110 474 196658 Polypharmacology Molecules Target Profile
91 MLLT3 8.74e-38 6.3 88 3110 904 196658 Polypharmacology Molecules Target Profile
92 NR3C1 2.41e-10 6.3 22 3110 223 196658 Polypharmacology Molecules Target Profile
93 ATG4B 1.08e-53 6.1 130 3110 1389 196658 Polypharmacology Molecules Target Profile
94 PPME1 1.08e-54 6.1 133 3110 1428 196658 Polypharmacology Molecules Target Profile
95 OXTR 5.26e-42 6.1 101 3110 1075 196658 Polypharmacology Molecules Target Profile
96 HDAC3 1.01e-16 6.1 38 3110 398 196658 Polypharmacology Molecules Target Profile
97 PLA2G1B 3.31e-42 6.1 102 3110 1092 196658 Polypharmacology Molecules Target Profile
98 AVPR1A 4.82e-29 6.1 69 3110 734 196658 Polypharmacology Molecules Target Profile
99 FEN1 5.60e-35 6.1 84 3110 898 196658 Polypharmacology Molecules Target Profile
100 RGS4 3.11e-124 6.0 318 3110 3665 196658 Polypharmacology Molecules Target Profile
101 WRN 9.12e-43 6.0 105 3110 1145 196658 Polypharmacology Molecules Target Profile
102 BLM 7.77e-22 5.9 52 3110 564 196658 Polypharmacology Molecules Target Profile
103 MAPT 6.93e-158 5.9 417 3110 5033 196658 Polypharmacology Molecules Target Profile
104 ATM 2.35e-21 5.9 51 3110 556 196658 Polypharmacology Molecules Target Profile
105 MAPK1 1.34e-30 5.8 76 3110 850 196658 Polypharmacology Molecules Target Profile
106 MCHR1 6.97e-43 5.7 109 3110 1237 196658 Polypharmacology Molecules Target Profile
107 RAPGEF4 1.98e-22 5.7 55 3110 616 196658 Polypharmacology Molecules Target Profile
108 GLP1R 2.44e-132 5.7 355 3110 4328 196658 Polypharmacology Molecules Target Profile
109 ADAM17 6.62e-66 5.7 172 3110 2004 196658 Polypharmacology Molecules Target Profile
110 S1PR2 2.11e-18 5.5 46 3110 534 196658 Polypharmacology Molecules Target Profile
111 HTT 2.44e-152 5.5 431 3110 5611 196658 Polypharmacology Molecules Target Profile
112 ALOX12 8.90e-08 5.4 18 3110 211 196658 Polypharmacology Molecules Target Profile
113 NFE2L2 6.61e-166 5.3 485 3110 6576 196658 Polypharmacology Molecules Target Profile
114 MMP14 2.72e-19 5.3 50 3110 602 196658 Polypharmacology Molecules Target Profile
115 APOBEC3F 3.28e-30 5.3 81 3110 987 196658 Polypharmacology Molecules Target Profile
116 RAD54L 2.24e-13 5.3 34 3110 410 196658 Polypharmacology Molecules Target Profile
117 VCP 1.32e-21 5.2 58 3110 720 196658 Polypharmacology Molecules Target Profile
118 RCE1 4.77e-06 5.1 14 3110 173 196658 Polypharmacology Molecules Target Profile
119 BCL2A1 5.26e-07 5.0 17 3110 214 196658 Polypharmacology Molecules Target Profile
120 TUBB 3.21e-36 5.0 103 3110 1327 196658 Polypharmacology Molecules Target Profile
121 NR2F2 5.10e-44 5.0 128 3110 1680 196658 Polypharmacology Molecules Target Profile
122 IDE 8.25e-35 4.9 101 3110 1331 196658 Polypharmacology Molecules Target Profile
123 CYP1A2 6.76e-13 4.9 35 3110 454 196658 Polypharmacology Molecules Target Profile
124 NCF1 2.89e-23 4.9 66 3110 864 196658 Polypharmacology Molecules Target Profile
125 ACP1 1.57e-14 4.9 40 3110 521 196658 Polypharmacology Molecules Target Profile
126 THRB 7.48e-10 4.9 26 3110 338 196658 Polypharmacology Molecules Target Profile
127 COPS5 2.91e-25 4.9 73 3110 969 196658 Polypharmacology Molecules Target Profile
128 S1PR3 4.72e-12 4.8 33 3110 435 196658 Polypharmacology Molecules Target Profile
129 HTR5A 2.73e-46 4.8 139 3110 1884 196658 Polypharmacology Molecules Target Profile
130 GPR183 3.37e-52 4.8 159 3110 2184 196658 Polypharmacology Molecules Target Profile
131 TSHR 5.68e-51 4.7 157 3110 2181 196658 Polypharmacology Molecules Target Profile
132 HTR1A 4.75e-17 4.7 49 3110 663 196658 Polypharmacology Molecules Target Profile
133 EYA2 3.43e-08 4.7 22 3110 299 196658 Polypharmacology Molecules Target Profile
134 NR5A1 3.50e-57 4.6 181 3110 2581 196658 Polypharmacology Molecules Target Profile
135 UCHL5 8.80e-18 4.6 53 3110 741 196658 Polypharmacology Molecules Target Profile
136 ABCB1 5.25e-08 4.6 22 3110 307 196658 Polypharmacology Molecules Target Profile
137 P4HB 0.00016 4.5 11 3110 154 196658 Polypharmacology Molecules Target Profile
138 ASAP1 2.85e-11 4.5 33 3110 468 196658 Polypharmacology Molecules Target Profile
139 MAP1LC3A 1.64e-32 4.5 104 3110 1511 196658 Polypharmacology Molecules Target Profile
140 NLRP1 7.31e-35 4.5 112 3110 1631 196658 Polypharmacology Molecules Target Profile
141 L3MBTL1 3.28e-25 4.4 80 3110 1164 196658 Polypharmacology Molecules Target Profile
142 NPY2R 7.36e-49 4.4 162 3110 2416 196658 Polypharmacology Molecules Target Profile
143 PADI4 3.77e-24 4.4 78 3110 1156 196658 Polypharmacology Molecules Target Profile
144 FASN 6.23e-35 4.3 116 3110 1742 196658 Polypharmacology Molecules Target Profile
145 CYP3A4 4.28e-14 4.3 44 3110 649 196658 Polypharmacology Molecules Target Profile
146 NPBWR1 4.12e-51 4.3 174 3110 2659 196658 Polypharmacology Molecules Target Profile
147 DRD3 1.17e-133 4.3 493 3110 8306 196658 Polypharmacology Molecules Target Profile
148 SUMO1 1.92e-17 4.3 56 3110 841 196658 Polypharmacology Molecules Target Profile
149 PTGER2 6.17e-36 4.1 128 3110 2046 196658 Polypharmacology Molecules Target Profile
150 CHRM4 1.41e-54 4.1 200 3110 3265 196658 Polypharmacology Molecules Target Profile
151 ABCB6 5.60e-11 4.0 36 3110 568 196658 Polypharmacology Molecules Target Profile
152 HCRTR1 9.27e-88 4.0 338 3110 5810 196658 Polypharmacology Molecules Target Profile
153 PLA2G7 1.31e-66 4.0 252 3110 4237 196658 Polypharmacology Molecules Target Profile
154 PREPL 1.05e-31 4.0 116 3110 1904 196658 Polypharmacology Molecules Target Profile
155 PLA2G3 3.70e-26 3.9 95 3110 1558 196658 Polypharmacology Molecules Target Profile
156 PSMD14 6.49e-28 3.9 102 3110 1678 196658 Polypharmacology Molecules Target Profile
157 NPY1R 1.00e-41 3.9 158 3110 2656 196658 Polypharmacology Molecules Target Profile
158 KCNJ1 4.18e-37 3.9 141 3110 2381 196658 Polypharmacology Molecules Target Profile
159 CASP7 8.15e-06 3.9 18 3110 296 196658 Polypharmacology Molecules Target Profile
160 CBX1 1.41e-23 3.7 91 3110 1577 196658 Polypharmacology Molecules Target Profile
161 ALOX15B 2.54e-07 3.7 25 3110 429 196658 Polypharmacology Molecules Target Profile
162 BAZ2B 2.50e-137 3.7 618 3110 12356 196658 Polypharmacology Molecules Target Profile
163 GAPDH 6.12e-22 3.7 86 3110 1514 196658 Polypharmacology Molecules Target Profile
164 KAT2A 1.97e-07 3.6 26 3110 454 196658 Polypharmacology Molecules Target Profile
165 ITGA4 3.14e-11 3.6 42 3110 738 196658 Polypharmacology Molecules Target Profile
166 GNA15 4.94e-31 3.6 127 3110 2287 196658 Polypharmacology Molecules Target Profile
167 MCOLN3 4.62e-08 3.6 29 3110 512 196658 Polypharmacology Molecules Target Profile
168 ABCG2 0.0018 3.6 10 3110 177 196658 Polypharmacology Molecules Target Profile
169 POLH 2.69e-43 3.5 188 3110 3527 196658 Polypharmacology Molecules Target Profile
170 TRA@ 2.28e-13 3.5 54 3110 993 196658 Polypharmacology Molecules Target Profile
171 GSTO1 7.75e-35 3.5 152 3110 2870 196658 Polypharmacology Molecules Target Profile
172 TAAR1 5.51e-64 3.5 292 3110 5708 196658 Polypharmacology Molecules Target Profile
173 APOBEC3G 2.08e-25 3.5 109 3110 2046 196658 Polypharmacology Molecules Target Profile
174 KCNK9 2.58e-40 3.4 180 3110 3451 196658 Polypharmacology Molecules Target Profile
175 GALR3 8.57e-15 3.4 63 3110 1197 196658 Polypharmacology Molecules Target Profile
176 HTR1E 1.80e-11 3.3 48 3110 917 196658 Polypharmacology Molecules Target Profile
177 CTBP1 0.00037 3.3 14 3110 267 196658 Polypharmacology Molecules Target Profile
178 DNMT1 3.63e-24 3.3 110 3110 2161 196658 Polypharmacology Molecules Target Profile
179 ALPL 8.41e-10 3.3 41 3110 794 196658 Polypharmacology Molecules Target Profile
180 ATAD5 2.31e-90 3.2 470 3110 10223 196658 Polypharmacology Molecules Target Profile
181 RBBP9 7.51e-05 3.2 18 3110 353 196658 Polypharmacology Molecules Target Profile
182 BAP1 0.00061 3.2 14 3110 280 196658 Polypharmacology Molecules Target Profile
183 NFKB1 4.66e-06 3.1 25 3110 509 196658 Polypharmacology Molecules Target Profile
184 CHRM5 7.43e-27 3.1 136 3110 2871 196658 Polypharmacology Molecules Target Profile
185 DLD 7.66e-11 3.1 51 3110 1063 196658 Polypharmacology Molecules Target Profile
186 LYPLA1 5.46e-05 3.0 21 3110 447 196658 Polypharmacology Molecules Target Profile
187 HPRT1 4.02e-05 189.9 3 3110 1 196658 Polypharmacology Molecules Target Profile
188 ERBB2 9.06e-09 95.0 6 3110 4 196658 Polypharmacology Molecules Target Profile
189 LCK 1.93e-08 76.0 6 3110 5 196658 Polypharmacology Molecules Target Profile
190 EBP 0.0032 63.3 2 3110 2 196658 Polypharmacology Molecules Target Profile
191 DHFRP1 0.0032 63.3 2 3110 2 196658 Polypharmacology Molecules Target Profile
192 CCR8 0.0032 63.3 2 3110 2 196658 Polypharmacology Molecules Target Profile
193 CCR1 0.0032 63.3 2 3110 2 196658 Polypharmacology Molecules Target Profile
194 SLC22A1 0.0003009 47.5 3 3110 4 196658 Polypharmacology Molecules Target Profile
195 FYN 1.20e-09 42.3 8 3110 12 196658 Polypharmacology Molecules Target Profile
196 TBXAS1 2.93e-07 38.0 6 3110 10 196658 Polypharmacology Molecules Target Profile
197 TOP2A 4.76e-05 36.2 4 3110 7 196658 Polypharmacology Molecules Target Profile
198 TACR2 6.47e-07 31.7 6 3110 12 196658 Polypharmacology Molecules Target Profile
199 MAPK3 0.00071 31.6 3 3110 6 196658 Polypharmacology Molecules Target Profile
200 HMGCR 0.0075 31.6 2 3110 4 196658 Polypharmacology Molecules Target Profile
201 KIT 0.0075 31.6 2 3110 4 196658 Polypharmacology Molecules Target Profile
202 MAPK14 9.28e-07 29.2 6 3110 13 196658 Polypharmacology Molecules Target Profile
203 EGFR 5.71e-07 21.1 7 3110 21 196658 Polypharmacology Molecules Target Profile
204 SIGMAR1 0.00023 21.1 4 3110 12 196658 Polypharmacology Molecules Target Profile
205 XDH 0.013 21.1 2 3110 6 196658 Polypharmacology Molecules Target Profile
206 TYMS 0.013 21.1 2 3110 6 196658 Polypharmacology Molecules Target Profile
207 GCK 0.013 21.1 2 3110 6 196658 Polypharmacology Molecules Target Profile
208 CLK3 0.013 21.1 2 3110 6 196658 Polypharmacology Molecules Target Profile
209 NR1H3 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
210 FMO3 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
211 CYTH2 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
212 HDAC6 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
213 HDAC1 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
214 MC5R 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
215 HDAC2 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
216 MTHFR 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
217 UGT1A4 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
218 TERT 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
219 DCK 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
220 ESRRA 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
221 PLA2G4A 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
222 CBR3 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
223 TACR1 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
224 CDC25A 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
225 PTPRF 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
226 CYSLTR1 0.11 21.1 1 3110 3 196658 Polypharmacology Molecules Target Profile
227 ADRB3 0.0022 19.0 3 3110 10 196658 Polypharmacology Molecules Target Profile
228 SLC22A2 0.0022 19.0 3 3110 10 196658 Polypharmacology Molecules Target Profile
229 SLC47A2 0.017 18.1 2 3110 7 196658 Polypharmacology Molecules Target Profile
230 OPRD1 1.66e-05 15.8 6 3110 24 196658 Polypharmacology Molecules Target Profile
231 PTPN1 0.021 15.8 2 3110 8 196658 Polypharmacology Molecules Target Profile
232 TEK 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
233 HTR4 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
234 CYP11A1 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
235 CCR5 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
236 GSR 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
237 BRAF 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
238 PECR 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
239 PTGES 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
240 CACNA1G 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
241 TOP1 0.13 15.8 1 3110 4 196658 Polypharmacology Molecules Target Profile
242 ADRA2A 6.00e-07 15.4 8 3110 33 196658 Polypharmacology Molecules Target Profile
243 HBB 0.00014 14.4 5 3110 22 196658 Polypharmacology Molecules Target Profile
244 ADRA2C 5.00e-06 14.3 7 3110 31 196658 Polypharmacology Molecules Target Profile
245 PARK2 0.025 14.1 2 3110 9 196658 Polypharmacology Molecules Target Profile
246 SMPD1 0.0047 13.6 3 3110 14 196658 Polypharmacology Molecules Target Profile
247 CNR2 0.0047 13.6 3 3110 14 196658 Polypharmacology Molecules Target Profile
248 NFKBIA 0.0056 12.7 3 3110 15 196658 Polypharmacology Molecules Target Profile
249 PIM1 0.029 12.7 2 3110 10 196658 Polypharmacology Molecules Target Profile
250 GEM 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
251 CCNB1 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
252 PTPN6 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
253 RET 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
254 SLK 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
255 YES1 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
256 AKR1B10 0.15 12.7 1 3110 5 196658 Polypharmacology Molecules Target Profile
257 STAT6 0.0067 11.9 3 3110 16 196658 Polypharmacology Molecules Target Profile
258 SLC6A4 3.89e-06 11.5 8 3110 44 196658 Polypharmacology Molecules Target Profile
259 ADRA2B 7.85e-05 11.5 6 3110 33 196658 Polypharmacology Molecules Target Profile
260 CASP8 0.0015 11.5 4 3110 22 196658 Polypharmacology Molecules Target Profile
261 PLAU 0.033 11.5 2 3110 11 196658 Polypharmacology Molecules Target Profile
262 PIM2 0.033 11.5 2 3110 11 196658 Polypharmacology Molecules Target Profile
263 SLC6A2 9.47e-07 11.4 9 3110 50 196658 Polypharmacology Molecules Target Profile
264 HTR6 9.01e-05 11.2 6 3110 34 196658 Polypharmacology Molecules Target Profile
265 MGLL 0.17 10.5 1 3110 6 196658 Polypharmacology Molecules Target Profile
266 PDGFRB 0.17 10.5 1 3110 6 196658 Polypharmacology Molecules Target Profile
267 SMN1 0.17 10.5 1 3110 6 196658 Polypharmacology Molecules Target Profile
268 CNR1 0.00013 10.3 6 3110 37 196658 Polypharmacology Molecules Target Profile
269 CHRM2 0.0023 10.1 4 3110 25 196658 Polypharmacology Molecules Target Profile
270 PDE4A 0.049 9.0 2 3110 14 196658 Polypharmacology Molecules Target Profile
271 SLC47A1 0.049 9.0 2 3110 14 196658 Polypharmacology Molecules Target Profile
272 HRH2 0.049 9.0 2 3110 14 196658 Polypharmacology Molecules Target Profile
273 CASP9 0.049 9.0 2 3110 14 196658 Polypharmacology Molecules Target Profile
274 MAP3K5 0.18 9.0 1 3110 7 196658 Polypharmacology Molecules Target Profile
275 CES2 0.18 9.0 1 3110 7 196658 Polypharmacology Molecules Target Profile
276 CALM1 0.18 9.0 1 3110 7 196658 Polypharmacology Molecules Target Profile
277 METAP2 0.18 9.0 1 3110 7 196658 Polypharmacology Molecules Target Profile
278 CALM2 0.18 9.0 1 3110 7 196658 Polypharmacology Molecules Target Profile
279 PPARA 0.055 8.4 2 3110 15 196658 Polypharmacology Molecules Target Profile
280 HTR2C 0.00014 7.9 7 3110 56 196658 Polypharmacology Molecules Target Profile
281 FAAH 0.21 7.9 1 3110 8 196658 Polypharmacology Molecules Target Profile
282 KDR 0.21 7.9 1 3110 8 196658 Polypharmacology Molecules Target Profile
283 CHRM3 0.0017 7.7 5 3110 41 196658 Polypharmacology Molecules Target Profile
284 HTR2A 0.00017 7.6 7 3110 58 196658 Polypharmacology Molecules Target Profile
285 HTR1D 0.066 7.4 2 3110 17 196658 Polypharmacology Molecules Target Profile
286 PIN1 0.021 7.3 3 3110 26 196658 Polypharmacology Molecules Target Profile
287 ACHE 0.021 7.3 3 3110 26 196658 Polypharmacology Molecules Target Profile
288 PLEC 8.00e-05 7.2 8 3110 70 196658 Polypharmacology Molecules Target Profile
289 ACE 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
290 SRC 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
291 METAP1 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
292 CALM3 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
293 FLT3 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
294 PDE5A 0.22 7.0 1 3110 9 196658 Polypharmacology Molecules Target Profile
295 HSPA5 0.0089 6.7 4 3110 38 196658 Polypharmacology Molecules Target Profile
296 PTGS1 0.0089 6.7 4 3110 38 196658 Polypharmacology Molecules Target Profile
297 EZH2 0.086 6.3 2 3110 20 196658 Polypharmacology Molecules Target Profile
298 HK1 0.23 6.3 1 3110 10 196658 Polypharmacology Molecules Target Profile
299 CES1 0.23 6.3 1 3110 10 196658 Polypharmacology Molecules Target Profile
300 DRD4 0.094 6.0 2 3110 21 196658 Polypharmacology Molecules Target Profile
301 BCL2L2 0.013 5.9 4 3110 43 196658 Polypharmacology Molecules Target Profile
302 AOX1 0.26 5.8 1 3110 11 196658 Polypharmacology Molecules Target Profile
303 LMNA 0.26 5.8 1 3110 11 196658 Polypharmacology Molecules Target Profile
304 AURKB 0.26 5.8 1 3110 11 196658 Polypharmacology Molecules Target Profile
305 RELA 0.0058 5.7 5 3110 56 196658 Polypharmacology Molecules Target Profile
306 KDM4A 0.044 5.3 3 3110 36 196658 Polypharmacology Molecules Target Profile
307 RGS8 0.048 5.1 3 3110 37 196658 Polypharmacology Molecules Target Profile
308 ADRA1D 0.11 5.1 2 3110 25 196658 Polypharmacology Molecules Target Profile
309 RGS16 0.049 5.0 3 3110 38 196658 Polypharmacology Molecules Target Profile
310 MMP9 0.29 4.9 1 3110 13 196658 Polypharmacology Molecules Target Profile
311 ARNT 0.29 4.9 1 3110 13 196658 Polypharmacology Molecules Target Profile
312 RGS19 0.057 4.7 3 3110 40 196658 Polypharmacology Molecules Target Profile
313 PDE4B 0.32 4.5 1 3110 14 196658 Polypharmacology Molecules Target Profile
314 ALOX5 0.33 4.2 1 3110 15 196658 Polypharmacology Molecules Target Profile
315 PTK2B 0.021 4.0 5 3110 79 196658 Polypharmacology Molecules Target Profile
316 HTR1B 0.34 4.0 1 3110 16 196658 Polypharmacology Molecules Target Profile
317 AKR1B1 0.34 4.0 1 3110 16 196658 Polypharmacology Molecules Target Profile
318 CYP11B1 0.34 4.0 1 3110 16 196658 Polypharmacology Molecules Target Profile
319 TSG101 0.0032 3.9 8 3110 129 196658 Polypharmacology Molecules Target Profile
320 ADORA2A 0.103 3.7 3 3110 52 196658 Polypharmacology Molecules Target Profile
321 ERG 0.033 3.6 5 3110 89 196658 Polypharmacology Molecules Target Profile
322 PTGS2 0.18 3.5 2 3110 36 196658 Polypharmacology Molecules Target Profile
323 CA6 0.19 3.4 2 3110 37 196658 Polypharmacology Molecules Target Profile
324 RGS7 0.39 3.3 1 3110 19 196658 Polypharmacology Molecules Target Profile
325 CYP2D6 0.0102 3.2 8 3110 158 196658 Polypharmacology Molecules Target Profile
326 CDC25B 0.081 3.2 4 3110 80 196658 Polypharmacology Molecules Target Profile
327 CYP2E1 0.21 3.2 2 3110 40 196658 Polypharmacology Molecules Target Profile
328 HTR7 0.41 3.2 1 3110 20 196658 Polypharmacology Molecules Target Profile
329 SUMO2 0.43 3.0 1 3110 21 196658 Polypharmacology Molecules Target Profile
330 BCL2 0.059 3.0 5 3110 106 196658 Polypharmacology Molecules Target Profile
331 CYP3A7 0.23 2.9 2 3110 43 196658 Polypharmacology Molecules Target Profile
332 CTSL1 1.19e-12 2.9 65 3110 1420 196658 Polypharmacology Molecules Target Profile
333 IL8 0.15 2.9 3 3110 65 196658 Polypharmacology Molecules Target Profile
334 KCNK3 2.26e-20 2.9 111 3110 2481 196658 Polypharmacology Molecules Target Profile
335 TLR3 0.0075 2.9 10 3110 219 196658 Polypharmacology Molecules Target Profile
336 ALPI 2.80e-08 2.9 41 3110 905 196658 Polypharmacology Molecules Target Profile
337 GSTM1 0.027 2.9 7 3110 154 196658 Polypharmacology Molecules Target Profile
338 CYP1A1 0.25 2.9 2 3110 44 196658 Polypharmacology Molecules Target Profile
339 GPER 0.44 2.9 1 3110 22 196658 Polypharmacology Molecules Target Profile
340 KCNH2 5.24e-14 2.8 77 3110 1745 196658 Polypharmacology Molecules Target Profile
341 RGS12 0.25 2.8 2 3110 45 196658 Polypharmacology Molecules Target Profile
342 PIP4K2A 2.30e-22 2.8 130 3110 3015 196658 Polypharmacology Molecules Target Profile
343 MCL1 1.09e-38 2.8 240 3110 5744 196658 Polypharmacology Molecules Target Profile
344 HRH1 0.26 2.8 2 3110 46 196658 Polypharmacology Molecules Target Profile
345 STAT3 5.49e-24 2.8 145 3110 3436 196658 Polypharmacology Molecules Target Profile
346 GPR32 0.45 2.7 1 3110 23 196658 Polypharmacology Molecules Target Profile
347 POLI 1.07e-20 2.7 126 3110 3013 196658 Polypharmacology Molecules Target Profile
348 MCOLN1 0.0027 2.7 14 3110 331 196658 Polypharmacology Molecules Target Profile
349 LYPLA2 4.69e-08 2.7 45 3110 1072 196658 Polypharmacology Molecules Target Profile
350 MPI 1.46e-14 2.7 89 3110 2145 196658 Polypharmacology Molecules Target Profile
351 LARGE 6.85e-05 2.6 25 3110 602 196658 Polypharmacology Molecules Target Profile
352 CYP3A5 0.28 2.6 2 3110 49 196658 Polypharmacology Molecules Target Profile
353 SLC12A5 4.53e-21 2.5 146 3110 3754 196658 Polypharmacology Molecules Target Profile
354 CLK4 0.48 2.5 1 3110 25 196658 Polypharmacology Molecules Target Profile
355 HSD11B1 0.48 2.5 1 3110 25 196658 Polypharmacology Molecules Target Profile
356 CYP1B1 0.48 2.5 1 3110 25 196658 Polypharmacology Molecules Target Profile
357 POLK 7.11e-09 2.5 56 3110 1416 196658 Polypharmacology Molecules Target Profile
358 KDM4C 0.103 2.5 5 3110 126 196658 Polypharmacology Molecules Target Profile
359 SENP8 7.67e-32 2.5 235 3110 6211 196658 Polypharmacology Molecules Target Profile
360 CHRM1 7.49e-24 2.5 171 3110 4464 196658 Polypharmacology Molecules Target Profile
361 POLB 1.24e-18 2.5 130 3110 3367 196658 Polypharmacology Molecules Target Profile
362 TDP2 2.62e-06 2.5 38 3110 969 196658 Polypharmacology Molecules Target Profile
363 MRGPRX1 3.47e-32 2.5 241 3110 6418 196658 Polypharmacology Molecules Target Profile
364 GNAS 0.00059 2.5 21 3110 538 196658 Polypharmacology Molecules Target Profile
365 SENP6 2.59e-27 2.5 204 3110 5431 196658 Polypharmacology Molecules Target Profile
366 MLL 0.19 2.5 3 3110 77 196658 Polypharmacology Molecules Target Profile
367 ADRB1 0.49 2.4 1 3110 26 196658 Polypharmacology Molecules Target Profile
368 ALPPL2 1.42e-07 2.4 50 3110 1313 196658 Polypharmacology Molecules Target Profile
369 DRD1 1.95e-45 2.4 387 3110 11046 196658 Polypharmacology Molecules Target Profile
370 WHSC1 7.94e-07 2.4 46 3110 1233 196658 Polypharmacology Molecules Target Profile
371 TARDBP 6.08e-21 2.4 165 3110 4538 196658 Polypharmacology Molecules Target Profile
372 BCHE 0.509 2.3 1 3110 27 196658 Polypharmacology Molecules Target Profile
373 SELE 0.00044 2.3 25 3110 685 196658 Polypharmacology Molecules Target Profile
374 ESR1 9.21e-11 2.3 84 3110 2338 196658 Polypharmacology Molecules Target Profile
375 RORA 4.37e-06 2.3 44 3110 1235 196658 Polypharmacology Molecules Target Profile
376 S100A4 0.18 2.3 4 3110 112 196658 Polypharmacology Molecules Target Profile
377 VCAM1 0.13 2.2 5 3110 141 196658 Polypharmacology Molecules Target Profile
378 AHR 1.28e-26 2.2 249 3110 7405 196658 Polypharmacology Molecules Target Profile
379 ALOX15 0.00109 2.2 24 3110 689 196658 Polypharmacology Molecules Target Profile
380 PTK2 0.0012 2.2 24 3110 696 196658 Polypharmacology Molecules Target Profile
381 RACGAP1 1.29e-06 2.2 53 3110 1547 196658 Polypharmacology Molecules Target Profile
382 CA3 0.53 2.2 1 3110 29 196658 Polypharmacology Molecules Target Profile
383 NR4A1 0.25 2.2 3 3110 88 196658 Polypharmacology Molecules Target Profile
384 BCL2L1 9.98e-08 2.1 71 3110 2171 196658 Polypharmacology Molecules Target Profile
385 ERAP1 0.038 2.0 12 3110 374 196658 Polypharmacology Molecules Target Profile
386 PLK1 9.04e-23 2.0 272 3110 8982 196658 Polypharmacology Molecules Target Profile
387 CDC42 0.064 2.0 10 3110 317 196658 Polypharmacology Molecules Target Profile
388 PKM 0.0016 2.0 29 3110 930 196658 Polypharmacology Molecules Target Profile
389 CASP6 0.00025 2.0 39 3110 1254 196658 Polypharmacology Molecules Target Profile
390 CYP2B7P1 0.58 2.0 1 3110 32 196658 Polypharmacology Molecules Target Profile
391 PRMT1 1.11e-09 2.0 109 3110 3567 196658 Polypharmacology Molecules Target Profile
392 MBNL1 0.32 1.9 3 3110 99 196658 Polypharmacology Molecules Target Profile
393 PDIA6 0.58 1.9 1 3110 33 196658 Polypharmacology Molecules Target Profile
394 CASP3 2.35e-10 1.9 127 3110 4277 196658 Polypharmacology Molecules Target Profile
395 NR1I2 2.44e-05 1.9 57 3110 1905 196658 Polypharmacology Molecules Target Profile
396 SENP7 2.90e-12 1.9 158 3110 5385 196658 Polypharmacology Molecules Target Profile
397 GAA 0.00017 1.9 47 3110 1591 196658 Polypharmacology Molecules Target Profile
398 SLC6A3 0.00107 1.9 37 3110 1263 196658 Polypharmacology Molecules Target Profile
399 CYP2A6 0.59 1.9 1 3110 34 196658 Polypharmacology Molecules Target Profile
400 CYP2B6 0.59 1.9 1 3110 34 196658 Polypharmacology Molecules Target Profile
401 SLC5A7 3.03e-09 1.8 131 3110 4659 196658 Polypharmacology Molecules Target Profile
402 CTSS 0.609 1.8 1 3110 35 196658 Polypharmacology Molecules Target Profile
403 TRPV1 0.037 1.8 17 3110 599 196658 Polypharmacology Molecules Target Profile
404 RAC1 0.062 1.8 14 3110 500 196658 Polypharmacology Molecules Target Profile
405 CLK1 0.36 1.8 3 3110 107 196658 Polypharmacology Molecules Target Profile
406 HPGD 9.08e-09 1.7 144 3110 5376 196658 Polypharmacology Molecules Target Profile
407 YWHAG 0.48 1.7 2 3110 74 196658 Polypharmacology Molecules Target Profile
408 PTBP1 2.06e-06 1.7 102 3110 3831 196658 Polypharmacology Molecules Target Profile
409 PTPN5 0.042 1.7 19 3110 709 196658 Polypharmacology Molecules Target Profile
410 GLS 0.057 1.7 17 3110 635 196658 Polypharmacology Molecules Target Profile
411 EHMT2 3.21e-28 1.7 621 3110 25223 196658 Polypharmacology Molecules Target Profile
412 CACNA1H 3.85e-06 1.7 99 3110 3742 196658 Polypharmacology Molecules Target Profile
413 PAFAH2 0.00013 1.7 69 3110 2608 196658 Polypharmacology Molecules Target Profile
414 ADORA1 0.63 1.7 1 3110 38 196658 Polypharmacology Molecules Target Profile
415 STAT1 1.62e-07 1.7 140 3110 5454 196658 Polypharmacology Molecules Target Profile
416 CTSG 0.509 1.6 2 3110 78 196658 Polypharmacology Molecules Target Profile
417 CTSB 0.52 1.6 2 3110 79 196658 Polypharmacology Molecules Target Profile
418 INS 0.0058 1.6 47 3110 1903 196658 Polypharmacology Molecules Target Profile
419 TRHR 0.0024 1.6 58 3110 2358 196658 Polypharmacology Molecules Target Profile
420 SMARCA2 0.00083 1.6 72 3110 2949 196658 Polypharmacology Molecules Target Profile
421 PTPN7 0.34 1.5 5 3110 205 196658 Polypharmacology Molecules Target Profile
422 CA4 0.67 1.5 1 3110 41 196658 Polypharmacology Molecules Target Profile
423 CA5A 0.67 1.5 1 3110 41 196658 Polypharmacology Molecules Target Profile
424 KPNA2 0.23 1.5 9 3110 377 196658 Polypharmacology Molecules Target Profile
425 DRD2 1.42e-07 1.5 210 3110 9018 196658 Polypharmacology Molecules Target Profile
426 CA2 0.54 1.5 2 3110 84 196658 Polypharmacology Molecules Target Profile
427 CCT2 0.56 1.5 2 3110 85 196658 Polypharmacology Molecules Target Profile
428 PAFAH1B2 0.00204 1.5 80 3110 3471 196658 Polypharmacology Molecules Target Profile
429 GSK3A 0.12 1.4 21 3110 924 196658 Polypharmacology Molecules Target Profile
430 MAOB 0.708 1.4 1 3110 44 196658 Polypharmacology Molecules Target Profile
431 BCL2L10 0.509 1.4 3 3110 134 196658 Polypharmacology Molecules Target Profile
432 ADRBK1 0.051 1.4 38 3110 1706 196658 Polypharmacology Molecules Target Profile
433 CA14 0.71 1.4 1 3110 45 196658 Polypharmacology Molecules Target Profile
434 ESR2 0.15 1.4 21 3110 961 196658 Polypharmacology Molecules Target Profile
435 GFER 8.52e-05 1.4 211 3110 10044 196658 Polypharmacology Molecules Target Profile
436 GNAO1 0.12 1.4 30 3110 1407 196658 Polypharmacology Molecules Target Profile
437 CA7 0.73 1.3 1 3110 48 196658 Polypharmacology Molecules Target Profile
438 ABCC1 0.32 1.3 15 3110 747 196658 Polypharmacology Molecules Target Profile
439 GSK3B 0.37 1.3 11 3110 548 196658 Polypharmacology Molecules Target Profile
440 RAD51 0.59 1.3 3 3110 150 196658 Polypharmacology Molecules Target Profile
441 PABPC1 0.064 1.3 72 3110 3624 196658 Polypharmacology Molecules Target Profile
442 PLCB3 0.41 1.3 10 3110 505 196658 Polypharmacology Molecules Target Profile
443 ID4 0.77 1.2 1 3110 52 196658 Polypharmacology Molecules Target Profile
444 PTH1R 0.609 1.2 4 3110 211 196658 Polypharmacology Molecules Target Profile
445 ALDH1A1 0.015 1.2 251 3110 13590 196658 Polypharmacology Molecules Target Profile
446 WEE1 0.25 1.2 43 3110 2309 196658 Polypharmacology Molecules Target Profile
447 CYP2C9 0.0096 1.2 330 3110 18095 196658 Polypharmacology Molecules Target Profile
448 ARRB1 0.45 1.2 17 3110 933 196658 Polypharmacology Molecules Target Profile
449 MMP13 0.79 1.1 1 3110 55 196658 Polypharmacology Molecules Target Profile
450 EIF4H 0.36 1.1 43 3110 2422 196658 Polypharmacology Molecules Target Profile
451 HCRTR2 0.83 1.1 1 3110 59 196658 Polypharmacology Molecules Target Profile
452 PTPN22 0.74 1.1 3 3110 180 196658 Polypharmacology Molecules Target Profile
453 EPHB4 0.78 1.0 2 3110 121 196658 Polypharmacology Molecules Target Profile
454 MAP3K3 0.62 1.0 61 3110 3763 196658 Polypharmacology Molecules Target Profile
455 CTDSP1 0.64 1.0 39 3110 2414 196658 Polypharmacology Molecules Target Profile
456 MBD2 0.71 1.0 12 3110 748 196658 Polypharmacology Molecules Target Profile
457 PLCG1 0.77 1.0 37 3110 2379 196658 Polypharmacology Molecules Target Profile
458 ROCK2 0.809 1.0 3 3110 193 196658 Polypharmacology Molecules Target Profile
459 CA9 0.89 0.9 1 3110 68 196658 Polypharmacology Molecules Target Profile
460 FPR2 0.89 0.9 1 3110 68 196658 Polypharmacology Molecules Target Profile
461 CA12 0.89 0.9 1 3110 68 196658 Polypharmacology Molecules Target Profile
462 MARVELD2 0.89 0.9 13 3110 899 196658 Polypharmacology Molecules Target Profile
463 SIRT5 0.95 0.9 23 3110 1605 196658 Polypharmacology Molecules Target Profile
464 DUSP3 0.97 0.9 23 3110 1627 196658 Polypharmacology Molecules Target Profile
465 PHOSPHO1 0.99 0.9 40 3110 2844 196658 Polypharmacology Molecules Target Profile
466 CYP2C8 0.92 0.9 1 3110 73 196658 Polypharmacology Molecules Target Profile
467 CA1 0.93 0.9 1 3110 74 196658 Polypharmacology Molecules Target Profile
468 UHRF1 0.99 0.8 26 3110 1954 196658 Polypharmacology Molecules Target Profile
469 NPC1 0.99 0.8 91 3110 6829 196658 Polypharmacology Molecules Target Profile
470 HRAS 0.94 0.8 3 3110 229 196658 Polypharmacology Molecules Target Profile
471 FPR1 0.93 0.8 2 3110 153 196658 Polypharmacology Molecules Target Profile
472 SMN2 0.99 0.8 61 3110 4934 196658 Polypharmacology Molecules Target Profile
473 CREBBP 0.96 0.8 1 3110 82 196658 Polypharmacology Molecules Target Profile
474 RAB9A 0.99 0.7 98 3110 8217 196658 Polypharmacology Molecules Target Profile
475 KLK5 0.99 0.7 13 3110 1119 196658 Polypharmacology Molecules Target Profile
476 PRKACA 0.99 0.7 1 3110 92 196658 Polypharmacology Molecules Target Profile
477 NR0B1 0.99 0.7 62 3110 5714 196658 Polypharmacology Molecules Target Profile
478 BRCA1 0.99 0.7 43 3110 4004 196658 Polypharmacology Molecules Target Profile
479 PRKD1 0.99 0.7 1 3110 94 196658 Polypharmacology Molecules Target Profile
480 DUSP1 0.99 0.7 1 3110 96 196658 Polypharmacology Molecules Target Profile
481 DRD5 0.99 0.6 1 3110 99 196658 Polypharmacology Molecules Target Profile
482 CYP2C19 0.99 0.6 185 3110 18449 196658 Polypharmacology Molecules Target Profile
483 MAPK10 0.99 0.6 3 3110 317 196658 Polypharmacology Molecules Target Profile
484 KLK7 0.99 0.6 25 3110 2649 196658 Polypharmacology Molecules Target Profile
485 EIF2AK3 0.99 0.6 3 3110 335 196658 Polypharmacology Molecules Target Profile
486 EPHX2 0.99 0.6 3 3110 336 196658 Polypharmacology Molecules Target Profile
487 F11 0.99 0.5 3 3110 395 196658 Polypharmacology Molecules Target Profile
488 F12 0.99 0.5 5 3110 673 196658 Polypharmacology Molecules Target Profile
489 APOBEC3A 0.99 0.5 9 3110 1254 196658 Polypharmacology Molecules Target Profile
490 FGF22 0.99 0.4 25 3110 3708 196658 Polypharmacology Molecules Target Profile
491 RXFP1 0.99 0.4 4 3110 676 196658 Polypharmacology Molecules Target Profile
492 AKT1 0.99 0.4 6 3110 1039 196658 Polypharmacology Molecules Target Profile
493 F2 0.99 0.3 2 3110 459 196658 Polypharmacology Molecules Target Profile
494 ABL1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
495 F3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
496 MPO 0.99 0.0 0 3110 10 196658 Polypharmacology Molecules Target Profile
497 GABRA5 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
498 PTGDR2 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
499 GRIA2 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
500 AMY1C 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
501 PMM2 0.99 0.0 0 3110 16 196658 Polypharmacology Molecules Target Profile
502 CACNA1S 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
503 CDK2 0.99 0.0 0 3110 10 196658 Polypharmacology Molecules Target Profile
504 FKBP1A 0.99 0.0 0 3110 22 196658 Polypharmacology Molecules Target Profile
505 MMP12 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
506 CYP11B2 0.99 0.0 0 3110 11 196658 Polypharmacology Molecules Target Profile
507 DHODH 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
508 GAK 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
509 G6PD 0.99 0.0 0 3110 17 196658 Polypharmacology Molecules Target Profile
510 BACE1 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
511 UGT1A1 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
512 DYRK1A 0.99 0.0 0 3110 22 196658 Polypharmacology Molecules Target Profile
513 ABCC8 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
514 SCN5A 0.99 0.0 0 3110 15 196658 Polypharmacology Molecules Target Profile
515 GABRA1 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
516 F2RL1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
517 PTGER4 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
518 DYRK1B 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
519 PTPN12 0.99 0.0 0 3110 27 196658 Polypharmacology Molecules Target Profile
520 SIRT2 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
521 PTPN11 0.99 0.0 0 3110 134 196658 Polypharmacology Molecules Target Profile
522 STK3 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
523 CA13 0.99 0.0 0 3110 20 196658 Polypharmacology Molecules Target Profile
524 GRM5 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
525 APEX1 0.99 0.0 0 3110 17 196658 Polypharmacology Molecules Target Profile
526 HTR1F 0.99 0.0 0 3110 11 196658 Polypharmacology Molecules Target Profile
527 RXFP2 0.99 0.0 0 3110 162 196658 Polypharmacology Molecules Target Profile
528 PTGIR 0.99 0.0 0 3110 10 196658 Polypharmacology Molecules Target Profile
529 NOS2 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
530 GLA 0.99 0.0 0 3110 32 196658 Polypharmacology Molecules Target Profile
531 PDE3A 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
532 SCN1A 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
533 XIAP 0.99 0.0 0 3110 19 196658 Polypharmacology Molecules Target Profile
534 SIRT1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
535 TSPO 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
536 UGT2B7 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
537 SLCO1B1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
538 TYK2 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
539 AKR1C1 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
540 GPBAR1 0.99 0.0 0 3110 13 196658 Polypharmacology Molecules Target Profile
541 GSTA2 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
542 MIF 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
543 MYC 0.99 0.0 0 3110 36 196658 Polypharmacology Molecules Target Profile
544 PTPRB 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
545 SLC12A1 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
546 CSNK2A1 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
547 UGT1A9 0.99 0.0 0 3110 12 196658 Polypharmacology Molecules Target Profile
548 C1S 0.99 0.0 0 3110 87 196658 Polypharmacology Molecules Target Profile
549 SCN4A 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
550 GABRA3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
551 LTA4H 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
552 CACNB2 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
553 TNKS 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
554 HSD17B1 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
555 PGR 0.99 0.0 0 3110 17 196658 Polypharmacology Molecules Target Profile
556 FLT4 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
557 PTGDR 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
558 MAP2K1 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
559 SLC12A3 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
560 NTSR2 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
561 ADORA2B 0.99 0.0 0 3110 20 196658 Polypharmacology Molecules Target Profile
562 MEN1 0.99 0.0 0 3110 12 196658 Polypharmacology Molecules Target Profile
563 AKR1C3 0.99 0.0 0 3110 15 196658 Polypharmacology Molecules Target Profile
564 ARSA 0.99 0.0 0 3110 11 196658 Polypharmacology Molecules Target Profile
565 PTGER3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
566 HPSE 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
567 STK16 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
568 SHBG 0.99 0.0 0 3110 27 196658 Polypharmacology Molecules Target Profile
569 HTR3A 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
570 ANPEP 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
571 GLO1 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
572 HSD17B3 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
573 MMP1 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
574 NQO2 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
575 GABRA2 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
576 CSF1R 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
577 NR3C2 0.99 0.0 0 3110 12 196658 Polypharmacology Molecules Target Profile
578 AVPR1B 0.99 0.0 0 3110 184 196658 Polypharmacology Molecules Target Profile
579 PARP1 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
580 CGA 0.99 0.0 0 3110 201 196658 Polypharmacology Molecules Target Profile
581 GRM4 0.99 0.0 0 3110 22 196658 Polypharmacology Molecules Target Profile
582 CBR1 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
583 AKR1C2 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
584 NOX1 0.99 0.0 0 3110 38 196658 Polypharmacology Molecules Target Profile
585 MMP3 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
586 ESRRG 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
587 CYP51A1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
588 CACNA1D 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
589 HRH3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
590 NOS3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
591 HPGDS 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
592 PLA2G2E 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
593 MAPK15 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
594 ADRA1B 0.99 0.0 0 3110 11 196658 Polypharmacology Molecules Target Profile
595 KEAP1 0.99 0.0 0 3110 21 196658 Polypharmacology Molecules Target Profile
596 CHRNA7 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
597 CACNA1C 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
598 TNKS2 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
599 CA5B 0.99 0.0 0 3110 39 196658 Polypharmacology Molecules Target Profile
600 CYP17A1 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
601 ALB 0.99 0.0 0 3110 10 196658 Polypharmacology Molecules Target Profile
602 QPCT 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
603 MAOA 0.99 0.0 0 3110 35 196658 Polypharmacology Molecules Target Profile
604 PTP4A3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
605 HCAR2 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
606 CYP2C18 0.99 0.0 0 3110 11 196658 Polypharmacology Molecules Target Profile
607 PDE4D 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
608 PLA2G2A 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
609 HRH4 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
610 SCN9A 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
611 NOTCH1 0.99 0.0 0 3110 9 196658 Polypharmacology Molecules Target Profile
612 SCN10A 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
613 RNASEH1 0.99 0.0 0 3110 6 196658 Polypharmacology Molecules Target Profile
614 KCNMA1 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
615 IDO1 0.99 0.0 0 3110 8 196658 Polypharmacology Molecules Target Profile
616 SLCO1B3 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
617 CACNA2D1 0.99 0.0 0 3110 7 196658 Polypharmacology Molecules Target Profile
618 ELANE 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
619 GRM1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
620 JAK1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
621 ADRA1A 0.99 0.0 0 3110 17 196658 Polypharmacology Molecules Target Profile
622 CACNA2D2 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
623 UGT1A3 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
624 CSK 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
625 TRPA1 0.99 0.0 0 3110 4 196658 Polypharmacology Molecules Target Profile
626 ABCC2 0.99 0.0 0 3110 5 196658 Polypharmacology Molecules Target Profile
627 ERAP2 0.99 0.0 0 3110 41 196658 Polypharmacology Molecules Target Profile