PPI spider implements Global Network statistical framework to analyze gene/protein list using as reference knowledge a global protein-protein interaction network from IntAct database. For the human genome, the reference network covers about 7960 genes involved in approximately 40,000 unique pairwise interactions.
Reference: if you will find the results produced by PPI spider usefull, please cite:
1. Antonov A.V., Dietmann S., Rodchenkov I., Mewes H.W. PPI spider: A tool for the interpretation of proteomics data in the context of protein protein interaction networks. PROTEOMICS. Volume 9, Issue 10, 10 May 2009.